MiPschool Obergurgl 2017

MiPschool Obergurgl 2017

Obergurgl AT, 2017 Jul 23-30. 10th MiPschool 2017 MITOEAGLE and MITOEAGLE Workshop WG1-4.

Mitochondrial Physiology Society (2017-07-23) MitoGlobal

Abstract: 2017 Jul 23-30, Obergurgl, AT.

Date, venue, organization

• 2017 July 23-30

• 2017 July 23-27 Training School jointly organized by the Mitochondrial Physiology Society and COST Action MITOEAGLE
• 2017 July 27-30 MITOEAGLE Workshop: WG1-4

• University Centre Obergurgl, Tyrol, Austria

Programme

Click to expand or collaps

» Programme structure

• 2017-07-23, Day 1: Arrival
• 2017-07-24 to 26, Day 2-4: Training school MiPsociety and MITOEAGLE
  • Day 2-3: Intoductory lectures on the mitochondrial electron transfer system (ETS), coupling of electron transfer to proton translocation and phosphorylation (OXPHOS), mitochondrial pathways, respiratory protocols for diagnosis of mitochondrial function, mitochondrial respiratory control in health and disease.
  • Day 4: Scientific lectures and student presentations
• 2017-07-27, Day 5: Departure Training school, arrival MITOEAGLE workshop, relaxing day for overall-participants
• 2017-07-28 to 29, Day 6-7: MITOEAGLE Workshop: WG1-4
  • WG1: Harmonization of nomenclature on mitochondrial respiratory states and control parameters: Status of the consensus paper on a consistent terminology on mitochondrial physiology and bioenergetics; recommendations for the use of a common terminology in mitochondrial physiological research as a milestone towards unification of concepts and nomenclature.
  • WG1: Respirometric reference protocols: (i) Standard format for presenting substrate-uncoupler-inhibitor titration (SUIT) protocols for a ‘library of protocols’ applied in mitochondrial respiratory physiology; (ii) criteria for selecting and recommending reference protocols; (iii) documentation of the state-of-the-art standards in designing, conducting, reporting, interpreting, and validating SUIT protocols (compare: Maelstrom Research program).
  • WG2-4: Data repositories
• 2017-07-30, Day 8: Departure MITOEAGLE

Preliminary programme MiPschool (Jul 23-27)

This MiPschool will focus on basic concepts on mitochondrial respiratory states and applications of substrate-uncoupler-inhibitor titration (SUIT) protocols.

• • • • 2017-07-24

Session A (morning) Introduction: coupling control in oxidative phosphorylation

A1. The electron transfer system – Q redox regulation and mitochondrial pathways to oxygen (Anthony L Moore, University of Sussex, UK).

• A2. Coupling of the phosphorylation system to electron transfer and respiratory coupling control (Vilma Borutaite).
• A3. From Einstein's diffusion equation to Mitchell’s chemiosmotic equation: rates and states in the bioenergetics of oxidative phosphorylation (Erich Gnaiger).

A4. Biochemical coupling efficiency and ATP/O₂ ratios (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).

Session B (afternoon) Posters and selected abstracts

• B1. Poster session.
• B2: Selected abstracts: measurement of coupling control in intact cells and mitochondrial preparations - open discussion.
• B3. Towards a data base on coupling control in intact cells.

• • • • 2017-07-25

Session C (morning) Introduction: from experimental design to data analysis

• C1. Respiratory pathway control in mitochondrial preparations.
• C2. Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles (Carolina Doerrier).
• C3. Normalization of respiratory flux and flow.
• C4. Respiratory control ratios and control factors.

Session D (afternoon) Posters and selected abstracts

• D1. Selected abstracts: applications of SUIT protocols – open discussion.
• D2. SUIT protocols: design and limitations.
• D3. Towards a data base on mitochondrial respiratory control: diagnostic approaches and comparative mitochondrial physiology.

• • • • 2017-07-26

Session E (morning) Mitochondrial physiology: biomedical applications (possible titles, depending on keynote lecturers/selected abstracts)

• E1. The challenges of functional mitochondrial diagnosis (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).
• E2. Mitochondrial fitness in skeletal muscle (Pablo Garcia-Roves, University of Barcelona, ES).
• E3. Scope and limitations of functional mitochondrial diagnosis in blood cells.
• E4. Mitochondrial respiratory function and neuromuscular disease.
• E5. Mitochondrial function and dysfunction in cancer (Richard K Porter, Trinity College Dublin, IE).
• E6. Ischemia-reperfusion injury.

* E7. The metabolic syndrome - dysmitochondrial syndrome and mitochondrial disruptors (Hong Kyu Lee, Eulji University College of Medicine, Seoul, KR).

