From Bioblast
- high-resolution terminology - matching measurements at high-resolution
ROUTINE respiration
Description
In the living cell, ROUTINE respiration (R) or ROUTINE activity in the physiological coupling state is controlled by cellular energy demand, energy turnover and the degree of coupling to phosphorylation (intrinsic uncoupling and pathological dyscoupling). The conditions for measurement and expression of respiration vary (oxygen flux in state R, JO2R or oxygen flow in state R, IO2R). If these conditions are defined and remain consistent within a given context, then the simple symbol R for respiratory state can be used to substitute the more explicit expression for respiratory activity. R and growth of cells is supported by exogenous substrates in culture media. In media without energy substrates, R depends on endogenous substrates. R cannot be measured in permeabilized cells or isolated mitochondria. R is corrected for residual oxygen consumption (ROX), whereas R´ is the uncorrected apparent ROUTINE respiration or total cellular oxygen consumption of cells including ROX.
Abbreviation: R
Reference: Gnaiger 2020 BEC MitoPathways, Gnaiger 2008 POS
Contributed by Gnaiger E 2019-06-14 (last update); 2010-09-18, edited by Cardoso LHD 2019-04-02.
Coupled energy cycles and and proton circuit of mitochondrial respiration in living cells controlled by aerobic ATP demand in the ROUTINE state of activity. 2[H] indicates the reduced hydrogen equivalents of CHO substrates and electron transfer to oxygen, with a variety of energy substrates from carbohydrates through glycolysis to the tricarboxylic acid cycle (TCA) and glycerophosphate dehydrogenase complex (CGpDH), amino acid oxidation (AAO) and fatty acid oxidation (FAO through the electron transferring flavoprotein complex, CETF). H+out are protons pumped out of the matrix phase to the positive P-phase. Proton flow to the negative matrix phase (H+in) drives the phosphorylation of ADP to ATP. Proton leaks dissipate energy of translocated protons from the positive phase to the negative phase (modified after Gnaiger 2020 BEC MitoPathways).
DatLab oxygen flux: performance and data analysis
- To reach steady state in ROUTINE respiration may require up to 10-15 min, waiting longer is not recommended.
- Guidelines for performing and evaluating respirometric assays: DatLab oxygen flux: performance and data analysis
ROUTINE respiration
- ROUTINE respiration can be evaluated in the following SUIT protocols:
- DL-Protocol for cells that are permeabilized in the O2k chamber (ce-pce): SUIT-001 O2 ce-pce D003; SUIT-001 O2 ce-pce D004 (for PBMC and PLT)
- DL-Protocol for cells that are permeabilized in the O2k chamber (ce-pce): SUIT-002 O2 ce-pce D007; SUIT-002 O2 ce-pce D007a (for PBMC and PLT)
- DL-Protocol for living cells (ce): SUIT-003 O2 ce D009, SUIT-003 O2 ce D037 and SUIT-003 O2 ce D038
- DL-Protocol for coupling control with living cells and cell viability module (ce-pce): SUIT-003 O2 ce-pce D020
- DL-Protocol for cells that are permeabilized in the O2k chamber (ce-pce): SUIT-006 O2 ce-pce D029
- DL-Protocol for cells that are permeabilized in the O2k chamber (ce-pce): SUIT-007 O2 ce-pce D030
- DL-Protocol for cells that are permeabilized in the O2k chamber (ce-pce): SUIT-008 O2 ce-pce D025
- DL-Protocol for cells that are permeabilized in the O2k chamber (ce-pce): SUIT-009 AmR ce-pce D019, and its control SUIT-009 O2 ce-pce D016
- DL-Protocol for evaluation of optimum digitonin concentration for permeabilizing cells: SUIT-010 O2 ce-pce D008
- DL-Protocol for cells that are permeabilized in the O2k chamber (ce-pce): SUIT-012 O2 ce-pce D052
- DL-Protocol for living cells (ce): SUIT-013 AmR ce D023
- ROUTINE respiration can be evaluated in the following SUIT protocols:
SUITbrowser question: ROUTINE respiration
- ROUTINE respiration is assessed by several SUIT protocols. The SUITbrowser can be used to find SUIT protocols for this and other research questions.
Why not 'basal respiration', and what about 'State 3.5'?
- Basal respiration or "basal metabolic rate" is frequently used as LEAK respiration. Importantly, we have to make a clear distinction between (oligomycin-inhibited) LEAK-respiration and physiologically controlled ROUTINE respiration, none of which conform to the physiological definition of basal respiration.
Keywords
The Blue Book 2020
OXPHOS-, ROUTINE-, ET-, and LEAK states; respiratory capacities (P, R, E, L) corrected for residual oxygen consumption Rox.
4-compartmental OXPHOS model. (1) ET capacity E of the noncoupled electron transfer system ETS. OXPHOS capacity P is partitioned into (2) the dissipative LEAK component L, and (3) ADP-stimulated P-L net OXPHOS capacity. (4) If P-L is kinetically limited by a low capacity of the phosphorylation system to utilize the protonmotive force pmF, then the apparent E-P excess capacity is available to drive coupled processes other than phosphorylation P» (ADP to ATP) without competing with P».
(P-L)/P is the OXPHOS P-L control efficiency. The biochemical coupling efficiency is independent of kinetic control by the phosphorylation system when expressed as the E-L coupling efficiency, (E-L)/E. (E-P)/E is the kinetic E-P control efficiency.
- Bioblast links: Coupling control - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
1. Mitochondrial and cellular respiratory rates in coupling-control states
| Respiratory rate | Defining relations | Icon | |
|---|---|---|---|
| OXPHOS capacity | P = P´-Rox |  |
mt-preparations |
| ROUTINE respiration | R = R´-Rox |  |
living cells |
| ET capacity | E = E´-Rox |  |
» Level flow |
| » Noncoupled respiration - Uncoupler | |||
| LEAK respiration | L = L´-Rox |  |
» Static head |
| » LEAK state with ATP | |||
| » LEAK state with oligomycin | |||
| » LEAK state without adenylates | |||
| Residual oxygen consumption Rox | L = L´-Rox | 
|
2. Flux control ratios related to coupling in mt-preparations and living cells
| FCR | Definition | Icon | |
|---|---|---|---|
| L/P coupling-control ratio | L/P |  |
» Respiratory acceptor control ratio, RCR = P/L |
| L/R coupling-control ratio | L/R | 
| |
| L/E coupling-control ratio | L/E |  |
» Uncoupling-control ratio, UCR = E/L (ambiguous) |
| P/E control ratio | P/E | 
| |
| R/E control ratio | R/E |  |
» Uncoupling-control ratio, UCR = E/L |
| net P/E control ratio | (P-L)/E | 
| |
| net R/E control ratio | (R-L)/E | 
|
3. Net, excess, and reserve capacities of respiration
| Respiratory net rate | Definition | Icon |
|---|---|---|
| P-L net OXPHOS capacity | P-L | 
|
| R-L net ROUTINE capacity | R-L | 
|
| E-L net ET capacity | E-L | 
|
| E-P excess capacity | E-P | 
|
| E-R reserve capacity | E-R | 
|
4. Flux control efficiencies related to coupling-control ratios
| Coupling-control efficiency | Definition | Icon | Canonical term | ||
|---|---|---|---|---|---|
| P-L control efficiency | jP-L | = (P-L)/P | = 1-L/P |  |
P-L OXPHOS-flux control efficiency |
| R-L control efficiency | jR-L | = (R-L)/R | = 1-L/R |  |
R-L ROUTINE-flux control efficiency |
| E-L coupling efficiency | jE-L | = (E-L)/E | = 1-L/E |  |
E-L ET-coupling efficiency » Biochemical coupling efficiency |
| E-P control efficiency | jE-P | = (E-P)/E | = 1-P/E |  |
E-P ET-excess flux control efficiency |
| E-R control efficiency | jE-R | = (E-R)/E | = 1-R/E |  |
E-R ET-reserve flux control efficiency |
5. General
- » Basal respiration
- » Cell ergometry
- » Dyscoupled respiration
- » Dyscoupling
- » Electron leak
- » Electron-transfer-pathway state
- » Hyphenation
- » Oxidative phosphorylation
- » Oxygen flow
- » Oxygen flux
- » Permeabilized cells
- » Phosphorylation system
- » Proton leak
- » Proton slip
- » Respiratory state
- » Uncoupling
- » List of publications: ROUTINE
Sort in ascending/descending order by a click on one of the small symbols in squares below. Default sorting: chronological. Empty fields appear first in ascending order.
| Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
|---|---|---|---|---|---|---|---|
| Cruz-Gregorio 2023 Phytother Res | 2023 | Cruz-Gregorio A, Aranda-Rivera AK, Aparicio-Trejo OE, Medina-Campos ON, Sciutto E, Fragoso G, Pedraza-Chaverri J (2023) α-Mangostin induces oxidative damage, mitochondrial dysfunction, and apoptosis in a triple-negative breast cancer model. https://doi.org/10.1002/ptr.7812 | LEAK ROUTINE ET | ROX CIV | Intact cells | Mouse | Endothelial;epithelial;mesothelial cell |
| Antona 2023 Cell Death Discov | 2023 | Antona A, Leo G, Favero F, Varalda M, Venetucci J, Faletti S, Todaro M, Mazzucco E, Soligo E, Saglietti C, Stassi G, Manfredi M, Pelicci G, Corà D, Valente G, Capello D (2023) Targeting lysine-specific demethylase 1 (KDM1A/LSD1) impairs colorectal cancer tumorigenesis by affecting cancer cells stemness, motility, and differentiation. https://doi.org/10.1038/s41420-023-01502-1 | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Mendoza-Fuentes 2023 PeerJ | 2023 | Mendoza-Fuentes A, González-Burgos E, Aparicio Trejo OE, Delgado-Lamas G, Rodríguez-Chávez JL, Pedraza-Chaverri J, Gómez-Serranillos MP, Araiza-Olivera D (2023) The cytotoxicity effect of 7-hydroxy-3,4-dihydrocadalene from Heterotheca inuloides and semisynthetic cadalenes derivates towards breast cancer cells: involvement of oxidative stress-mediated apoptosis. https://doi.org/10.7717/peerj.15586 | LEAK ROUTINE | ROX | Intact cells | Human | |
| Stampley 2023 Physiol Rep | 2023 | Stampley JE, Cho E, Wang H, Theall B, Johannsen NM, Spielmann G, Irving BA (2023) Impact of maximal exercise on immune cell mobilization and bioenergetics. https://doi.org/10.14814/phy2.15753 | LEAK ROUTINE OXPHOS ET | N NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Oliveira 2023 J Biol Chem | 2023 | Oliveira AG, Oliveira LD, Cruz MV, Guimarães DSPSF, Lima TI, BC Santos-Fávero, Luchessi AD, BA Pauletti, Leme AP, Bajgelman MC, Afonso J, Regitano LCA, Carvalho HF, Carneiro EM, Kobarg J, Perissi V, Auwerx J, Silveira LR (2023) Interaction between poly-A binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response. https://doi.org/10.1016/j.jbc.2023.104702 | LEAK ROUTINE ET | ROX | Intact cells | ||
| Pereyra 2023 Am J Physiol Gastrointest Liver Physiol | 2023 | Pereyra AS, McLaughlin KL, Buddo KA, Ellis JM (2023) Medium-chain fatty acid oxidation is independent of L-carnitine in liver and kidney but not in heart and skeletal muscle. https://doi.org/10.1152/ajpgi.00105.2023 | LEAK ROUTINE OXPHOS | F N | Homogenate | Mouse | Heart Skeletal muscle Liver Kidney |
| Diaz 2023 Front Mol Biosci | 2023 | Diaz EC, Adams SH, Weber JL, Cotter M, Børsheim E (2023) Elevated LDL-C, high blood pressure, and low peak V˙O2 associate with platelet mitochondria function in children-The Arkansas Active Kids Study. Front Mol Biosci 10:1136975. https://doi.org/10.3389/fmolb.2023.1136975 | LEAK ROUTINE ET | N S | Permeabilized cells | Human | Blood cells Platelet |
| Yang 2023 Cell Death Discov | 2023 | Yang H, Gao Y, Xu D, Xu K, Liang SQ, Yang Z, Scherz A, Hall SRR, Forster S, Berezowska S, Yao F, Ochsenbein AF, Marti TM, Kocher GJ, Schmid RA, Dorn P, Peng RW (2023) MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. https://doi.org/10.1038/s41420-023-01307-2 | ROUTINE | Intact cells | Human | Lung;gill Endothelial;epithelial;mesothelial cell | |
| Kamienieva 2023 Biochim Biophys Acta Mol Basis Dis | 2023 | Kamienieva I, Charzyńska A, Duszyński J, Malińska D, Szczepanowska J (2023) In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts. https://doi.org/10.1016/j.bbadis.2023.166787 | LEAK ROUTINE ET | Intact cells | Human | Fibroblast | |
| Silva Dias Vieira 2023 PLoS Negl Trop Dis | 2023 | Silva Dias Vieira C, Pinheiro Aguiar R, de Almeida Nogueira NP, Costa Dos Santos Junior G, Paes MC (2023) Glucose metabolism sustains heme-induced Trypanosoma cruzi epimastigote growth in vitro. https://doi.org/10.1371/journal.pntd.0011725 | ROUTINE ET | ROX | Intact cells | Protists | |
