Difference between revisions of "Bioblast alert 2012"
From Bioblast
Beno Marija (talk | contribs) |
|||
| (22 intermediate revisions by 6 users not shown) | |||
| Line 1: | Line 1: | ||
[[Image: | {{Bioblast header page name}} | ||
[[File:Bioblast alert.jpg|240px|right | [[Image:BB-Bioblast.jpg|left|30px|link=Bioblast:About|Bioblast wiki]] | ||
[[File:Bioblast alert.jpg|240px|right|link=Bioblast_alert|Bioblast alert]] | |||
'''[[Bioblast alert|back to "Bioblast alert" main page]]''' | |||
__TOC__ | __TOC__ | ||
=== Bioblast alert 2012(01): 2012-02-27 === | === Bioblast alert 2012(01): 2012-02-27 === | ||
Two exciting publications on '''mitochondrial [[p50|''p''<sub>50</sub>]]''', apparent [[excess capacity]] of cytochrome c oxidase, '''[[basal metabolic rate]]''', [[P/O ratio]]s and ergometric [[efficiency]]: | Two exciting publications on '''mitochondrial [[p50|''p''<sub>50</sub>]]''', apparent [[excess capacity]] of cytochrome c oxidase, '''[[basal metabolic rate]]''', [[P/O ratio]]s and ergometric [[efficiency]]: | ||
# [[Larsen_2011_FASEB_J|Larsen FJ, Schiffer TA, Sahlin K, Ekblom B, Weitzberg E, Lundberg JO (2011) Mitochondrial oxygen affinity predicts basal metabolic rate in humans. FASEB J 25: 2843- | # [[Larsen_2011_FASEB_J|Larsen FJ, Schiffer TA, Sahlin K, Ekblom B, Weitzberg E, Lundberg JO (2011) Mitochondrial oxygen affinity predicts basal metabolic rate in humans. FASEB J 25: 2843-52.]] | ||
# [[Larsen_2011_Cell_Metab|Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, Weitzberg E (2011) Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metab 13: 149- | # [[Larsen_2011_Cell_Metab|Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, Weitzberg E (2011) Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metab 13: 149-59.]] | ||
=== Bioblast alert 2012(02): 2012-03-06 === | === Bioblast alert 2012(02): 2012-03-06 === | ||
* '''50 Years ago''': '''Nick Holonyak''', considered as the "father of the light-emitting diode", developed the first practical '''visible-spectrum LED in 1962'''. ''Which colour? What is a'' '''LED'''''?'' >>> see '''[[Light emitting diode| | * '''50 Years ago''': '''Nick Holonyak''', considered as the "father of the light-emitting diode", developed the first practical '''visible-spectrum LED in 1962'''. ''Which colour? What is a'' '''LED'''''?'' >>> see '''[[Light emitting diode|MitoPedia: Fluorometry]]''' | ||
'''Mitochondrial dys/function in obesity vs. anorexia''': | '''Mitochondrial dys/function in obesity vs. anorexia''': | ||
# [[Lindfors 2011 Proc Natl Acad Sci U S A|Lindfors C, Nilsson IA, Garcia-Roves PM, Zuberi AR, Karimi M, Donahue LR, Roopenian DC, Mulder J, Uhlén M, Ekström TJ, Davisson MT, Hökfelt TG, Schalling M, Johansen JE (2011) Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse. Proc Natl Acad Sci U S A 108: 18108- | # [[Lindfors 2011 Proc Natl Acad Sci U S A|Lindfors C, Nilsson IA, Garcia-Roves PM, Zuberi AR, Karimi M, Donahue LR, Roopenian DC, Mulder J, Uhlén M, Ekström TJ, Davisson MT, Hökfelt TG, Schalling M, Johansen JE (2011) Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse. Proc Natl Acad Sci U S A 108: 18108-13.]] | ||
# [[Holmstroem 2012 Am J Physiol Endocrinol Metab|Holmstroem MH, Iglesias-Gutierrez E, Zierath JR, Garcia-Roves PM (2012) Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes. Am J Physiol Endocrinol Metab 302: E731- | # [[Holmstroem 2012 Am J Physiol Endocrinol Metab|Holmstroem MH, Iglesias-Gutierrez E, Zierath JR, Garcia-Roves PM (2012) Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes. Am J Physiol Endocrinol Metab 302: E731-9.]] | ||
=== Bioblast alert 2012(03): 2012-03-23 / 2012-04-03 === | === Bioblast alert 2012(03): 2012-03-23 / 2012-04-03 === | ||