• E8. Mitochondrial function in aging and regeneration (Pidder Jansen-Duerr, University of Innsbruck, AT).

Session F (afternoon) Comparative mitochondrial physiology (possible titles, depending on keynote lecturers/selected abstracts)

• F1. Mitochondrial physiology in cell models versus primary tissue.
• F2. Mitochondrial physiology studies in mouse models.
• F3. Mitochondrial vertrebrate physiology – extreme performers.
• F5. Mitochondrial physiology of and beyond established animal models.
• F6. Mitochondrial physiology in plants (Anthony L Moore, University of Sussex, UK).
• F7. Mitochondrial physiology and evolution.

Session G (evening) MITOEAGLE Early Career Investigators forum

• MITOEAGLE Early Career Investigators

Preliminary programme MITOEAGLE Workshop WG1-4 (Jul 27-30)

currently in progress

Abstracts

Abstract submission: until May 31, 2017.

The abstract title has to be included on the registration form.

• Categories: Early career investigators (ECI) and students are invited to submit abstracts in four alternative categories and apply with their submission for a MITOEAGLE Scholarship:

1. SUIT protocols: basic concepts. - » MitoPedia: SUIT
2. SUIT protocols: various applications with intact cells and mt-preparations.
3. Discuss definitions and controversies for a selected term on respiratory states and respiratory control ratios. - » MitoPedia: Respiratory states, MitoPedia: Respiratory control ratios
4. Present your abstract as a definition of a term in the context of mitochondrial physiology that is missing in MitoPedia. - » MitoPedia

• Format

Abstract format

Example: Doerrier 2017 Abstract MITOEAGLE Barcelona

• Abstract submission and review for MITOEAGLE Scholarships

1. Eligibility: Early career investigators and students from all COST countries and International Partner Countries can apply - MITOEAGLE network.

2. You need to select a 'Mentor' who will act as the contact to review your abstract and recommend you as a recipient of the MITOEAGLE scholarship.

3. Check the MITOEAGLE mentors website for the Training School, and select a 'Mentor'.

4. Click on the highlighted name of the mentor for further details.

• Each mentor has two slots available. You can see in the column Booked whether the mentor is already booked or not.
• If you see that your preference no. 1 mentor already has one 'student', you might consider going for another mentor.

5. Prepare your abstract in the format given above.

• Add the name of your selected mentor as a final section of your abstract.
• Cover letter: Provide a brief explanation to your selected mentor in a form of a cover letter.

6. Send an Email to your mentor (and in Cc to [email protected]). Mention MITOEAGLE mentor in the subject line of your Email. Attach your abstract as a MS Word file and the cover letter.

7. Experimental abstracts will be reviewed and accepted entirely independent of the experimental platform used in the study, and a wide variety of experimental approaches is highly welcome.

» Notificiation of MITOEAGLE scholarships: 2017-06-10.

Support

MITOEAGLE scholarships for Early Career Investigators and students

• Submitted abstracts provide the basis for allocation of MITOEAGLE scholarships.
• Proposed deadline: 2017-May-31.
• 42 basic scholarships will cover the local costs (accommodation, meals and registration).
• Students from Inclusiveness Target Countries are eligible for extended scholarships covering travel costs in addition to the basic scholarship.

• Abstracts submitted with data suitable for the data bases Working Groups 2, 3 and 4 or Working Group 1 are selected as a basis of additional support for joining the MITOEAGLE Workshop WG1-4 (Jul 27-30).
• MITOEAGLE Working Group participants are supported (as far as possible) to join the Training School to be better prepared for the collaboration in the WG meeting, particularly the group working on the terminology review on respiratory states.

» Notificiation of MITOEAGLE scholarships: 2017-06-10.

Scholarships by the Medical University of Innsbruck

• 10 students of the Medical University of Innsbruck will be supported by a scholarship. The scholarship will cover 80 % of the registration/accommodation costs.

» For further questions, please contact the MITOEAGLE representatives of the training schools:

Uwe Schlattner

Ayse Basak Engin

» Further details on mentorship: consult MITOEAGLE Early Career Investigators

» List of MITOEAGLE mentors

Registration

MiPschool registration Early Career Investigators and students

» ECI and students registration

» Regular registration

MITOEAGLE Workshop WG1-4

» Registration form

Please send the completed form to [email protected]

Travel info

How to get there? Find out more: Travel info

Funding

• COST Action CA15203 Mitochondrial fitness mapping - MITOEAGLE

The project MitoFit is funded by the Land Tirol within the program K-Regio of Standortagentur Tirol.

10 years ago

» MiPschool Schroecken AT 2007

Listed under MitoGlobal Events.

Labels:

2017, ORO, MitoFit, MITOEAGLE, Next