| Bellar 2023 Clin Transl Med | 2023 | Bellar A, Welch N, Dasarathy J, Attaway A, Musich R, Kumar A, Sekar J, Mishra S, Sandlers Y, Streem D, Nagy LE, Dasarathy S (2023) Peripheral blood mononuclear cell mitochondrial dysfunction in acute alcohol-associated hepatitis. https://doi.org/10.1002/ctm2.1276 | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Ebanks 2023 PLoS One | 2023 | Ebanks B, Kwiecinska P, Moisoi N, Chakrabarti L (2023) A method to assess the mitochondrial respiratory capacity of complexes I and II from frozen tissue using the Oroboros O2k-FluoRespirometer. https://doi.org/10.1371/journal.pone.0276147 | ROUTINE LEAK | N S NS ROX | Homogenate | Mouse Drosophila | Skeletal muscle |
| Calabria 2023 Biomedicines | 2023 | Calabria E, Muollo V, Cavedon V, Capovin T, Saccenti L, Passarotti F, Ghiotto L, Milanese C, Gelati M, Rudi D, Salvagno GL, Lippi G, Tam E, Schena F, Pogliaghi S (2023) Type 2 diabetes related mitochondrial defects in peripheral mononucleated blood cells from overweight postmenopausal women. https://doi.org/10.3390/biomedicines11010121 | LEAK ROUTINE OXPHOS ET | N NS ROX S | Permeabilized cells Intact cells | Human | Blood cells |
| Martell 2023 Acta Neuropathol Commun | 2023 | Martell E, Kuzmychova H, Senthil H, Kaul E, Chokshi CR, Venugopal C, Anderson CM, Singh SK, Sharif T (2023) Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations. https://doi.org/10.1186/s40478-023-01604-y | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
| Robertson 2023 J Cell Sci | 2023 | Robertson GL, Riffle S, Patel M, Bodnya C, Marshall A, Beasley HK, Garza-Lopez E, Shao J, Vue Z, Hinton A, Stoll MS, de Wet S, Theart RP, Chakrabarty RP, Loos B, Chandel NS, Mears JA, Gama V (2023) DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs. https://doi.org/10.1242/jcs.260370 | LEAK ROUTINE OXPHOS ET | F N S DQ CIV NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Cortes 2023 Nat Commun | 2023 | Cortés M, Brischetto A, Martinez-Campanario MC, Ninfali C, Domínguez V, Fernández S, Celis R, Esteve-Codina A, Lozano JJ, Sidorova J, Garrabou G, Siegert AM, Enrich C, Pintado B, Morales-Ruiz M, Castro P, Cañete JD, Postigo A (2023) Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation. https://doi.org/10.1038/s41467-023-42277-4 | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Pavluch 2023 Sci Rep | 2023 | Pavluch V, Engstová H, Špačková J, Ježek P (2023) Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells. https://doi.org/10.1038/s41598-023-27985-7 | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
| Kienzle 2023 BMC Biol | 2023 | Kienzle L, Bettinazzi S, Choquette T, Brunet M, Khorami HH, Jacques JF, Moreau M, Roucou X, Landry CR, Angers A, Breton S (2023) A small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics. https://doi.org/10.1186/s12915-023-01609-y | LEAK ROUTINE OXPHOS ET | N CIV NS ROX | Permeabilized cells Intact cells | Human | HEK HeLa |
| Ren 2023 Cell Discov | 2023 | Ren X, Yan J, Zhao Q, Bao X, Han X, Zheng C, Zhou Y, Chen L, Wang B, Yang L, Lin X, Liu D, Lin Y, Li M, Fang H, Lu Z, Lyu J (2023) The Fe-S cluster assembly protein IscU2 increases α-ketoglutarate catabolism and DNA 5mC to promote tumor growth. https://doi.org/10.1038/s41421-023-00558-8 | LEAK ROUTINE ET | Intact cells | Human | Islet cell;pancreas;thymus | |
| Martell 2023 Nat Commun | 2023 | Martell E, Kuzmychova H, Kaul E, Senthil H, Chowdhury SR, Morrison LC, Fresnoza A, Zagozewski J, Venugopal C, Anderson CM, Singh SK, Banerji V, Werbowetski-Ogilvie TE, Sharif T (2023) Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma. https://doi.org/10.1038/s41467-023-38049-9 | LEAK ROUTINE OXPHOS ET | N S CIV ROX | Permeabilized cells Intact cells | Human | Nervous system |
| Godtliebsen 2023 Autophagy | 2023 | Godtliebsen G, Larsen KB, Bhujabal Z, Opstad IS, Nager M, Punnakkal AR, Kalstad TB, Olsen R, Lund T, Prasad DK, Agarwal K, Myrmel T, Birgisdottir AB (2023) High-resolution visualization and assessment of basal and OXPHOS-induced mitophagy in H9c2 cardiomyoblasts. https://doi.org/10.1080/15548627.2023.2230837 | LEAK ROUTINE ET | ROX | Intact cells | Rat | Heart |
| Duran-Gueell 2023 FASEB J | 2023 | Duran-Güell M, Garrabou G, Flores-Costa R, Casulleras M, López-Vicario C, Zhang IW, Cantó-Santos J, Contreras BJ, Sánchez-Rodríguez MB, Romero-Grimaldo B, Horrillo R, Costa M, Arroyo V, Clària J (2023) Essential role for albumin in preserving liver cells from TNFα-induced mitochondrial injury. https://doi.org/10.1096/fj.202201526r | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Liver |
| Gonnot 2023 Nat Commun | 2023 | Gonnot F, Boulogne L, Brun C, Dia M, Gouriou Y, Bidaux G, Chouabe C, Crola Da Silva C, Ducreux S, Pillot B, Kaczmarczyk A, Leon C, Chanon S, Perret C, Sciandra F, Dargar T, Gache V, Farhat F, Sebbag L, Bochaton T, Thibault H, Ovize M, Paillard M, Gomez L (2023) SERCA2 phosphorylation at serine 663 is a key regulator of Ca2+ homeostasis in heart diseases. https://doi.org/10.1038/s41467-023-39027-x | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Heart |
| Mioc 2023 Molecules | 2023 | Mioc M, Mioc A, Racoviceanu R, Ghiulai R, Prodea A, Milan A, Barbu Tudoran L, Oprean C, Ivan V, Șoica C (2023) The antimelanoma biological assessment of triterpenic acid functionalized gold nanoparticles. https://doi.org/10.3390/molecules28010421 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Shi 2023 Redox Biol | 2023 | Shi L, Tao Z, Zheng L, Yang J, Hu X, Scott K, de Kloet A, Krause E, Collins JF, Cheng Z (2023) FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway. https://doi.org/10.1016/j.redox.2023.102727 | LEAK ET ROUTINE | F | Intact cells | Mouse | Fat |
| Fisher-Wellman 2023 Cancers (Basel) | 2023 | Fisher-Wellman KH, Kassai M, Hagen JT, Neufer PD, Kester M, Loughran TP Jr, Chalfant CE, Feith DJ, Tan SF, Fox TE, Ung J, Fabrias G, Abad JL, Sharma A, Golla U, Claxton DF, Shaw JJP, Bhowmick D, Cabot MC (2023) Simultaneous inhibition of ceramide hydrolysis and glycosylation synergizes to corrupt mitochondrial respiration and signal caspase driven cell death in drug-resistant acute myeloid leukemia. https://doi.org/10.3390/cancers15061883 | LEAK ROUTINE ET | F N NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Pacheco-Fuentes 2023 Oecologia | 2023 | Pacheco-Fuentes H, Ton R, Griffith SC (2023) Short- and long-term consequences of heat exposure on mitochondrial metabolism in zebra finches (Taeniopygia castanotis). https://doi.org/10.1007/s00442-023-05344-7 | LEAK ROUTINE OXPHOS ET | N ROX | Intact cells | Birds | Blood cells |
| Fisar 2023 Biomedicines | 2023 | Fišar Z, Hroudová J, Zvěřová M, Jirák R, Raboch J, Kitzlerová E (2023) Age-dependent alterations in platelet mitochondrial respiration. https://doi.org/10.3390/biomedicines11061564 | LEAK ROUTINE ET | ROX | Intact cells | Human | Platelet |
| Nord 2023 FASEB J | 2023 | Nord A, Chamkha I, Elmér E (2023) A whole blood approach improves speed and accuracy when measuring mitochondrial respiration in intact avian blood cells. https://doi.org/10.1096/fj.202201749r | LEAK ROUTINE ET | ROX | Intact cells | Birds | Blood cells |
| Lu 2022 J Cosmet Dermatol | 2022 | Lu Q, Zou LF, Gao YZ, Ye T, Li MJ, Zhang YK, Liang B, Sun W, Xing DM (2022) Liquiritigenin reverses skin aging by inhibiting UV-induced mitochondrial uncoupling and excessive energy consumption. https://doi.org/10.1111/jocd.15506 | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Leggio 2022 Adv Healthc Mater | 2022 | Leggio L, L'Episcopo F, Magrì A, Ulloa-Navas MJ, Paternò G, Vivarelli S, Bastos CAP, Tirolo C, Testa N, Caniglia S, Risiglione P, Pappalardo F, Serra A, García-Tárraga P, Faria N, Powell JJ, Peruzzotti-Jametti L, Pluchino S, García-Verdugo JM, Messina A, Marchetti B, Iraci N (2022) Small extracellular vesicles secreted by nigrostriatal astrocytes rescue cell death and preserve mitochondrial function in Parkinson's disease. https://doi.org/10.1002/adhm.202201203 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
| Weiss 2022 J Cell Mol Med | 2022 | Weiss SL, Zhang D, Farooqi S, Wallace DC (2022) Sodium butyrate reverses lipopolysaccharide-induced mitochondrial dysfunction in lymphoblasts. https://doi.org/10.1111/jcmm.17342 | ROUTINE OXPHOS ET | N | Intact cells | Other cell lines | |
| Heichler 2022 BEC | 2022 | Heichler C, Nagy M, Wolf P (2022) Evaluation of hepatotoxic effects of acetaminophen on HepG2 cells by parallel real-time monitoring in a multi-sensor analysis platform for automated cell-based assays. https://doi.org/10.26124/bec:2022-0006 | ROUTINE | Intact cells | Human | Liver Other cell lines | |
| Donnelly 2022 BEC | 2022 | Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlódi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioenerg Commun 2022.12.v2. https://doi.org/10.26124/bec:2022-0012.v2 | ROUTINE | ||||
| Siewiera 2022 Int J Mol Sci | 2022 | Siewiera K, Labieniec-Watala M, Kassassir H, Wolska N, Polak D, Watala C (2022) Potential role of mitochondria as modulators of blood platelet activation and reactivity in diabetes and effect of metformin on blood platelet bioenergetics and platelet activation. https://doi.org/10.3390/ijms23073666 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Rat | Platelet |
| Heichler 2022 MitoFit | 2022 | Heichler C, Nagy M, Wolf P (2022) Evaluation of hepatotoxic effects of acetaminophen on HepG2 cells by parallel real-time monitoring in a multi-sensor analysis platform for automated cell-based assays. https://doi.org/10.26124/mitofit:2022-0006 — 2022-07-06 published in Bioenerg Commun 2022.6. | ROUTINE | Intact cells | Human | Liver Other cell lines | |
| Zhu 2022 Metabolism | 2022 | Zhu JY, Chen M, Mu WJ, Luo HY, Guo L (2022) Higd1a facilitates exercise-mediated alleviation of fatty liver in diet-induced obese mice. https://doi.org/10.1016/j.metabol.2022.155241 | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Liver |
| Tremmel 2022 Sci Rep | 2022 | Tremmel DM, Sackett SD, Feeney AK, Mitchell SA, Schaid MD, Polyak E, Chlebeck PJ, Gupta S, Kimple ME, Fernandez LA, Odorico JS (2022) A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment. https://doi.org/10.1038/s41598-022-11085-z | LEAK ROUTINE ET | ROX | Intact cells | Human | Islet cell;pancreas;thymus |
| Long 2022 Cell Commun Signal | 2022 | Long C, Guo R, Han R, Li K, Wan Y, Xu J, Gong X, Zhao Y, Yao X, Liu J (2022) Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells. https://doi.org/10.1186/s12964-022-00916-1 | LEAK ROUTINE ET | ROX | Intact cells | Human | Macrophage-derived |
| Hansen 2022 Free Radic Biol Med | 2022 | Hansen C, Møller S, Ehlers T, Wickham KA, Bangsbo J, Gliemann L, Hellsten Y (2022) Redox balance in human skeletal muscle-derived endothelial cells - Effect of exercise training. https://doi.org/10.1016/j.freeradbiomed.2021.12.265 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Billingham 2022 Nat Immunol | 2022 | Billingham LK, Stoolman JS, Vasan K, Rodriguez AE, Poor TA, Szibor M, Jacobs HT, Reczek CR, Rashidi A, Zhang P, Miska J, Chandel NS (2022) Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation. Nat Immunol 23:692-704. https://doi.org/10.1038/s41590-022-01185-3 | ROUTINE | ||||
| Tilokani 2022 Sci Adv | 2022 | Tilokani L, Russell FM, Hamilton S, Virga DM, Segawa M, Paupe V, Gruszczyk AV, Protasoni M, Tabara LC, Johnson M, Anand H, Murphy MP, Hardie DG, Polleux F, Prudent J (2022) AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology. https://doi.org/10.1126/sciadv.abo7956 | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
| Munoz-Pujol 2022 Brain Pathol | 2022 | Muñoz-Pujol G, Ortigoza-Escobar JD, Paredes-Fuentes AJ, Jou C, Ugarteburu O, Gort L, Yubero D, García-Cazorla A, O'Callaghan M, Campistol J, Muchart J, Yépez VA, Gusic M, Gagneur J, Prokisch H, Artuch R, Ribes A, Urreizti R, Tort F (2022) Leigh syndrome is the main clinical characteristic of PTCD3 deficiency. https://doi.org/10.1111/bpa.13134 | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