''' | '''Bioblast topic''': '''[[Permeabilized_muscle_fibres#Oxygen_dependence_of_ROS_production_-_are_permeabilized_fibres_a_valid_model.3F|Oxygen dependence of ROS production - are permeabilized fibres a valid model?]]''' | ||
--> [[Talk:Permeabilized muscle fibres|'''''Discussion''''']] | --> [[Talk:Permeabilized muscle fibres|'''''Discussion''''']] | ||
'''''Drosophila'' vs. sandworm: High-resolution respirometry in permeabilized muscle fibres''' | '''''Drosophila'' vs. sandworm: High-resolution respirometry in permeabilized muscle fibres''' | ||
# [[Pichaud 2012 Comp Biochem Physiol A Mol Integr Physiol|Pichaud N, Rioux P, Blier PU (2012) In situ quantification of mitochondrial respiration in permeabilized fibers of a marine invertebrate with low aerobic capacity. Comp Biochem Physiol A Mol Integr Physiol 161: 429- | # [[Pichaud 2012 Comp Biochem Physiol A Mol Integr Physiol|Pichaud N, Rioux P, Blier PU (2012) In situ quantification of mitochondrial respiration in permeabilized fibers of a marine invertebrate with low aerobic capacity. Comp Biochem Physiol A Mol Integr Physiol 161: 429-35.]] | ||
# [[Pichaud 2011 Am J Physiol Regul Integr Comp Physiol|Pichaud N, Ballard JW, Tanguay RM, Blier PU (2011) Thermal sensitivity of mitochondrial functions in permeabilized muscle fibers from two populations of Drosophila simulans with divergent mitotypes. Am J Physiol Regul Integr Comp Physiol 301: R48- | # [[Pichaud 2011 Am J Physiol Regul Integr Comp Physiol|Pichaud N, Ballard JW, Tanguay RM, Blier PU (2011) Thermal sensitivity of mitochondrial functions in permeabilized muscle fibers from two populations of Drosophila simulans with divergent mitotypes. Am J Physiol Regul Integr Comp Physiol 301: R48-9.]] | ||
''New from the Ballard lab'': | ''New from the Ballard lab'': | ||
* [[Horan 2012 J Gerontol A Biol Sci Med Sci|Horan MP, Pichaud N, Ballard JW (2012) Review: Quantifying mitochondrial dysfunction in complex diseases of aging. J Gerontol A Biol Sci Med Sci | * [[Horan 2012 J Gerontol A Biol Sci Med Sci|Horan MP, Pichaud N, Ballard JW (2012) Review: Quantifying mitochondrial dysfunction in complex diseases of aging. J Gerontol A Biol Sci Med Sci 67:1022-35.]] | ||
=== Bioblast alert 2012(04): 2012-04-29 === | === Bioblast alert 2012(04): 2012-04-29 === | ||
* ''' | * '''Bioblast topic''': '''''Mitochondria''''' - can we decide on a common abbreviation? - or simply call them '''''[[Bioblasts]]'''''. --> '''[[Mitochondria]]''' and [[Talk:Mitochondria]] | ||
* '''Bioblast news''': '''Light in the powerhouse of the cells''' - [ | * '''Bioblast news''': '''Light in the powerhouse of the cells''' - [[Houska Award 2012| a mt-project is the winner of the Houska Award 2012]]. | ||
* '''Comparative mt-physiology - life style and training:''' | * '''Comparative mt-physiology - life style and training:''' | ||
::[[Votion 2012 PLoS One|Votion DM, Gnaiger E, Lemieux H, Mouithys-Mickalad A, Serteyn D (2012) Physical fitness and mitochondrial respiratory capacity in horse skeletal muscle. PLoS One 7(4): e34890.]] | ::[[Votion 2012 PLoS One|Votion DM, Gnaiger E, Lemieux H, Mouithys-Mickalad A, Serteyn D (2012) Physical fitness and mitochondrial respiratory capacity in horse skeletal muscle. PLoS One 7(4): e34890.]] | ||
=== Bioblast alert 2012(05): 2012-06-05 === | === Bioblast alert 2012(05): 2012-06-05 === | ||
* ''' | * '''Bioblast topic''': '''''Mitochondria and Genetics''''' - '''''[[Peroxisome proliferator-activated receptor gamma coactivator 1-alpha|the Coactivator PGC-1α]]''''' | ||
* '''Bioblast announcement''': [http://www.umdf.org/site/c.piKYL1PHLtF/b.4864979/k.C003/Home.htm UMDF: Mitochondrial Medicine 2012] - 2012-June-13 to 16 - Capitol Hill, Bethesda, Washington DC, USA | * '''Bioblast announcement''': [http://www.umdf.org/site/c.piKYL1PHLtF/b.4864979/k.C003/Home.htm UMDF: Mitochondrial Medicine 2012] - 2012-June-13 to 16 - Capitol Hill, Bethesda, Washington DC, USA | ||