| Torres-Quesada 2022 MitoFit | 2022 | Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Human Plasma-Like Media fine-tune mitochondrial function and alter drug sensitivity in cancer cell lines. https://doi.org/10.26124/mitofit:2022-0008 — 2022-08-13 published in https://doi.org/10.3390/cancers14163917 | ROUTINE LEAK ET | ROX | Intact cells | Human | Other cell lines |
| Gvozdjakova 2022 Environ Sci Pollut Res Int | 2022 | Gvozdjáková A, Sumbalová Z, Kucharská J, Rausová Z, Kovalčíková E, Takácsová T, Navas P, López-Lluch G, Mojto V, Palacka P (2022) Mountain spa rehabilitation improved health of patients with post-COVID-19 syndrome: pilot study. https://doi.org/10.1007/s11356-022-22949-2 | LEAK ROUTINE OXPHOS ET | N NS | Permeabilized cells Intact cells | Human | Platelet |
| Della Noce 2022 J Biol Chem | 2022 | Della Noce B, Martins da Silva R, de Carvalho Uhl MV, Konnai S, Ohashi K, Calixto C, Arcanjo A, de Abreu LA, de Carvalho SS, da Silva Vaz I Jr, Logullo C (2022) Redox imbalance induces remodeling of glucose metabolism in Rhipicephalus microplus embryonic cell line. https://doi.org/10.1016/j.jbc.2022.101599 | LEAK ROUTINE ET | ROX | Intact cells | Chelicerates | Other cell lines |
| Laehteenmaeki 2022 Physiol Rep | 2022 | Lähteenmäki EI, Koski M, Koskela I, Lehtonen E, Kankaanpää A, Kainulainen H, Walker S, Lehti M (2022) Resistance exercise with different workloads have distinct effects on cellular respiration of peripheral blood mononuclear cells. https://doi.org/10.14814/phy2.15394 | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Zhou 2022 J Hum Genet | 2022 | Zhou X, Lou X, Zhou Y, Xie Y, Han X, Dong Q, Ying X, Laurentinah MR, Zhang L, Chen Z, Li D, Fang H, Lyu J, Yang Y, Wang Y (2022) Novel biallelic mutations in TMEM126B cause splicing defects and lead to Leigh-like syndrome with severe complex I deficiency. https://doi.org/10.1038/s10038-022-01102-4 | LEAK ROUTINE ET | Intact cells | Human | Lymphocyte | |
| Risiglione 2022 Life (Basel) | 2022 | Risiglione P, Cubisino SAM, Lipari CLR, De Pinto V, Messina A, Magrì A (2022) α-Synuclein A53T promotes mitochondrial proton gradient dissipation and depletion of the organelle respiratory reserve in a neuroblastoma cell line. https://doi.org/10.3390/life12060894 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
| Branicky 2022 Sci Adv | 2022 | Branicky R, Wang Y, Khaki A, Liu JL, Kramer-Drauberg M, Hekimi S (2022) Stimulation of RAS-dependent ROS signaling extends longevity by modulating a developmental program of global gene expression. https://doi.org/10.1126/sciadv.adc9851 | ROUTINE | Intact organism | Caenorhabditis elegans | ||
| Crowder 2022 Islets | 2022 | Crowder JJ, Zeng Z, Novak AN, Alves NJ, Linnemann AK (2022) Stabilization protects islet integrity during respirometry in the Oroboros Oxygraph-2K analyzer. Islets 14:128-38. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Islet cell;pancreas;thymus |
| Zhang 2022 Ecotoxicol Environ Saf | 2022 | Zhang Y, Yuan F, Li P, Gu J, Han J, Ni Z, Liu F (2022) Resveratrol inhibits HeLa cell proliferation by regulating mitochondrial function. https://doi.org/10.1016/j.ecoenv.2022.113788 | LEAK ROUTINE ET | ROX | Intact cells | Human | HeLa |
| Bina 2022 Mol Cell Biochem | 2022 | Bînă AM, Aburel OM, Avram VF, Lelcu T, Lința AV, Chiriac DV, Mocanu AG, Bernad E, Borza C, Craina ML, Popa ZL, Muntean DM, Crețu OM (2022) Impairment of mitochondrial respiration in platelets and placentas: a pilot study in preeclamptic pregnancies. https://doi.org/10.1007/s11010-022-04415-2 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human | Genital Platelet |
| Zdrazilova 2022 PLOS ONE | 2022 | Zdrazilova L, Hansikova H, Gnaiger E (2022) Comparable respiratory activity in attached and suspended human fibroblasts. https://doi.org/10.1371/journal.pone.0264496 | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
| Fets 2022 Commun Biol | 2022 | Fets L, Bevan N, Nunes PM, Campos S, Dos Santos MS, Sherriff E, MacRae JI, House D, Anastasiou D (2022) MOG analogues to explore the MCT2 pharmacophore, α-ketoglutarate biology and cellular effects of N-oxalylglycine. https://doi.org/10.1038/s42003-022-03805-y | ROUTINE | Intact cells | Rat | Islet cell;pancreas;thymus | |
| Ilha 2022 Cell Biol Int | 2022 | Ilha M, Meira Martins LA, da Silveira Moraes K, Dias CK, Thomé MP, Petry F, Rohden F, Borojevic R, Trindade VMT, Klamt F, Barbé-Tuana F, Lenz G, Guma FCR (2022) Caveolin-1 influences mitochondrial plasticity and function in hepatic stellate cell activation. https://doi.org/10.1002/cbin.11876 | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Liver |
| Dias 2022 Free Radic Biol Med | 2022 | Dias C, Lourenço CF, Laranjinha J, Ledo A (2022) Modulation of oxidative neurometabolism in ischemia/reperfusion by nitrite. https://doi.org/10.1016/j.freeradbiomed.2022.11.021 | ROUTINE OXPHOS ET | N S ROX | Permeabilized tissue Intact cells | Rat | Nervous system |
| Chojnacka 2022 Mol Biol Cell | 2022 | Chojnacka KJ, Elancheliyan P, Mussulini BHM, Mohanraj K, Callegari S, Gosk A, Banach T, Góral T, Szczepanowska K, Rehling P, Serwa RA, Chacinska A (2022) Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III-specific assembly factor in mitochondria. https://doi.org/10.1091/mbc.e21-03-0143 | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Intact cells | Human | HEK |
| Karavyraki 2022 MitoFit | 2022 | Karavyraki M, Gnaiger E, Porter RK (2022) A comparison of bioenergetics in human tongue pre-cancerous dysplastic oral keratinocytes and squamous cancer cells. https://doi.org/10.26124/mitofit:2022-0022 — 2022-11-11 published in Bioenerg Commun 2022.11. | LEAK ROUTINE ET | S ROX | Permeabilized cells | Human | |
| Vacurova 2022 Nat Commun | 2022 | Vacurova E, Trnovska J, Svoboda P, Skop V, Novosadova V, Reguera DP, Petrezselyová S, Piavaux B, Endaya B, Spoutil F, Zudova D, Stursa J, Melcova M, Bielcikova Z, Werner L, Prochazka J, Sedlacek R, Huttl M, Hubackova SS, Haluzik M, Neuzil J (2022) Mitochondrially targeted tamoxifen alleviates markers of obesity and type 2 diabetes mellitus in mice. https://doi.org/10.1038/s41467-022-29486-z | LEAK ROUTINE | Intact cells | Mouse | Fat | |
| Jedlicka 2022a Physiol Res | 2022 | Jedlička J, Tůma Z, Razak K, Kunc R, Kala A, Proskauer Pena S, Lerchner T, Ježek K, Kuncová J (2022) Impact of aging on mitochondrial respiration in various organs. https://doi.org/10.33549/physiolres.934995 | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue Homogenate Intact cells | Rat | Heart Skeletal muscle Nervous system Liver Kidney Platelet |
| Nath 2022 Cell Rep | 2022 | Nath AS, Parsons BD, Makdissi S, Chilvers RL, Mu Y, Weaver CM, Euodia I, Fitze KA, Long J, Scur M, Mackenzie DP, Makrigiannis AP, Pichaud N, Boudreau LH, Simmonds AJ, Webber CA, Derfalvi B, Hammon Y, Rachubinski RA, Di Cara F (2022) Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responses . Cell Rep 38:110433. | LEAK ROUTINE OXPHOS ET | N Gp CIV ROX | Permeabilized cells Intact cells | ||
| Belal 2022 Biomedicines | 2022 | Belal S, Goudenège D, Bocca C, Dumont F, Chao De La Barca JM, Desquiret-Dumas V, Gueguen N, Geffroy G, Benyahia R, Kane S, Khiati S, Bris C, Aranyi T, Stockholm D, Inisan A, Renaud A, Barth M, Simard G, Reynier P, Letournel F, Lenaers G, Bonneau D, Chevrollier A, Procaccio V (2022) Glutamate-induced deregulation of krebs cycle in mitochondrial encephalopathy lactic acidosis syndrome stroke-like episodes (MELAS) syndrome is alleviated by ketone body exposure. https://doi.org/10.3390/biomedicines10071665 | LEAK ROUTINE ET | Intact cells | Human | Neuroblastoma | |
| Torres-Quesada 2022 Cancers (Basel) | 2022 | Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Physiological cell culture media tune mitochondrial bioenergetics and drug sensitivity in cancer cell models. https://doi.org/10.3390/cancers14163917 | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
| Scrima 2022 Stem Cell Res Ther | 2022 | Scrima R, Agriesti F, Pacelli C, Piccoli C, Pucci P, Amoresano A, Cela O, Nappi L, Tataranni T, Mori G, Formisano P, Capitanio N (2022) Myoglobin expression by alternative transcript in different mesenchymal stem cells compartments. https://doi.org/10.1186/s13287-022-02880-6 | ROUTINE | ROX | Intact cells | Human | Stem cells |
| Sumbalova 2022 Front Mol Biosci | 2022 | Sumbalová Z, Kucharská J, Rausová Z, Palacka P, Kovalčíková E, Takácsová T, Mojto V, Navas P, Lopéz-Lluch G, Gvozdjáková A (2022) Reduced platelet mitochondrial respiration and oxidative phosphorylation in patients with post COVID-19 syndrome are regenerated after spa rehabilitation and targeted ubiquinol therapy. https://doi.org/10.3389/fmolb.2022.1016352 | LEAK ROUTINE OXPHOS ET | N NS | Permeabilized cells Intact cells | Human | Platelet |
| Donnelly 2022 MitoFit Hypoxia | 2022 | Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. https://doi.org/10.26124/mitofit:2022-0025.v2 — 2022-11-14 published in Bioenerg Commun 2022.12. | ROUTINE | ||||
| Karavyraki 2022 BEC | 2022 | Karavyraki M, Gnaiger E, Porter RK (2022) Bioenergetics in human tongue pre-cancerous dysplastic oral keratinocytes and squamous cancer cells. https://doi.org/10.26124/bec:2022-0011 | LEAK ROUTINE ET | S ROX | Permeabilized cells | Human | |
| Peugnet 2022 Antioxidants (Basel) | 2022 | Peugnet V, Chwastyniak M, Mulder P, Lancel S, Bultot L, Fourny N, Renguet E, Bugger H, Beseme O, Loyens A, Heyse W, Richard V, Amouyel P, Bertrand L, Pinet F, Dubois-Deruy E (2022) Mitochondrial-targeted therapies require mitophagy to prevent oxidative stress induced by SOD2 inactivation in hypertrophied cardiomyocytes. https://doi.org/10.3390/antiox11040723 | LEAK ROUTINE ET | ROX | Intact cells | Rat | Heart |
| Fischer 2022 Metabolites | 2022 | Fischer C, Valente de Souza L, Komlódi T, Garcia-Souza LF, Volani C, Tymoszuk P, Demetz E, Seifert M, Auer K, Hilbe R, Brigo N, Petzer V, Asshoff M, Gnaiger E, Weiss G (2022) Mitochondrial respiration in response to iron deficiency anemia. Comparison of peripheral blood mononuclear cells and liver. https://doi.org/10.3390/metabo12030270 | LEAK ROUTINE OXPHOS ET | N S NS Other combinations ROX | Permeabilized cells Homogenate | Rat | Liver Blood cells |
| Nadeu 2022 Nat Med | 2022 | Nadeu F, Royo R, Massoni-Badosa R, Playa-Albinyana H, Garcia-Torre B, Duran-Ferrer M, Dawson KJ, Kulis M, Diaz-Navarro A, Villamor N, Melero JL, Chapaprieta V, Dueso-Barroso A, Delgado J, Moia R, Ruiz-Gil S, Marchese D, Giró A, Verdaguer-Dot N, Romo M, Clot G, Rozman M, Frigola G, Rivas-Delgado A, Baumann T, Alcoceba M, González M, Climent F, Abrisqueta P, Castellví J, Bosch F, Aymerich M, Enjuanes A, Ruiz-Gaspà S, López-Guillermo A, Jares P, Beà S, Capella-Gutierrez S, Gelpí JL, López-Bigas N, Torrents D, Campbell PJ, Gut I, Rossi D, Gaidano G, Puente XS, Garcia-Roves PM, Colomer D, Heyn H, Maura F, Martín-Subero JI, Campo E (2022) Detection of early seeding of Richter transformation in chronic lymphocytic leukemia. https://doi.org/10.1038/s41591-022-01927-8 | LEAK ROUTINE ET | ROX | Intact cells | Human | Lymphocyte Blood cells |
| Weiss 2022 Shock | 2022 | Weiss SL, Henrickson SE, Lindell RB, Sartori LF, Zhang D, Bush J, Farooqi S, Starr J, Deutschman CS, McGowan FX Jr, Becker L, Tuluc F, Wherry EJ, Picard M, Wallace DC (2022) Influence of immune cell subtypes on mitochondrial measurements in peripheral blood mononuclear cells from children with sepsis. Shock 57:630-8. https://doi.org/10.1097/SHK.0000000000001903 | ROUTINE | Intact cells | Human | Blood cells | |
| Sun 2021 J Genet Genomics | 2021 | Sun Y, Wei X, Fang F, Shen Y, Wei H, Li J, Ye X, Zhan Y, Ye X, Liu X, Yang W, Li Y, Geng X, Huang X, Ruan Y, Qin Z, Yi S, Lyu J, Fang H, Yu Y (2021) HPDL deficiency causes a neuromuscular disease by impairing the mitochondrial respiration. J Genet Genomics 48:727-36. | LEAK ROUTINE ET | N S NS | Permeabilized cells Intact cells | Human | HeLa Lymphocyte |
| Fang 2021 Cell Rep | 2021 | Fang H, Ye X, Xie J, Li Y, Li H, Bao X, Yang Y, Lin Z, Jia M, Han Q, Zhu J, Li X, Zhao Q, Yang Y, Lyu J (2021) A membrane arm of mitochondrial complex I sufficient to promote respirasome formation. Cell Rep 35:108963. | LEAK ROUTINE OXPHOS ET | N S | Permeabilized cells Intact cells | ||
| James 2021 Nat Commun | 2021 | James OJ, Vandereyken M, Marchingo JM, Singh F, Bray SE, Wilson J, Love AG, Swamy M (2021) IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes. Nat Commun 12:4290. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Mouse | Lymphocyte |
| Hoppel 2021 Cells | 2021 | Hoppel F, Garcia-Souza LF, Kantner-Rumplmair W, Burtscher M, Gnaiger E, Pesta D, Calabria E (2021) Human platelet mitochondrial function reflects systemic mitochondrial alterations: a protocol for application in field studies. https://doi.org/10.3390/cells10082088 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet |
| Palacka 2021 Int J Mol Sci | 2021 | Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. https://doi.org/10.3390/ijms23010388 | LEAK ROUTINE OXPHOS ET | F N S Gp NS ROX | Permeabilized cells Intact cells | Human | Platelet |
| Wigner 2021 Sci Rep | 2021 | Wigner P, Zielinski K, Labieniec-Watala M, Marczak A, Szwed M (2021) Doxorubicin-transferrin conjugate alters mitochondrial homeostasis and energy metabolism in human breast cancer cells. Sci Rep 11:4544. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Other cell lines |
| Willis 2021 Sci Rep | 2021 | Willis JR, Hickey AJR, Devaux JBL (2021) Thermally tolerant intertidal triplefin fish (Tripterygiidae) sustain ATP dynamics better than subtidal species under acute heat stress. Sci Rep 11:11074. | LEAK OXPHOS ET ROUTINE | N ROX NS | Homogenate | Fishes | Nervous system |
| Chowdhury 2021 Cancers (Basel) | 2021 | Chowdhury SR, Peltier C, Hou S, Singh A, Johnston JB, Gibson SB, Marshall A, Banerji V (2021) Ex vivo mitochondrial respiration parallels biochemical response to ibrutinib in CLL cells. Cancers (Basel) 13:E354. | LEAK ROUTINE ET | ROX | Intact cells | Human | Lymphocyte |
| Hester 2021 Pharmaceutics | 2021 | Hester S, Ferenz KB, Eitner S, Langer K (2021) Development of a lyophilization process for long-term storage of albumin-based perfluorodecalin-filled artificial oxygen carriers. Pharmaceutics 13:584. | ROUTINE | Intact cells | Saccharomyces cerevisiae | ||
| Ferreira 2021 Redox Biol | 2021 | Ferreira JJ, Cassina A, Irigoyen P, Ford M, Pietroroia S, Peramsetty N, Radi R, Santi CM, Sapiro R (2021) Increased mitochondrial activity upon CatSper channel activation is required for mouse sperm capacitation. https://doi.org/10.1016/j.redox.2021.102176 | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Genital |
| Acin-Perez 2021 Life (Basel) | 2021 | Acin-Perez R, Benincá C, Shabane B, Shirihai OS, Stiles L (2021) Utilization of human samples for assessment of mitochondrial bioenergetics: gold standards, limitations, and future perspectives. Life (Basel) 11:949. doi: 10.3390/life11090949 | LEAK ROUTINE OXPHOS ET | Intact organ Permeabilized cells Permeabilized tissue Intact cells | Human | Skeletal muscle Blood cells Fibroblast Platelet | |
| Honecker 2021 Int J Obes (Lond) | 2021 | Honecker J, Weidlich D, Heisz S, Lindgren CM, Karampinos DC, Claussnitzer M, Hauner H (2021) A distribution-centered approach for analyzing human adipocyte size estimates and their association with obesity-related traits and mitochondrial function. Int J Obes (Lond) [Ephub ahead of print]. | LEAK ROUTINE OXPHOS ET | Intact cells | Human | Fat | |
| Scheffer 2021 Brain Commun | 2021 | Scheffer DDL, Freitas FC, Aguiar AS Jr, Ward C, Guglielmo LGA, Prediger RD, Cronin SJF, Walz R, Andrews NA, Latini A (2021) Impaired dopamine metabolism is linked to fatigability in mice and fatigue in Parkinson's disease patients. Brain Commun 3:fcab116. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Skeletal muscle |
| Went 2021 MitoFit PB | 2021 | Went N, Di Marcello M, Gnaiger E (2021) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by High-Resolution PhotoRespirometry. https://doi.org/10.26124/mitofit:2021-0005 | ROUTINE | Intact cells | Algae | ||
| Ayer 2021 Redox Biol | 2021 | Ayer A, Fazakerley DJ, Suarna C, Maghzal GJ, Sheipouri D, Lee KJ, Bradley MC, Fernández-Del-Rio L, Tumanov S, Kong SM, van der Veen JN, Yang A, Ho JWK, Clarke SG, James DE, Dawes IW, Vance DE, Clarke CF, Jacobs RL, Stocker R (2021) Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q. Redox Biol 46:102127. | ROUTINE ET | Intact organism | Saccharomyces cerevisiae | ||
| Chang 2021 J Fungi (Basel) | 2021 | Chang CK, Kao MC, Lan CY (2021) Antimicrobial activity of the peptide LfcinB15 against Candida albicans. J Fungi (Basel) 7:519. | ET ROUTINE | Intact cells | Fungi | ||
| Styles 2021 Cell Death Dis | 2021 | Styles FL, Al-Owais MM, Scragg JL, Chuntharpursat-Bon E, Hettiarachchi NT, Lippiat JD, Minard A, Bon RS, Porter K, Sukumar P, Peers C, Roberts LD (2021) Kv1.3 voltage-gated potassium channels link cellular respiration to proliferation through a non-conducting mechanism. Cell Death Dis 12:372. | LEAK ROUTINE ET | CIV ROX | Intact cells | Human | HEK |
| Hoppel 2021 Front Physiol | 2021 | Hoppel F, Calabria E, Pesta DH, Kantner-Rumplmair W, Gnaiger E, Burtscher M (2021) Effects of ultramarathon running on mitochondrial function of platelets and oxidative stress parameters: a pilot study. https://doi.org/10.3389/fphys.2021.632664 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet |
| Vernerova 2021 Biomedicines | 2021 | Vernerova A, Garcia-Souza LF, Soucek O, Kostal M, Rehacek V, Krcmova LK, Gnaiger E, Sobotka O (2021) Mitochondrial respiration of platelets: comparison of isolation methods. https://doi.org/10.3390/biomedicines9121859 | LEAK ROUTINE ET | ROX | Intact cells | Human | Platelet |
| Iadarola 2021 J Biol Chem | 2021 | Iadarola DM, Joshi A, Caldwell CB, Gohil VM (2021) Choline restores respiration in Psd1-deficient yeast by replenishing mitochondrial phosphatidylethanolamine. J Biol Chem 296:100539. | ET ROUTINE | ROX | Intact cells Intact organism | Saccharomyces cerevisiae | |
| Went 2021 Batchelor thesis | 2021 | Went N (2021) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by High-Resolution PhotoRespirometry. Batchelor thesis:26 pp. | ROUTINE | Plants | |||
| Hesse 2021 FASEB J | 2021 | Hesse J, Groterath W, Owenier C, Steinhausen J, Ding Z, Steckel B, Czekelius C, Alter C, Marzoq A, Schrader J (2021) Normoxic induction of HIF-1α by adenosine-A2B R signaling in epicardial stromal cells formed after myocardial infarction. FASEB J 35:21517. | ROUTINE | Intact cells | Rat | Heart Fibroblast | |
| Brodnanova 2021 Eur J Pharmacol | 2021 | Brodnanova M, Hatokova Z, Evinova A, Cibulka M, Racay P (2021) Differential impact of imipramine on thapsigargin- and tunicamycin-induced endoplasmic reticulum stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells. Eur J Pharmacol 902:174073. | LEAK ROUTINE ET | N S ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
| Gvozdjakova 2021 PLoS One | 2021 | Gvozdjáková A, Sumbalová Z, Kucharská J, Szamosová M, Čápová L, Rausová Z, Vančová O, Mojto V, Langsjoen P, Palacka P (2021) Platelet mitochondrial respiration and coenzyme Q10 could be used as new diagnostic strategy for mitochondrial dysfunction in rheumatoid diseases. PLoS ONE 16:e0256135. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet |
| Wu 2021 Am J Physiol Cell Physiol | 2021 | Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, Parslow D, Armistead S, Lemire K, Orrell J, Teich J, Chomicz S, Ferrick DA (2021) Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. Am J Physiol Cell Physiol 292:C125-36. doi: 10.1152/ajpcell.00247.2006 | ROUTINE ET | Intact cells | Human | Other cell lines | |
| Kripnerova 2021 J Clin Med | 2021 | Kripnerová M, Parmar HS, Šána J, Kopková A, Radová L, Sopper S, Biernacki K, Jedlička J, Kohoutová M, Kuncová J, Peychl J, Rudolf E, Červinka M, Houdek Z, Dvořák P, Houfková K, Pešta M, Tůma Z, Dolejšová M, Tichánek F, Babuška V, Leba M, Slabý O, Hatina J (2021) Complex interplay of genes underlies invasiveness in fibrosarcoma progression model. J Clin Med 10:2297. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fibroblast |
| Weiss 2021 Crit Care Explor | 2021 | Weiss SL, Bittinger K, Lee JJ, Friedman ES, Mattei LM, Graham K, Zhang D, Bush J, Balamuth F, McGowan FX Jr, Bushman FD, Baldassano RN, Wu GD, Wallace DC, Collman RG (2021) Decreased intestinal microbiome diversity in pediatric sepsis: a conceptual framework for intestinal dysbiosis to influence immunometabolic function. Crit Care Explor 3:0360. | LEAK ROUTINE ET | ROX | Intact cells | Human | Lymphocyte |
| Zhang 2021 Pharmaceutics | 2021 | Zhang H, Zhang A, Gupte AA, Hamilton DJ (2021) Plumbagin elicits cell-specific cytotoxic effects and metabolic responses in melanoma cells. Pharmaceutics 13:706. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
| Liang 2021 Biomed Pharmacother | 2021 | Liang L, Zhang G, Cheng C, Li H, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W (2021) High-resolution respirometry for evaluation of mitochondrial function on brain and heart homogenates in a rat model of cardiac arrest and cardiopulmonary resuscitation. Biomed Pharmacother 142:111935. | LEAK OXPHOS ROUTINE | N S CIV ROX | Homogenate | Rat | Heart Nervous system |
| Giordano 2021 Gene Ther | 2021 | Giordano L, Aneja MK, Sommer N, Alebrahimdehkordi N, Seraji A, Weissmann N, Rudolph C, Plank C, Jacobs HT, Szibor M (2021) Alternative oxidase encoded by sequence-optimized and chemically-modified RNA transfected into mammalian cells is catalytically active. https://doi.org/10.1038/s41434-021-00235-z | LEAK ROUTINE OXPHOS | N S CIV ROX | Permeabilized cells Intact cells | Mouse | Fibroblast |
| Riguet 2021 Nat Commun | 2021 | Riguet N, Mahul-Mellier AL, Maharjan N, Burtscher J, Croisier M, Knott G, Hastings J, Patin A, Reiterer V, Farhan H, Nasarov S, Lashuel HA (2021) Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties. Nat Commun 12:6579. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | HEK |
| Ko 2021 Biomolecules | 2021 | Ko HJ, Tsai CY, Chiou SJ, Lai YL, Wang CH, Cheng JT, Chuang TH, Huang CF, Kwan AL, Loh JK, Hong YR (2021) The phosphorylation status of Drp1-Ser637 by PKA in mitochondrial fission modulates mitophagy via PINK1/Parkin to exert multipolar spindles assembly during mitosis. Biomolecules 11:424. | LEAK ROUTINE ET | ROX | Intact cells | Human | HeLa |
| Klepinina 2021 PLoS One | 2021 | Klepinina L, Klepinin A, Truu L, Chekulayev V, Vija H, Kuus K, Teino I, Pook M, Maimets T, Kaambre T (2021) Colon cancer cell differentiation by sodium butyrate modulates metabolic plasticity of Caco-2 cells via alteration of phosphotransfer network. PLoS One 16:e0245348. | LEAK ROUTINE OXPHOS ET | N NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Beaufils 2021 J Allergy Clin Immunol | 2021 | Beaufils F, Esteves P, Enaud R, Germande O, Celle A, Marthan R, Trian T, Fayon M, Berger P (2021) Mitochondria are involved in bronchial smooth muscle remodeling in severe preschool wheezers. J Allergy Clin Immunol 148:645-51. | ROUTINE | Intact cells | Human | Lung;gill | |
| Alves 2021 Eur J Nutr | 2021 | Alves BL, Araújo TDR, Guimarães DSPSF, Zoppi CC, Figueiredo MS, Carneiro EM (2021) Amino acid restriction alters survival mechanisms in pancreatic beta cells: possible role of the PI3K/Akt pathway. Eur J Nutr 60:3947-57. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Islet cell;pancreas;thymus |
| Saura-Esteller 2021 Int J Mol Sci | 2021 | Saura-Esteller J, Sánchez-Vera I, Núñez-Vázquez S, Cosialls AM, Gama-Pérez P, Bhosale G, Mendive-Tapia L, Lavilla R, Pons G, Garcia-Roves PM, Duchen MR, Iglesias-Serret D, Gil J (2021) Activation of the integrated stress response and ER stress protect from fluorizoline-induced apoptosis in HEK293T and U2OS cell lines. Int J Mol Sci 22:6117. | LEAK ROUTINE ET | ROX | Intact cells | Human | Lymphocyte HEK |
| Herraez 2021 Pharmaceutics | 2021 | Herraez R, Quesada R, Dahdah N, Vinas M, Vinuesa T (2021) Tambjamines and prodiginines: Biocidal activity against Trypanosoma cruzi. Pharmaceutics 13:705. | ROUTINE | ROX | Intact cells | Protists | |