* '''Comparison of common bioenergetic analysis methods''': [[Zhang_2012_Nat Protoc|Zhang J, Nuebel E, Wisidagama DR, Setoguchi K, Hong JS, Van Horn CM, Imam SS, Vergnes L, Malone CS, Koehler CM, Teitell MA (2012) Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells Nat Protoc 7: 1068- | * '''Comparison of common bioenergetic analysis methods''': [[Zhang_2012_Nat Protoc|Zhang J, Nuebel E, Wisidagama DR, Setoguchi K, Hong JS, Van Horn CM, Imam SS, Vergnes L, Malone CS, Koehler CM, Teitell MA (2012) Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells Nat Protoc 7: 1068-85.]] >> ''Continue the [[O2k_versus_multiwell_respirometer|discussion]]'' | ||
=== | === Bioblast alert 2012(06): 2012-07-20 === | ||
* ''' | * '''Bioblast news''': [[Myxothiazol]] is available again, ''but what about'' [[glycerophosphate|α-glycerophosphate]] ? | ||
:: >> More information on | :: >> More information on '''[[MitoPedia: Substrates and metabolites]]''' | ||
* ''' | * '''Bioblast terminology''': [[State 3]] - is [ADP] saturating? ''Not generally in State 3, but certainly in the'' [[OXPHOS capacity|OXPHOS state]] (''P''). | ||
:: >> Update on the '''MitoPedia | :: >> Update on the '''MitoPedia:''' [[MitoPedia: Respiratory states|'''Respiratory states''']] | ||
* '''Hypoxia and high altitude''': [[CH Zurich Lundby C]], [[ | * '''Hypoxia and high altitude''': [[CH Zurich Lundby C]], [[SE Stockholm Boushel RC]], [[AT Innsbruck Gnaiger E]] | ||
:* [[Jacobs 2012 Exp Physiol|Jacobs RA, Boushel RC, Wright-Paradis C, Calbet JA, Robach P, Gnaiger E, Lundby C (2012) Mitochondrial function in human skeletal muscle following high altitude exposure. Exp Physiol | :* [[Jacobs 2012 Exp Physiol|Jacobs RA, Boushel RC, Wright-Paradis C, Calbet JA, Robach P, Gnaiger E, Lundby C (2012) Mitochondrial function in human skeletal muscle following high altitude exposure. Exp Physiol 98:245-55.]] | ||
:* [[Robach 2012 Br J Sports Med|Robach P, Siebenmann C, Jacobs RA, Rasmussen P, Nordsborg N, Pesta D, Gnaiger E, Díaz V, Christ A, Fiedler J, Crivelli N, Secher NH, Pichon A, Maggiorini M, Lundby C (2012) The role of haemoglobin mass on VO<sub>2max</sub> following normobaric 'live high-train low' in endurance-trained athletes. Br J Sports Med Jul 12. | :* [[Robach 2012 Br J Sports Med|Robach P, Siebenmann C, Jacobs RA, Rasmussen P, Nordsborg N, Pesta D, Gnaiger E, Díaz V, Christ A, Fiedler J, Crivelli N, Secher NH, Pichon A, Maggiorini M, Lundby C (2012) The role of haemoglobin mass on VO<sub>2max</sub> following normobaric 'live high-train low' in endurance-trained athletes. Br J Sports Med Jul 12. 46:822-7.]] | ||
:* [[Pesta 2011 Am J Physiol Regul Integr Comp Physiol|Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301: | :* [[Pesta 2011 Am J Physiol Regul Integr Comp Physiol|Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301: R1078–87.]] | ||
:* [[Scandurra 2010 Adv Exp Med Biol|Scandurra FM, Gnaiger E (2010) Cell respiration under hypoxia: Facts and artefacts in mitochondrial oxygen kinetics. Adv Exp Med Biol 662: 7-25.]] | :* [[Scandurra 2010 Adv Exp Med Biol|Scandurra FM, Gnaiger E (2010) Cell respiration under hypoxia: Facts and artefacts in mitochondrial oxygen kinetics. Adv Exp Med Biol 662: 7-25.]] | ||
=== Bioblast alert 2012(07): 2012-10-24 === | === Bioblast alert 2012(07): 2012-10-24 === | ||
* ''' | * '''Bioblast topic''': Publications of historical interest are valued as milestones in science, as sources of understanding currently discussed concepts, and as a reminder that 'nothing' is new (something new is 'nothing'?) >> '''[[Mitochondria and bioblasts: Made history]]''' | ||
* ''' | * '''Bioblast terminology''': [[LEAK respiration]] ''vs.'' [[State 2]]: The resting state of substrate supported respiration without ADP (LEAK state) in contrast to the substrate limited State 2 of [[residual oxygen consumption]] at high ADP concentration: >> [[Chance 1955 J Biol Chem-III|Chance and Williams 1955]]. | ||