| Bastos Sant'Anna Silva 2021 Cancers (Basel) | 2021 | Bastos Sant'Anna Silva AC, Perez Valencia JA, Sciacovelli M, Lalou C, Sarlak S, Tronci L, Nikitopoulou E, Meszaros AT, Frezza C, Rossignol R, Gnaiger E, Klocker H (2021) Succinate anaplerosis has an onco-driving potential in prostate cancer cells. https://doi.org/10.3390/cancers13071727 | LEAK ROUTINE OXPHOS | S ROX | Permeabilized cells Intact cells | Human | Genital |
| Jasz 2021 J Cell Mol Med | 2021 | Jász DK, Szilágyi ÁL, Tuboly E, Baráth B, Márton AR, Varga P, Varga G, Érces D, Mohácsi Á, Szabó A, Bozó R, Gömöri K, Görbe A, Boros M, Hartmann P (2021) Reduction in hypoxia-reoxygenation-induced myocardial mitochondrial damage with exogenous methane. https://doi.org/10.1111/jcmm.16498 | LEAK ROUTINE OXPHOS ET | S ROX | Permeabilized cells Isolated mitochondria | Rat | Heart |
| Theall 2021 Physiol Rep | 2021 | Theall B, Stampley J, Cho E, Granger J, Johannsen NM, Irving BA, Spielmann G (2021) Impact of acute exercise on peripheral blood mononuclear cells nutrient sensing and mitochondrial oxidative capacity in healthy young adults. Physiol Rep 9:e15147. | LEAK ROUTINE OXPHOS ET | N NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Gerna 2021 Int J Mol Sci | 2021 | Gerna D, Arc E, Holzknecht M, Roach T, Jansen-Duerr P, Weiss AKH, Kranner I (2021) AtFAHD1a: a new player influencing seed longevity and dormancy in arabidopsis?. Int J Mol Sci 22:2997. | ROUTINE | CIV | Intact organ | Plants | |
| Amoedo 2021 J Clin Invest | 2021 | Amoedo ND, Sarlak S, Obre E, Esteves P, Bégueret H, Kieffer Y, Rousseau B, Dupis A, Izotte J, Bellance N, Dard L, Redonnet-Vernhet I, Punzi G, Rodrigues MF, Dumon E, Mafhouf W, Guyonnet-Dupérat V, Gales L, Palama T, Bellvert F, Dugot-Senan N, Claverol S, Baste JM, Lacombe D, Rezvani HR, Pierri CL, Mechta-Grigoriou F, Thumerel M, Rossignol R (2021) Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas. J Clin Invest 131:e133081. | LEAK ROUTINE | F CIV | Intact cells | Human | Lung;gill |
| Young 2021 J Biol Chem | 2021 | Young MP, Schug ZT, Booth DM, Yule DI, Mikoshiba K, Hajnóczky G, Joseph SK (2021) Metabolic adaptation to the chronic loss of Ca2+ signaling induced by knockout of IP 3 receptors or the mitochondrial Ca2+ uniporter. J Biol Chem 298:101436. | LEAK ROUTINE ET | ROX | Intact cells | Human | HEK HeLa |
| Sighel 2021 Cell Rep | 2021 | Sighel D, Notarangelo M, Aibara S, Re A, Ricci G, Guida M, Soldano A, Adami V, Ambrosini C, Broso F, Rosatti EF, Longhi S, Buccarelli M, D'Alessandris QG, Giannetti S, Pacioni S, Ricci-Vitiani L, Rorbach J, Pallini R, Roulland S, Amunts A, Mancini I, Modelska A, Quattrone A (2021) Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Rep 35:109024. | ROUTINE OXPHOS | N S NS ROX | Permeabilized cells Intact cells | Human | Nervous system Stem cells |
| Avram 2021 Life (Basel) | 2021 | Avram VF, Bina AM, Sima A, Aburel OM, Sturza A, Burlacu O, Timar RZ, Muntean DM, Elmer E, Cretu OM (2021) Improvement of platelet respiration by cell-permeable succinate in diabetic patients treated with statins. Life (Basel) 11:288. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet |
| Conceicao 2021 Sci Rep | 2021 | Conceição CC, da Silva JN, Arcanjo A, Nogueira CL, de Abreu LA, de Oliveira PL, Gondim KC, Moraes B, de Carvalho SS, da Silva RM, da Silva Vaz I Jr, Moreira LA, Logullo C (2021) Aedes fluviatilis cell lines as new tools to study metabolic and immune interactions in mosquito-Wolbachia symbiosis. Sci Rep 11:19202. | LEAK ROUTINE ET | ROX | Intact cells | Molluscs | |
| Sanchez-de-Diego 2021 Redox Biol | 2021 | Sánchez-de-Diego C, Pedrazza L, Pimenta-Lopes C, Martinez-Martinez A, Dahdah N, Valer JA, Garcia-Roves P, Rosa JL, Ventura F (2021) NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression. Redox Biol 40:101845. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Other cell lines |
| Kladnicka 2021 Biomolecules | 2021 | Kladnicka I, Cedikova M, Jedlicka J, Kohoutova M, Muller L, Plavinova I, Kripnerova M, Bludovska M, Kuncova J, Mullerova D (2021) Chronic DDE exposure modifies mitochondrial respiration during differentiation of human adipose-derived mesenchymal stem cells into mature adipocytes. Biomolecules 11:1068. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fat |
| Komlodi 2021 BEC AmR-O2 | 2021 | Komlódi T, Sobotka O, Gnaiger E (2021) Facts and artefacts on the oxygen dependence of hydrogen peroxide production using Amplex UltraRed. https://doi.org/10.26124/bec:2021-0004 | ROUTINE | Intact cells | Saccharomyces cerevisiae | Other cell lines | |
| Schumann 2021 Commun Biol | 2021 | Schumann T, Koenig J, von Loeffelholz C, Vatner DF, Zhang D, Perry RJ, Bernier M, Chami J, Henke C, Kurzbach A, El-Agroudy NN, Willmes DM, Pesta D, de Cabo R, O Sullivan JF, Simon E, Shulman GI, Hamilton BS, Birkenfeld AL (2021) Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance. Commun Biol 4:826. | LEAK ROUTINE OXPHOS ET | F N NS ROX | Intact cells | Mouse | Liver |
| Zhang 2021 PLOS ONE | 2021 | Zhang X, Yuan T, Keijer J, de Boer VCJ (2021) OCRbayes: a Bayesian hierarchical modeling framework for Seahorse extracellular flux oxygen consumption rate data analysis. PLOS ONE 16:e0253926. | LEAK ROUTINE ET | ROX | Fibroblast | ||
| Oemer 2021 J Lipid Res | 2021 | Oemer G, Edenhofer ML, Wohlfarter Y, Lackner K, Leman G, Koch J, Cardoso LHD, Lindner HH, Gnaiger E, Dubrac S, Zschocke J, Keller MA (2021) Fatty acyl availability modulates cardiolipin composition and alters mitochondrial function in HeLa cells. https://doi.org/10.1016/j.jlr.2021.100111 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells | Human | HeLa |
| Flouda 2021 Free Radic Biol Med | 2021 | Flouda K, Mercer J, Davies MJ, Hawkins CL (2021) Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage. Free Radic Biol Med 166:165-77. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
| Assis-de-Lemos 2021 Biosci Rep | 2021 | Assis-de-Lemos G, Monteiro J, Oliveira-Valença VM, Melo GA, Reis RAM, Rehen SK, Silveira MS, Galina A (2021) Dopamine signaling impairs ROS modulation by mitochondrial hexokinase in human neural progenitor cells. https://doi.org/10.1042/bsr20211191 | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
| Fu 2021 Biochem Biophys Rep | 2021 | Fu X, Chen S, Wang X, Shen Y, Zeng R, Wu Q, Lu Y, Shi J, Zhou S (2021) Dendrobium nobile Lindl. alkaloids alleviate Mn-induced neurotoxicity via PINK1/Parkin-mediated mitophagy in PC12 cells. Biochem Biophys Rep 26:100877. | ROUTINE | Intact cells | Rat | Nervous system | |
| Cretin 2021 EMBO Mol Med | 2021 | Cretin E, Lopes P, Vimont E, Tatsuta T, Langer T, Gazi A, Sachse M, Yu-Wai-Man P, Reynier P, Wai T (2021) High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts. EMBO Mol Med 13:13579. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fibroblast |
| Avram 2021 Int J Mol Sci | 2021 | Avram VF, Chamkha I, Åsander-Frostner E, Ehinger JK, Timar RZ, Hansson MJ, Muntean DM, Elmér E (2021) Cell-permeable succinate rescues mitochondrial respiration in cellular models of statin toxicity. Int J Mol Sci 22:424. | ROUTINE ET LEAK | ROX | Intact cells | Human | Platelet |
| Siewiera 2021 Int J Mol Sci | 2021 | Siewiera K, Labieniec-Watala M, Wolska N, Kassassir H, Watala C (2021) Sample preparation as a critical aspect of blood platelet mitochondrial respiration measurements - The impact of platelet activation on mitochondrial respiration. https://doi.org/10.3390/ijms22179332 | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Axelrod 2021 EMBO Mol Med | 2021 | Axelrod CL, King WT, Davuluri G, Noland RC, Hall J, Hull M, Dantas WS, Zunica ER, Alexopoulos SJ, Hoehn KL, Langohr I, Stadler K, Doyle H, Schmidt E, Nieuwoudt S, Fitzgerald K, Pergola K, Fujioka H, Mey JT, Fealy C, Mulya A, Beyl R, Hoppel CL, Kirwan JP (2021) BAM15-mediated mitochondrial uncoupling protects against obesity and improves glycemic control. EMBO Mol Med 12:12088. | ROUTINE OXPHOS ET LEAK | F N S NS ROX DQ | Intact cells Permeabilized tissue | Mouse | Skeletal muscle |
| MiPNet21.17 BloodCellsIsolation | 2020-10-22 |  | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Intact cells Permeabilized cells | Human | Blood cells Platelet |
| Maeda 2020 J Cell Mol Med | 2020 | Maeda H, Kami D, Maeda R, Murata Y, Jo JI, Kitani T, Tabata Y, Matoba S, Gojo S (2020) TAT-dextran-mediated mitochondrial transfer enhances recovery from models of reperfusion injury in cultured cardiomyocytes. J Cell Mol Med 24:5007-20. | LEAK ROUTINE OXPHOS ET | N ROX | Isolated mitochondria Intact cells | Rat | Heart |
| Dia 2020 Basic Res Cardiol | 2020 | Dia M, Gomez L, Thibault H, Tessier N, Leon C, Chouabe C, Ducreux S, Gallo-Bona N, Tubbs E, Bendridi N, Chanon S, Leray A, Belmudes L, Couté Y, Kurdi M, Ovize M, Rieusset J, Paillard M (2020) Reduced reticulum-mitochondria Caysup>2+ transfer is an early and reversible trigger of mitochondrial dysfunctions in diabetic cardiomyopathy. Basic Res Cardiol 115:74. | ROUTINE ET | Intact cells | Mouse | Heart | |
| Ayari 2020 Commun Biol | 2020 | Ayari Asma, Rosa-Calatrava Manuel, Lancel Steve, Barthelemy Johanna, Pizzorno Andres, Mayeuf-Louchart Alicia, Baron Morgane, Hot David, Deruyter Lucie, Soulard Daphnee, Julien Thomas, Faveeuw Christelle, Molendi-Coste Olivier, Dombrowicz David, Sedano Laura, Sencio Valentin, Le Goffic Ronan, Trottein Francois, Wolowczuk Isabelle (2020) Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues. Commun Biol 3:237. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fat |
| Leguina-Ruzzi 2020 Biomolecules | 2020 | Leguina-Ruzzi A, Vodičková A, Holendová B, Pavluch V, Tauber J, Engstová H, Dlasková A, Ježek P (2020) Glucose-induced expression of DAPIT in pancreatic β-cells. Biomolecules 10:E1026. | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
| Shi 2020 Diabetes | 2020 | Shi JH, Lu JY, Chen HY, Wei CC, Xu X, Li H, Bai Q, Xia FZ, Lam SM, Zhang H, Shi YN, Cao D, Chen L, Shui G, Yang X, Lu Y, Chen YX, Zhang WJ (2020) Liver ChREBP protects against fructose-induced glycogenic hepatotoxicity by regulating L-type pyruvate kinase. Diabetes 120:29. | LEAK ROUTINE ET | Intact cells | Mouse | Liver | |
| Seitaj 2020 Cells | 2020 | Seitaj B, Maull F, Zhang L, Wüllner V, Wolf C, Schippers P, La Rovere R, Distler U, Tenzer S, Parys JB, Bultynck G, Methner A (2020) Transmembrane BAX inhibitor-1 motif containing protein 5 (TMBIM5) sustains mitochondrial structure, shape, and function by impacting the mitochondrial protein synthesis machinery. Cells 9:E2147. | LEAK ROUTINE ET | ROX | Intact cells | Human | Kidney |
| Contreras Mostazo 2020 Cancers (Basel) | 2020 | Mostazo MGC, Kurrle N, Casado M, Fuhrmann D, Alshamleh I, Häupl B, Martín-Sanz P, Brüne B, Serve H, Schwalbe H, Schnütgen F, Marin S, Cascante M (2020) Metabolic plasticity is an essential requirement of acquired tyrosine kinase inhibitor resistance in chronic myeloid leukemia. Cancers (Basel) 12:E3443. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Franco 2020 bioRxiv | 2020 | Franco JLM, Genoula M, Corral D, Duette G, Ferreyra M, Maio M, Dolotowicz MB, Aparicio-Trejo OE, Patiño-Martínez E, Fuentes F, Soldan V, Moraña EJ, Palmero D, Ostrowski M, Schierloh P, Sánchez-Torres C, Hernández-Pando R, Pedraza-Chaverri J, Rombouts Y, Layre E, Hudrisier D, Vérollet C, Neyrolles O, Sasiain MC, Lugo-Villarino G, Balboa L (2020) Host-derived lipids from tuberculous pleurisy impair macrophage microbicidal-associated metabolic activity. bioRxiv doi: https://doi.org/10.1101/2020.03.23.001818 . | LEAK ROUTINE | N S CIV ROX | Intact cells | Human | Macrophage-derived |
| Mahul-Mellier 2020 Proc Natl Acad Sci U S A | 2020 | Mahul-Mellier AL, Burtscher J, Maharjan N, Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW, Lashuel HA (2020) The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proc Natl Acad Sci U S A 117:4971-82. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Mouse | Nervous system |
| Nolfi-Donegan 2020 Redox Biol | 2020 | Nolfi-Donegan D, Braganza A, Shiva S (2020) Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement. Redox Biol 37:101674. https://doi.org/10.1016/j.redox.2020.101674 | LEAK ROUTINE ET | ||||
| Dawid 2020 Biochim Biophys Acta Bioenerg | 2020 | Dawid C, Weber D, Musiol E, Janas V, Baur S, Lang R, Fromme T (2020) Comparative assessment of purified saponins as permeabilization agents during respirometry. Biochim Biophys Acta Bioenerg 1861:148251. | LEAK ROUTINE OXPHOS ET | N S Gp NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human Mouse | Nervous system HEK |
| Ledur 2020 Sci Rep | 2020 | Ledur PF, Karmirian K, Pedrosa CDSG, Souza LRQ, Assis-de-Lemos G, Martins TM, Ferreira JCCG, de Azevedo Reis GF, Silva ES, Silva D, Salerno JA, Ornelas IM, Devalle S, Madeiro da Costa RF, Goto-Silva L, Higa LM, Melo A, Tanuri A, Chimelli L, Murata MM, Garcez PP, Filippi-Chiela EC, Galina A, Borges HL, Rehen SK (2020) Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes. Sci Rep 10:1218. | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
| Almoiliqy 2020 Acta Pharmacol Sin | 2020 | Almoiliqy M, Wen J, Xu B, Sun YC, Lian MQ, Li YL, Qaed E, Al-Azab M, Chen DP, Shopit A, Wang L, Sun PY, Lin Y (2020) Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53. Acta Pharmacol Sin 41:1208-22. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Rat | Endothelial;epithelial;mesothelial cell |
| Boehmert 2020 Transfusion | 2020 | Böhmert S, Kübel S, Müller MM, Weber CF, Adam EH, Dröse S, Zacharowski K, Fischer D (2020) The effect of the interruption of agitation, temporary cooling, and pneumatic tube transportation on platelet quality during storage for transfusion. Transfusion 61:1258-65. | LEAK ROUTINE ET | CIV | Intact cells | Human | Platelet |
| Smolkova 2020 Sci Rep | 2020 | Smolková K, Špačková J, Gotvaldová K, Dvořák A, Křenková A, Hubálek M, Holendová B, Vítek L, Ježek P (2020) SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2 . Sci Rep 10:8677. | ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines | |
| Bianchi 2020 IUBMB Life | 2020 | Bianchi SE, Pegues MA, Dias CK, Mascia F, Doneda E, Pittol V, Rao A, Klamt F, Bassani VL (2020) Achyrocline satureioides compounds, achyrobichalcone and 3-O-methylquercetin, induce mitochondrial dysfunction and apoptosis in human breast cancer cell lines. IUBMB Life 72:2133-45. | ROUTINE | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Dawson 2020 Exp Gerontol | 2020 | Dawson NJ, Salmón P (2020) Age-related increase in mitochondrial quantity may mitigate a decline in mitochondrial quality in red blood cells from zebra finches (Taeniopygia guttata). Exp Gerontol 133:110883. | LEAK ROUTINE ET | ROX | Intact cells | Birds | Blood cells |
| Dymkowska 2020 J Appl Toxicol | 2020 | Dymkowska D, Wrzosek A, Zabłocki K (2020) Atorvastatin and pravastatin stimulate nitric oxide and reactive oxygen species generation, affect mitochondrial network architecture and elevate nicotinamide N-methyltransferase level in endothelial cells. J Appl Toxicol 41:1076-88. | LEAK ET ROUTINE | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
| Gvozdjakova 2020 Diagnostics (Basel) | 2020 | Gvozdjáková A, Sumbalová Z, Kucharská J, Komlósi M, Rausová Z, Vančová O, Számošová M, Mojto V (2020) Platelet mitochondrial respiration, endogenous coenzyme Q10 and oxidative stress in patients with chronic kidney disease. Diagnostics (Basel) 10:176. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet |
| Reddoch-Cardenas 2020 Transfusion | 2020 | Reddoch-Cardenas KM, Peltier GC, Chance TC, Nair PM, Meledeo MA, Ramasubramanian AK, Cap AP, Bynum JA (2020) Cold storage of platelets in platelet additive solution maintains mitochondrial integrity by limiting initiation of apoptosis-mediated pathways. Transfusion 61:178-90. | ROUTINE ET | Intact cells | Human | Platelet | |
| Owiredu 2020 Am J Physiol Cell Physiol | 2020 | Owiredu S, Ranganathan A, Eckmann DM, Shofer FS, Hardy K, Lambert DS, Kelly M, Jang DH (2020) Ex vivo use of cell-permeable succinate prodrug attenuates mitochondrial dysfunction in blood cells obtained from carbon monoxide poisoned individuals. Am J Physiol Cell Physiol 319:C129-35. | LEAK ROUTINE ET | S CIV ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Close 2020 Cells | 2020 | Close AF, Dadheech N, Lemieux H, Wang Q, Buteau J (2020) Disruption of beta-cell mitochondrial networks by the orphan nuclear receptor Nor1/Nr4a3. Cells 9:E168. | LEAK ROUTINE | N S CIV NS ROX | Permeabilized cells Intact cells | Rat | Islet cell;pancreas;thymus |
| Chen 2020 Chem Biol Interact | 2020 | Chen HY, Ho YJ, Chou HC, Liao EC, Tsai YT, Wei YS, Lin LH, Lin MW, Wang YS, Ko ML, Chan H (2020) TGF-β1 signaling protects retinal ganglion cells from oxidative stress via modulation of the HO-1/Nrf2 pathway. Chem Biol Interact 331:109249. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Nervous system |
| Kunz 2020 J Biol Chem | 2020 | Kunz HE, Dorschner JM, Berent TE, Meyer T, Wang X, Jatoi A, Kumar R, Lanza IR (2020) Methylarginine metabolites are associated with attenuated muscle protein synthesis in cancer-associated muscle wasting. J Biol Chem 295:17441-59. | LEAK ROUTINE OXPHOS ET | N NS ROX S | Permeabilized tissue Intact cells | Mouse | Skeletal muscle |
| Peres de Oliveira 2020 Proteome Sci | 2020 | Peres de Oliveira A, Basei FL, Slepicka PF, de Castro Ferezin C, Melo-Hanchuk TD, de Souza EE, Lima TI, Dos Santos VT, Mendes D, Silveira LR, Menck CFM, Kobarg J (2020) NEK10 interactome and depletion reveal new roles in mitochondria. Proteome Sci 18:4. | LEAK ROUTINE ET | Intact cells | Human | HeLa | |
| Gutierrez 2020 Sci Signal | 2020 | Gutiérrez T, Qi H, Yap MC, Tahbaz N, Milburn LA, Lucchinetti E, Lou PH, Zaugg M, LaPointe PG, Mercier P, Overduin M, Bischof H, Burgstaller S, Malli R, Ballanyi K, Shuai J, Simmen T (2020) The ER chaperone calnexin controls mitochondrial positioning and respiration . Sci Signal 13:eaax6660. | LEAK ROUTINE ET | Intact cells | Mouse | Fibroblast | |
| MitoEAGLE blood cells 1 | 2020 | Åsander Frostner Eleonor*, Aburel Oana M*, Avram Vlad F*, Calabria Elisa, Castelo Rueda Maria Paulina*, Chamkha Imen*, Čižmárová Beata, Danila Maria-Daniela*, Doerrier Carolina*, Eckert Gunter P*, Ehinger Johannes K, Elmer Eskil*, Garcia-Souza Luiz F*, Gnaiger Erich*, Hoppel Florian*, Karabatsiakis Alexander*, Keppner Gloria, Kidere Dita*, Krako Jakovljević Nina, Labieniec-Watala Magdalena*, Lelcu Theia*, Micankova Petra, Michalak Slawomir*, Molina Anthony JA*, Pavlovic Kasja, Pichler Irene*, Piel Sarah, Rousar Tomas, Rybacka-Mossakowska Joanna, Schartner Melanie, Siewiera Karolina*, Silaidos Carmina*, Sjövall Fredrik*, Sobotka Ondrej*, Sumbalova Zuzana*, Swiniuch Daria, Vernerova Andrea*, Volani Chiara*, Vujacic-Mirski Ksenija*, Watala Cezary* (2020) Interlaboratory guide to mitochondrial respiratory studies with peripheral blood mononuclear cells and platelets. - Updated: 2020-03-06 - *Confirmed | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Intact cells Permeabilized cells | Human | Blood cells Platelet |
| Lin 2020 EBioMedicine | 2020 | Lin Y, Nan J, Shen J, Lv X, Chen X, Lu X, Zhang C, Xiang P, Wang Z, Li Z (2020) Canagliflozin impairs blood reperfusion of ischaemic lower limb partially by inhibiting the retention and paracrine function of bone marrow derived mesenchymal stem cells. EBioMedicine 52:102637. | ROUTINE ET | Intact cells | Mouse | Stem cells | |
| Assis-de-Lemos 2020 Curr Protoc Toxicol | 2020 | Assis-de-Lemos G, Ledur PF, Karmirian K, Rehen SK, Galina A (2020) A protocol to study mitochondrial function in human neural progenitors and iPSC-derived astrocytes. Curr Protoc Toxicol 85:e97. | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
| Risiglione 2020 Int J Mol Sci | 2020 | Risiglione P, Leggio L, Cubisino SAM, Reina S, Paternò G, Marchetti B, Magrì A, Iraci N, Messina A (2020) High-resolution respirometry reveals MPP+ mitochondrial toxicity mechanism in a cellular model of parkinson's disease. Int J Mol Sci 21:E7809. https://doi.org/10.3390/ijms21217809 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
| Juarez-Flores 2020 Antioxidants (Basel) | 2020 | Juarez-Flores DL, Ezquerra M, Gonzalez-Casacuberta I, Ormazabal A, Moren C, Tolosa E, Fucho R, Guitart-Mampel M, Casado M, Valldeoriola F, de la Torre-Lara J, Munoz E, Tobias E, Compta Y, Garcia-Garcia FJ, Garcia-Ruiz C, Fernandez-Checa JC, Marti MJ, Grau JM, Cardellach F, Artuch R, Fernandez-Santiago R, Garrabou G (2020) Disrupted mitochondrial and metabolic plasticity underlie comorbidity between age-related and degenerative disorders as Parkinson disease and type 2 diabetes mellitus. Antioxidants (Basel) 9:1063. | LEAK ROUTINE ET | ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Keppner 2020 Thesis | 2020 | Keppner G (2020) Impact of gut microbiota composition, liver metabolism and respiratory capacity of peripheral blood mononuclear cells on resting metabolic rate. PhD Thesis 100. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Evinova 2020 J Membr Biol | 2020 | Evinova A, Cizmarova B, Hatokova Z, Racay P (2020) High‑resolution respirometry in assessment of mitochondrial function in neuroblastoma SH‑SY5Y intact cells. J Membr Biol 253:129-36. | LEAK ROUTINE ET | N S ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
| Lin 2020 Preprints | 2020 | Lin M, Fu T, Hsu C, Huang S, Lin Y, Wang J (2020) Cycling exercise training enhances mitochondrial bioenergetics of platelets in patients with peripheral arterial disease: a randomized controlled trial. Preprints 2020070567. | LEAK ROUTINE OXPHOS ET | F N S Gp NS ROX | Permeabilized cells Intact cells | Human | Platelet |
| Burgin 2020 Int J Mol Sci | 2020 | Burgin HJ, Lopez Sanchez MIG, Smith CM, Trounce IA, McKenzie M (2020) Pioglitazone and deoxyribonucleoside combination treatment increases mitochondrial respiratory capacity in m.3243A>G MELAS cybrid cells. Int J Mol Sci 21:E2139. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
| Cipullo 2020 Nucleic Acids Res | 2020 | Cipullo M, Pearce SF, Lopez Sanchez IG, Gopalakrishna S, Krüger A, Schober F, Busch JD, Li X, Wredenberg A, Atanassov I, Rorbach J (2020) Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly. Nucleic Acids Res 49:354-70. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | HEK |
| Plecita-Hlavata 2020 Antioxid Redox Signal | 2020 | Plecitá-Hlavatá L, Engstová H, Holendová B, Tauber J, Špaček T, Petrásková L, Křen V, Špačková J, Gotvaldová K, Ježek J, Dlasková A, Smolková K, Ježek P (2020) Mitochondrial superoxide production decreases on glucose-stimulated insulin secretion in pancreatic β cells due to decreasing mitochondrial matrix NADH/NAD+ ratio. Antioxid Redox Signal 33:789-815. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Islet cell;pancreas;thymus |
| Beninca 2020 J Med Genet | 2020 | Beninca C, Zanette V, Brischigliaro M, Johnson M, Reyes A, Valle DAD, Robinson AJ, Degiorgi A, Yeates A, Telles BA, Prudent J, Baruffini E, Santos ML, de Souza RL, Fernandez-Vizarra E, Whitworth A, Zeviani M (2020) Mutation in the MICOS subunit gene APOO (MIC26) associated with an X-linked recessive mitochondrial myopathy, lactic acidosis, cognitive impairment and autistic features. J Med Genet 58:155-67. | LEAK ROUTINE ET | Intact cells | Human | Fibroblast | |
| Protasoni 2020 EMBO J | 2020 | Protasoni M, Pérez-Pérez R, Lobo-Jarne T, Harbour ME, Ding S, Peñas A, Diaz F, Moraes CT, Fearnley IM, Zeviani M, Ugalde C, Fernández-Vizarra E (2020) Respiratory supercomplexes act as a platform for complex III-mediated maturation of human mitochondrial complexes I and IV. EMBO J 39:e102817. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