: '''MitoPedia | : '''MitoPedia:''' [[MitoPedia: Respiratory states|'''Respiratory states''']] | ||
* [[Bioblast 2012|'''Bioblast 2012''': Conference on Mitochondrial Competence]] in the spirit of [[Gentle Science]]. | * [[Bioblast 2012|'''Bioblast 2012''': Conference on Mitochondrial Competence]] in the spirit of [[Gentle Science]]. | ||
* [[Petition to protect EU science budget]] | * [[Petition to protect EU science budget]] | ||
=== Bioblast alert 2012(08): 2012-12-18 === | === Bioblast alert 2012(08): 2012-12-18 === | ||
* MitoPedia | * MitoPedia: '''[[Substrate control state]]s''' in mitochondrial preparations versus intact cells - new perspectives in OXPHOS analysis. | ||
* | * Bioblast topic: The '''[[Mitochondrial Global Network]] (MitoGlobal)''' aims at providing a WorldWide information platform for scientific mitochondrial organizations. | ||
:* '''[[MitoGlobal_Events_2013|MitoGlobal Events]]''' are listed by Mitochondrial Global Network, providing a comprehensive list of mitochondrial conferences, workshops, and educational programmes. Send us your event to be included in ''MitoGlobal Events''. | :* '''[[MitoGlobal_Events_2013|MitoGlobal Events]]''' are listed by Mitochondrial Global Network, providing a comprehensive list of mitochondrial conferences, workshops, and educational programmes. Send us your event to be included in ''MitoGlobal Events''. | ||
:* We invite organizations with a focus on mitochondrial research and medicine to submit your contact details, to be included in the '''[[MitoGlobal Organizations|List of MitoGlobal Organizations]]'''. | :* We invite organizations with a focus on mitochondrial research and medicine to submit your contact details, to be included in the '''[[MitoGlobal Organizations|List of MitoGlobal Organizations]]'''. | ||
* '''MiP''conference'' 2013 - Comparative Mitochondrial Physiology''' [ | * '''MiP''conference'' 2013 - Comparative Mitochondrial Physiology''' [[MiPNet18.08 MiP2013| MiP2013]], Obergurgl, 2013 September 23 to 27. >>[[MiPNet18.08_MiP2013|MiP2013 Abstracts]] | ||
== Bioblast alert - previous issues == | |||
* [[Bioblast alert 2011]] | |||
[[Category:Gentle Science]] | [[Category:Gentle Science]] | ||
Latest revision as of 12:32, 25 November 2020
Bioblast alert 2012
back to "Bioblast alert" main page
Bioblast alert 2012(01): 2012-02-27
Two exciting publications on mitochondrial p50, apparent excess capacity of cytochrome c oxidase, basal metabolic rate, P/O ratios and ergometric efficiency:
- Larsen FJ, Schiffer TA, Sahlin K, Ekblom B, Weitzberg E, Lundberg JO (2011) Mitochondrial oxygen affinity predicts basal metabolic rate in humans. FASEB J 25: 2843-52.
- Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, Weitzberg E (2011) Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metab 13: 149-59.
Bioblast alert 2012(02): 2012-03-06
- 50 Years ago: Nick Holonyak, considered as the "father of the light-emitting diode", developed the first practical visible-spectrum LED in 1962. Which colour? What is a LED? >>> see MitoPedia: Fluorometry
Mitochondrial dys/function in obesity vs. anorexia:
- Lindfors C, Nilsson IA, Garcia-Roves PM, Zuberi AR, Karimi M, Donahue LR, Roopenian DC, Mulder J, Uhlén M, Ekström TJ, Davisson MT, Hökfelt TG, Schalling M, Johansen JE (2011) Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse. Proc Natl Acad Sci U S A 108: 18108-13.
- Holmstroem MH, Iglesias-Gutierrez E, Zierath JR, Garcia-Roves PM (2012) Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes. Am J Physiol Endocrinol Metab 302: E731-9.
Bioblast alert 2012(03): 2012-03-23 / 2012-04-03
Bioblast topic: Oxygen dependence of ROS production - are permeabilized fibres a valid model?