| Macasoi 2020 Oncol Rep | 2020 | Macașoi I, Pavel IZ, Moacă AE, Avram S, David LV, Coricovac D, Mioc A, Spandidos DA, Tsatsakis A, Șoica C, Dumitrașcu V, Dehelean C (2020) Mechanistic investigations of antitumor activity of a Rhodamine B‑oleanolic acid derivative bioconjugate. Oncol Rep 44:1169-83. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Alahmad 2020 EMBO Mol Med | 2020 | Alahmad A, Nasca A, Heidler J, Thompson K, Oláhová M, Legati A, Lamantea E, Meisterknecht J, Spagnolo M, He L, Alameer S, Hakami F, Almehdar A, Ardissone A, Alston CL, McFarland R, Wittig I, Ghezzi D, Taylor RW (2020) Bi-allelic pathogenic variants in NDUFC2 cause early-onset Leigh syndrome and stalled biogenesis of complex I. EMBO Mol Med 12:e12619. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
| Schoepf 2020 Nat Commun | 2020 | Schöpf Bernd, Weissensteiner Hansi, Schäfer Georg, Fazzini Federica, Charoentong Pornpimol, Naschberger Andreas, Rupp Bernhard, Fendt Liane, Bukur Valesca, Giese Irina, Sorn Patrick, Sant’Anna-Silva Ana Carolina, Iglesias-Gonzalez Javier, Sahin Ugur, Kronenberg Florian, Gnaiger Erich, Klocker Helmut (2020) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. https://doi.org/10.1038/s41467-020-15237-5 | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Permeabilized tissue | Human | Genital Other cell lines |
| Huete-Ortega 2020 MitoFit Preprint Arch EA | 2020 | Huete-Ortega M, Di Marcello M, Iglesias-Gonzalez J, Gnaiger E (2020) High-resolution respirometry for chloroplast and mitochondrial bioenergetics in Chlamydomonas reinhardtii ― towards biotechnology exploitations. https://doi.org/10.26124/mitofit:ea20.algaeurope.0001 | ROUTINE | Other combinations | Intact cells | Algae | |
| De Souza 2020 Heliyon | 2020 | De Souza CEA, Andrade Pires AR, Cardoso CR, Carlos RM, Cadena SMSC, Acco A (2020) Antineoplastic activity of a novel ruthenium complex against human hepatocellular carcinoma (HepG2) and human cervical adenocarcinoma (HeLa) cells. Heliyon 6:e03862. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver HeLa |
| Oliveira 2020 Anim Reprod | 2020 | Oliveira VS, Castro AJG, Domingues JT, Souza AZP, Scheffer DL, Latini A, Soares CHL, Van Der Kraak G, Silva FRMB (2020) A brazilian pulp and paper mill effluent disrupts energy metabolism in immature rat testis and alters sertoli cell secretion and mitochondrial activity. Anim Reprod 17:e20190116. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Genital |
| Lara-Marqueza 2020 J Funct Foods | 2020 | Lara-Márquez M, Báez-Magaña M, Raymundo-Ramos C, Spagnuolo PA, Macías-Rodríguez L, Salgado-Garciglia R, Ochoa-Zarzosa A, López-Meza JE (2020) Lipid-rich extract from Mexican avocado (Persea americana var. drymifolia) induces apoptosis and modulates the inflammatory response in Caco-2 human colon cancer cells. J Funct Foods 64:103658. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
| Mikulas 2020 Materials | 2020 | Mikulás K, Komlódi T, Földes A, Sváb G, Horváth G, Nagy AM, Ambrus A, Gyulai-Gaál Sz, Gera I, Hermann P, Varga G, Tretter L (2020) Bioenergetic Impairment of triethylene glycol dimethacrylate- (TEGDMA-) treated dental pulp stem cells (DPSCs) and isolated brain mitochondria are amended by redox compound methylene blue. Materials (Basel) 13(16):3472. | OXPHOS ET ROUTINE | N S ROX | Isolated mitochondria Permeabilized cells Intact cells | Guinea pig Human | Stem cells |
| Silaidos 2020 Mitochondrion | 2020 | Silaidos C, Grube J, Muley C, Eckert GP (2020) Time-dependent melatonin secretion is associated with mitochondrial function in peripheral blood mononuclear cells (PBMC) of male volunteers. Mitochondrion 53:21-29. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Dolezelova 2020 PLoS Biol | 2020 | Doleželová E, Kunzová M, Dejung M, Levin M, Panicucci B, Regnault C, Janzen CJ, Barrett MP, Butter F, Zíková A (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei. PLoS Biol 18:e3000741. | LEAK ROUTINE | S Gp CIV | Permeabilized cells Intact cells | Protists | |
| Zhang 2020 Acta Pharmacol Sin | 2020 | Zhang L, Wang YN, Ju JM, Shabanova A, Li Y, Fang RN, Sun JB, Guo YY, Jin TZ, Liu YY, Li TY, Shan HL, Liang HH, Yang BF (2020) Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation. Acta Pharmacol Sin 42:691-700. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Heart |
| Ugarteburu 2020 J Clin Med | 2020 | Ugarteburu O, Sánchez-Vilés M, Ramos J, Barcos-Rodríguez T, Garrabou G, García-Villoria J, Ribes A, Tort F (2020) Physiopathological bases of the disease caused by HACE1 mutations: alterations in autophagy, mitophagy and oxidative stress response. J Clin Med 9:E913. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
| Gnaiger 2020 BEC MitoPathways | 2020 | Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. https://doi.org/10.26124/bec:2020-0002 | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells | Human Mouse | Heart Skeletal muscle Fibroblast |
| Fecker 2020 Biomolecules | 2020 | Fecker R, Buda V, Alexa E, Avram S, Pavel IZ, Muntean D, Cocan I, Watz C, Minda D, Dehelean CA, Soica C, Danciu C (2020) Phytochemical and biological screening of Oenothera biennis L. hydroalcoholic extract. Biomolecules 10:E818. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Wei 2020 Hum Mutat | 2020 | Wei X, Du M, Li D, Wen S, Xie J, Li Y, Chen A, Zhang K, Xu P, Jia M, Wen C, Zhou H, Lyu J, Yang Y, Fang H (2020) Mutations in FASTKD2 are associated with mitochondrial disease with multi-OXPHOS deficiency. Hum Mutat 41:961-72. | LEAK ROUTINE | Intact cells | Human | Lymphocyte | |
| Cruz 2020 Cancers (Basel) | 2020 | Cruz B, Oliveira A, Viana LR, Lopes-Aguiar L, Canevarolo R, Colombera MC, Valentim RR, Garcia-Fóssa F, de Sousa LM, Castelucci BG, Consonni SR, Martins-de-Souza D, de Jesus MB, Russell ST, Gomes-Mardondes MCC (2020) Leucine-tich diet modulates the metabolomic and proteomic profile of skeletal muscle during cancer cachexia. Cancers (Basel) 12:E1880. | LEAK ROUTINE ET | Intact cells | Mouse | Skeletal muscle | |
| Padilla-Flores 2020 Biochem Biophys Res Commun | 2020 | Padilla-Flores T, Lopez-Gonzalez Z, Vaca L, Aparicio-Trejo OE, Briones-Herrera A, Riveros-Rosas H, Pedraza-Chaverri J, Leon-Aparicio D, Salvador C, Sampieri A, Escobar LI (2020) "Funny" channels in cardiac mitochondria modulate membrane potential and oxygen consumption. Biochem Biophys Res Commun 524:1030-36. | LEAK ROUTINE | ROX | Intact cells | Rat | Heart |
| Gumpp 2020 Proc Natl Acad Sci U S A | 2020 | Gumpp AM, Boeck C, Behnke A, Bach AM, Ramo-Fernández L, Welz T, Gündel H, Kolassa IT, Karabatsiakis A (2020) Childhood maltreatment is associated with changes in mitochondrial bioenergetics in maternal, but not in neonatal immune cells. Proc Natl Acad Sci U S A 117:24778-84. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Chen 2020 Mol Genet Genomic Med | 2020 | Chen D, Zhao Q, Xiong J, Lou X, Han Q, Wei X, Xie J, Li X, Zhou H, Shen L, Yang Y, Fang H, Lyu J (2020) Systematic analysis of a mitochondrial disease-causing ND6 mutation in mitochondrial deficiency. Mol Genet Genomic Med 8:e1199. | LEAK ROUTINE | Intact cells | Human | Lymphocyte | |
| Herpich 2020 Exp Gerontol | 2020 | Herpich C, Franz K, Klaus S, Müller-Werdan U, Ost M, Norman K (2020) Age-related fatigue is associated with reduced mitochondrial function in peripheral blood mononuclear cells. Exp Gerontol 144:111177. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Coppin 2020 Cell Death Dis | 2020 | Coppin L, Jannin A, Ait Yahya E, Thuillier C, Villenet C, Tardivel M, Bongiovanni A, Gaston C, de Beco S, Barois N, van Seuningen I, Durand E, Bonnefond A, Vienne JC, Vamecq J, Figeac M, Vincent A, Delacour D, Porchet N, Pigny P (2020) Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface. Cell Death Dis 11:360. | LEAK ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells Intact cells | Human | Islet cell;pancreas;thymus Endothelial;epithelial;mesothelial cell |
| Shimakawa 2020 Int J Mol Sci | 2020 | Shimakawa G, Kohara A, Miyake C (2020) Characterization of light-enhanced respiration in cyanobacteria. Int J Mol Sci 22:342. https://doi.org/10.3390/ijms22010342 | ROUTINE | Intact cells | Eubacteria | ||
| Kahancova 2020 Sci Rep | 2020 | Kahancová A, Sklenář F, Ježek P, Dlasková A (2020) Overexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells. Sci Rep 10:1551. | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
| Owiredu 2020 Toxicol Rep | 2020 | Owiredu S, Ranganathan A, Greenwood JC, Piel S, Janowska JI, Eckmann DM, Kelly M, Ehinger JK, Kilbaugh TJ, Jang DH (2020) In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning. Toxicol Rep 7:1263-71. | ROUTINE ET | CIV ROX | Intact cells | Human | Blood cells Other cell lines |
| Jaber 2020 BM Exp Neurol | 2020 | Jaber SM, Yadava N, Polster BM (2020) Mapping mitochondrial respiratory chain deficiencies by respirometry: beyond the Mito Stress Test. BM Exp Neurol 328:113282. | LEAK ROUTINE ET | ROX | Intact cells | Nervous system | |
| Anand 2020 Toxicol In Vitro | 2020 | Anand CR, Bhavya B, Jayakumar K, Harikrishnan VS, Gopala S (2020) Inorganic nitrite alters mitochondrial dynamics without overt changes in cell death and mitochondrial respiration in cardiomyoblasts under hyperglycemia. Toxicol In Vitro 70:105048. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Heart |
| Alston 2020 Am J Hum Genet | 2020 | Alston CL, Veling MT, Heidler J, Taylor LS, Alaimo JT, Sung AY, He L, Hopton S, Broomfield A, Pavaine J, Diaz J, Leon E, Wolf P, McFarland R, Prokisch H, Wortmann SB, Bonnen PE, Wittig I, Pagliarini DJ, Taylor RW (2020) Pathogenic bi-allelic mutations in NDUFAF8 cause Leigh syndrome with an isolated complex I deficiency. Am J Hum Genet 106:92-101. | LEAK ROUTINE OXPHOS ET | N NS | Permeabilized cells Intact cells | Human | Fibroblast |
| Silva Ferraz 2020 Biochem Pharmacol | 2020 | Silva Ferraz L, Torres da Costa R, Alves da Costa C, Augusto João Ribeiro C, Costa Arruda D, Stuchi Maria-Engler S, Rodrigues T (2020) Targeting mitochondria in melanoma: interplay between MAPK signaling pathway and mitochondrial dynamics . Biochem Pharmacol 178:114104. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
| Al-Azab 2020 FEBS J | 2020 | Al-Azab M, Qaed E, Ouyang X, Elkhider A, Walana W, Li H, Li W, Tang Y, Adlat S, Wei J, Wang B, Li X (2020) TL1A/TNFR2-mediated mitochondrial dysfunction of fibroblast-like synoviocytes increases inflammatory response in patients with rheumatoid arthritis via reactive oxygen species generation. FEBS J 287:3088-104. | LEAK ROUTINE OXPHOS ET | N ROX | Permeabilized cells Intact cells | Human | Other cell lines |
| Messner 2020 Thesis | 2020 | Messner M (2020) Sorafenib resistance of hepatocellular carcinoma. PhD Thesis 130. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
| McCann 2020 Metabolites | 2020 | McCann MR, McHugh CE, Kirby M, Jennaro TS, Jones AE, Stringer KA, Puskarich MA (2020) A multivariate metabolomics method for estimating platelet mitochondrial oxygen consumption rates in patients with sepsis. Metabolites 10:E139. | LEAK ROUTINE ET | ROX | Intact cells | Human | Platelet |
| Truong 2020 Cytokine | 2020 | Truong NTT, Lydic TA, Bazil JN, Suryadevara A, Olson LK (2020) Regulation of lipid metabolism in pancreatic beta cells by interferon gamma: a link to anti-viral function. Cytokine 133:155147. | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
| Mann 2020 Sci Rep | 2020 | Mann J, Yang N, Montpetit R, Kirschenman R, Lemieux H, Goping IS (2020) BAD sensitizes breast cancer cells to docetaxel with increased mitotic arrest and necroptosis. https://doi.org/10.1038/s41598-019-57282-1 | LEAK ROUTINE ET | Intact cells | Human | Other cell lines | |
| Mayoral-Varo 2020 PLoS One | 2020 | Mayoral-Varo V, Calcabrini A, Sánchez-Bailón MP, Martínez-Costa ÓH, González-Páramos C, Ciordia S, Hardisson D, Aragón JJ, Fernández-Moreno MÁ, Martín-Pérez J (2020) c-Src functionality controls self-renewal and glucose metabolism in MCF7 breast cancer stem cells . PLoS One 15:e0235850. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
| Janowska 2020 Toxicol In Vitro | 2020 | Janowska JI, Piel S, Saliba N, Kim CD, Jang DH, Karlsson M, Kilbaugh TJ, Ehinger JK (2020) Mitochondrial respiratory chain Complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug carbamate toxicity and treatment. Toxicol In Vitro 65:104794. | LEAK ROUTINE ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet Blood cells |