--> Discussion
Drosophila vs. sandworm: High-resolution respirometry in permeabilized muscle fibres
- Pichaud N, Rioux P, Blier PU (2012) In situ quantification of mitochondrial respiration in permeabilized fibers of a marine invertebrate with low aerobic capacity. Comp Biochem Physiol A Mol Integr Physiol 161: 429-35.
- Pichaud N, Ballard JW, Tanguay RM, Blier PU (2011) Thermal sensitivity of mitochondrial functions in permeabilized muscle fibers from two populations of Drosophila simulans with divergent mitotypes. Am J Physiol Regul Integr Comp Physiol 301: R48-9.
New from the Ballard lab:
Bioblast alert 2012(04): 2012-04-29
- Bioblast topic: Mitochondria - can we decide on a common abbreviation? - or simply call them Bioblasts. --> Mitochondria and Talk:Mitochondria
- Bioblast news: Light in the powerhouse of the cells - a mt-project is the winner of the Houska Award 2012.
- Comparative mt-physiology - life style and training:
Bioblast alert 2012(05): 2012-06-05
- Bioblast topic: Mitochondria and Genetics - the Coactivator PGC-1α
- Bioblast announcement: UMDF: Mitochondrial Medicine 2012 - 2012-June-13 to 16 - Capitol Hill, Bethesda, Washington DC, USA
- Comparison of common bioenergetic analysis methods: Zhang J, Nuebel E, Wisidagama DR, Setoguchi K, Hong JS, Van Horn CM, Imam SS, Vergnes L, Malone CS, Koehler CM, Teitell MA (2012) Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells Nat Protoc 7: 1068-85. >> Continue the discussion
Bioblast alert 2012(06): 2012-07-20
- Bioblast news: Myxothiazol is available again, but what about α-glycerophosphate ?
- >> More information on MitoPedia: Substrates and metabolites
- Bioblast terminology: State 3 - is [ADP] saturating? Not generally in State 3, but certainly in the OXPHOS state (P).
- >> Update on the MitoPedia: Respiratory states
- Hypoxia and high altitude: CH Zurich Lundby C, SE Stockholm Boushel RC, AT Innsbruck Gnaiger E
- Jacobs RA, Boushel RC, Wright-Paradis C, Calbet JA, Robach P, Gnaiger E, Lundby C (2012) Mitochondrial function in human skeletal muscle following high altitude exposure. Exp Physiol 98:245-55.
- Robach P, Siebenmann C, Jacobs RA, Rasmussen P, Nordsborg N, Pesta D, Gnaiger E, Díaz V, Christ A, Fiedler J, Crivelli N, Secher NH, Pichon A, Maggiorini M, Lundby C (2012) The role of haemoglobin mass on VO2max following normobaric 'live high-train low' in endurance-trained athletes. Br J Sports Med Jul 12. 46:822-7.
- Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301: R1078–87.
- Scandurra FM, Gnaiger E (2010) Cell respiration under hypoxia: Facts and artefacts in mitochondrial oxygen kinetics. Adv Exp Med Biol 662: 7-25.
Bioblast alert 2012(07): 2012-10-24
- Bioblast topic: Publications of historical interest are valued as milestones in science, as sources of understanding currently discussed concepts, and as a reminder that 'nothing' is new (something new is 'nothing'?) >> Mitochondria and bioblasts: Made history
- Bioblast terminology: LEAK respiration vs. State 2: The resting state of substrate supported respiration without ADP (LEAK state) in contrast to the substrate limited State 2 of residual oxygen consumption at high ADP concentration: >> Chance and Williams 1955.
- MitoPedia: Respiratory states
- Bioblast 2012: Conference on Mitochondrial Competence in the spirit of Gentle Science.
- Petition to protect EU science budget
Bioblast alert 2012(08): 2012-12-18
- MitoPedia: Substrate control states in mitochondrial preparations versus intact cells - new perspectives in OXPHOS analysis.
- Bioblast topic: The Mitochondrial Global Network (MitoGlobal) aims at providing a WorldWide information platform for scientific mitochondrial organizations.
- MitoGlobal Events are listed by Mitochondrial Global Network, providing a comprehensive list of mitochondrial conferences, workshops, and educational programmes. Send us your event to be included in MitoGlobal Events.
- We invite organizations with a focus on mitochondrial research and medicine to submit your contact details, to be included in the List of MitoGlobal Organizations.
- MiPconference 2013 - Comparative Mitochondrial Physiology MiP2013, Obergurgl, 2013 September 23 to 27. >>MiP2013 Abstracts