| Zulkifli 2020 Nat Commun | 2020 | Zulkifli M, Neff JK, Timbalia SA, Garza NM, Chen Y, Watrous JD, Murgia M, Trivedi PP, Anderson SK, Tomar D, Nilsson R, Madesh M, Jain M, Gohil VM (2020) Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism. Nat Commun 11:4866. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
| Hayes 2020 Nutrients | 2020 | Hayes P, Fergus C, Ghanim M, Cirzi C, Burtnyak L, McGrenaghan CJ, Tuorto F, Nolan DP, Kelly VP (2020) Queuine micronutrient deficiency promotes Warburg metabolism and reversal of the mitochondrial ATP synthase in HeLa cells. Nutrients 12:E871. | LEAK ROUTINE OXPHOS ET | N S Gp CIV ROX | Permeabilized cells Intact cells | Human | HeLa |
| Rocha 2020 Sci Adv | 2020 | Rocha AL, de Lima TI, de Souza GP, Corrêa RO, Ferrucci DL, Rodrigues B, Lopes-Ramos C, Nilsson D, Knittel TL, Castro PR, Fernandes MF, Dos Santos Martins F, Parmigiani RB, Silveira LR, Carvalho HF, Auwerx J, Vinolo MAR, Boucher J, Mori MA (2020) Enoxacin induces oxidative metabolism and mitigates obesity by regulating adipose tissue miRNA expression. Sci Adv 6:eabc6250. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fat |
| Karabatsiakis 2020 Transl Psychiatry | 2020 | Karabatsiakis DA, Schönfeldt-Lecuona PDC (2020) Depression, mitochondrial bioenergetics, and electroconvulsive therapy: a new approach towards personalized medicine in psychiatric treatment - a short review and current perspective. Transl Psychiatry 10:226. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Hijazi 2020 J Cell Sci | 2020 | Hijazi I, Knupp J, Chang A (2020) Retrograde signaling mediates an adaptive survival response to endoplasmic reticulum stress. J Cell Sci 133:jcs241539. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
| Chandramouleeswaran 2020 PLoS One | 2020 | Chandramouleeswaran PM, Guha M, Shimonosono M, Whelan KA, Maekawa H, Sachdeva UM, Ruthel G, Mukherjee S, Engel N, Gonzalez MV, Garifallou J, Ohashi S, Klein-Szanto AJ, Mesaros CA, Blair IA, Pellegrino da Silva R, Hakonarson H, Noguchi E, Baur JA, Nakagawa H (2020) Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes. PLoS One 15:e0239625. | ROUTINE OXPHOS | N S CIV ROX | Permeabilized cells Intact cells | Mouse | Endothelial;epithelial;mesothelial cell |
| Xia 2020 Biomed Res Int | 2020 | Xia W, Wang Q, Lu Y, Hu Y, Zhang X, Zhang J, Liu D, Song J, Zhu Z, Liu D, Zhang H (2020) Transient receptor potential channel canonical type 3 deficiency antagonizes myofibroblast transdifferentiation in vivo. Biomed Res Int 2020:1202189. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Pelaez Coyotl 2020 Pharmaceutics | 2020 | Peláez Coyotl EA, Barrios Palacios J, Muciño G, Moreno-Blas D, Costas M, Montiel Montes T, Diener C, Uribe-Carvajal S, Massieu L, Castro-Obregón S, Espinosa OR, Mata Espinosa D, Barrios-Payan J, León Contreras JC, Corzo G, Hernández-Pando R, Del Rio G (2020) Antimicrobial peptide against Mycobacterium tuberculosis that activates autophagy is an effective treatment for tuberculosis. Pharmaceutics 12:E1071. | ROUTINE ET | Intact cells | Mouse | Fibroblast | |
| Liepinsh 2020 Physiol Rep | 2020 | Liepinsh E, Makarova E, Plakane L, Konrade I, Liepins K, Videja M, Sevostjanovs E, Grinberga S, Makrecka-Kuka M, Dambrova M (2020) Low-intensity exercise stimulates bioenergetics and increases fat oxidation in mitochondria of blood mononuclear cells from sedentary adults. Physiol Rep 8:e14489. | LEAK ROUTINE OXPHOS | F N CIV | Permeabilized cells Intact cells | Human | Blood cells |
| Nascimento-Dos-Santos 2020 Biochim Biophys Acta Mol Basis Dis | 2020 | Nascimento-Dos-Santos G, de-Souza-Ferreira E, Lani R, de Faria CC, Araujo VG, Teixeira-Pinheiro LC, de Souza Vasconcelos T, Leandro TG, Santiago MF, Linden R, Galina A, Petrs-Silva H (2020) Neuroprotection from optic nerve injury and modulation of oxidative metabolism by transplantation of active mitochondria to the retina. Biochim Biophys Acta Mol Basis Dis 1866:165686. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Isolated mitochondria Intact cells | Rat | Liver Nervous system |
| Pola 2020 Invest New Drugs | 2020 | Pola M, Kolarova H, Ruzicka J, Zholobenko A, Modriansky M, Mosinger J, Bajgar R (2020) Effects of zinc porphyrin and zinc phthalocyanine derivatives in photodynamic anticancer therapy under different partial pressures of oxygen in vitro. Invest New Drugs 39:89-97. | LEAK ROUTINE ET | ROX | Intact cells | Human | HeLa |
| Piel 2020 PLoS One | 2020 | Piel S, Chamkha I, Dehlin AK, Ehinger JK, Sjövall F, Elmér E, Hansson MJ (2020) Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose. PLoS One 15:e0231173. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Liver Platelet |
| Luevano-Martinez 2020 FEBS Lett | 2020 | Luévano-Martínez LA, Girard RMBM, Alencar MB, Silber AM (2020) ATP regulates the activity of an alternative oxidase in Trypanosoma brucei. FEBS Lett [Epub ahead of print]. | LEAK ROUTINE ET | Intact cells | Protists | ||
| Kuffner 2020 Cells | 2020 | Kuffner K, Triebelhorn J, Meindl K, Benner C, Manook A, Sudria-Lopez D, Siebert R, Nothdurfter C, Baghai TC, Drexler K, Berneburg M, Rupprecht R, Milenkovic VM, Wetzel CH (2020) Major depressive disorder is associated with impaired mitochondrial function in skin fibroblasts. Cells 9:884. doi: 10.3390/cells9040884 | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
| Parker 2020 Thesis | 2020 | Parker EP (2020) The effect of isoleucine supplementation of peripheral blood mononuclear cell metabolism in subjects with type 2 diabetes. URS Thesis 31. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Grewal 2020 Exp Neurol | 2020 | Grewal R, Reutzel M, Dilberger B, Hein H, Zotzel J, Marx S, Tretzel J, Sarafeddinov A, Fuchs C, Eckert GP (2020) Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing. Exp Neurol 328:113248. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
| Mouithys-Mickalad 2020 Chem Biol Interact | 2020 | Mouithys-Mickalad A, Ceusters J, Charif M, El Moualij B, Schoumacher M, Plyte S, Franck T, Bettendorff L, Pirotte B, Serteyn D, de Tullio P (2020) Modulation of mitochondrial respiration rate and calcium-induced swelling by new cromakalim analogues. Chem Biol Interact 331:109272. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Heart |
| Vicentini 2019 Plant Physiol Biochem | 2019 | Vicentini TM, Cavalheiro AH, Dechandt CRP, Alberici LC, Vargas-Rechia CG (2019) Aluminum directly inhibits alternative oxidase pathway and changes metabolic and redox parameters on Jatropha curcas cell culture. Plant Physiol Biochem 136:92-97. | ROUTINE | Intact cells | Plants | ||
| Zhao 2019 Basic Res Cardiol | 2019 | Zhao J, Gao JL, Zhu JX, Zhu HB, Peng X, Jiang M, Fu Y, Xu J, Mao XH, Hu N, Ma MH, Dong DL (2019) The different response of cardiomyocytes and cardiac fibroblasts to mitochondria inhibition and the underlying role of STAT3. Basic Res Cardiol 114:12. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Rat | Heart Fibroblast |
| Moscheni 2019 Cancers (Basel) | 2019 | Moscheni C, Malucelli E, Castiglioni S, Procopio A, De Palma C, Sorrentino A, Sartori P, Locatelli L, Pereiro E, Maier JA, Iotti S (2019) 3D quantitative and ultrastructural analysis of mitochondria in a model of doxorubicin sensitive and resistant human colon carcinoma cells. Cancers (Basel) 11:E1254. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Skrivergaard 2019 Viruses | 2019 | Skrivergaard S, Jensen MS, Rolander TB, Nguyen TBN, Bundgaard A, Nejsum LN, Martensen PM (2019) The cellular localization of the p42 and p46 oligoadenylate synthetase 1 isoforms and their impact on mitochondrial respiration. Viruses 11:E1122. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Human | Other cell lines HeLa |
| Krylova 2019 Mitochondrion | 2019 | Krylova TD, Sheremet NL, Tabakov VY, Lyamzaev KG, Itkis YS, Tsygankova PG, Andreeva NA, Shmelkova MS, Nevinitsyna TA, Kadyshev VV, Zakharova EY (2019) Three rare pathogenic mtDNA substitutions in LHON patients with low heteroplasmy. Mitochondrion 50:139-144. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Zverova 2019 Neuropsychiatr Dis Treat | 2019 | Zvěřová M, Hroudová J, Fišar Z, Hansíková H, Kališová L, Kitzlerová E, Lambertová A, Raboch J (2019) Disturbances of mitochondrial parameters to distinguish patients with depressive episode of bipolar disorder and major depressive disorder. Neuropsychiatr Dis Treat 15:233-40. | LEAK ROUTINE ET | ROX | Intact cells | Human | Platelet Blood cells |
| Gvozdjakova 2019 Bratisl Lek Listy | 2019 | Gvozdjakova A, Sumbalova Z, Kucharska J, Chladekova A, Rausova Z, Vancova O, Komlosi M, Ulicna O, Mojto V (2019) Platelet mitochondrial bioenergetic analysis in patients with nephropathies and non-communicable diseases: a new method. Bratisl Lek Listy 120:630-35. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet Blood cells |
| Trefts 2019 Thesis | 2019 | Trefts E (2019) Integrin linked kinase is critical for hepatic cellular organization, metabolism, and glucoregulation. PhD Thesis 164. | LEAK ROUTINE ET | Intact cells | Mouse | Liver | |
| Pozenel 2019 Cells | 2019 | Pozenel L, Lindenmair A, Schmidt K, Kozlov AV, Grillari J, Wolbank S, Banerjee A, Weidinger A (2019) Critical impact of human amniotic membrane tension on mitochondrial function and cell viability in vitro. Cells 8:E1641. | ROUTINE | Intact cells | Human | Genital | |
| Callegari 2019 J Mol Biol | 2019 | Callegari S, Müller T, Schulz C, Lenz C, Jans DC, Wissel M, Opazo F, Rizzoli SO, Jakobs S, Urlaub H, Rehling P, Deckers M (2019) A MICOS-TIM22 association promotes carrier import into human mitochondria. J Mol Biol 431:2835-51. | LEAK ET ROUTINE | Intact cells | Human | HEK | |
| Benoist 2019 Sci Rep | 2019 | Benoist L, Chadet S, Genet T, Lefort C, Heraud A, Danila MD, Muntean DM, Baron C, Angoulvant D, Babuty D, Bourguignon T, Ivanes F (2019) Stimulation of P2Y11 receptor protects human cardiomyocytes against hypoxia/reoxygenation injury and involves PKCε signaling pathway. Sci Rep 9:11613. | LEAK ROUTINE ET | ROX | Intact cells | Human | Heart |
| Gaiser 2019 Adv Ther (Weinh) | 2019 | Gaiser A, Hafner S, Schmiech M, Büchele B, Schäfer P, Arnim CA, Calzia, E, Feuring‐Buske M, Buske C, Vick B, Jeremias I, Syrovets T, Simmet T (2019) Gold nanoparticles with selective antileukemic activity in vitro and in vivo target mitochondrial respiration. Adv Ther (Weinh) doi:10.1002/adtp.201800149. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Gautam 2019 Sci Rep | 2019 | Gautam D, Tiwari A, Nath Chaurasia R, Dash D (2019) Glutamate induces synthesis of thrombogenic peptides and extracellular vesicle release from human platelets. Sci Rep 9:8346. | ROUTINE ET | Intact cells | Human | Platelet Blood cells | |
| Kladnicka 2019 Physiol Res | 2019 | Kladnická I, Čedíková M, Kripnerová M, Dvořáková J, Kohoutová M, Tůma Z, Müllerová D, Kuncová J (2019) Mitochondrial respiration of adipocytes differentiating from human mesenchymal stem cells derived from adipose tissue. Physiol Res 68:287-96. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fat Stem cells |
| Kulkarni 2019 Haematologica | 2019 | Kulkarni PP, Tiwari A, Singh N, Gautam D, Sonkar VK, Agarwal V, Dash D (2019) Aerobic glycolysis fuels platelet activation: small-molecule modulators of platelet metabolism as anti-thrombotic agents. Haematologica 104:806-18. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
| Blais-Lecours 2019 Am J Respir Cell Mol Biol | 2019 | Blais-Lecours P, Laouafa S, Arias-Reyes C, Santos WL, Joseph V, Burgess JK, Halayko AJ, Soliz J, Marsolais D (2019) Metabolic adaptation of airway smooth muscle cells to a SPHK2 substrate precedes cytostasis. Am J Respir Cell Mol Biol 62:35-42. | LEAK ROUTINE OXPHOS ET | ROX | Intact cells | Human | Other cell lines |
| Castellano-Gonzalez 2019 Neurotox Res | 2019 | Castellano-Gonzalez G, Jacobs KR, Don E, Cole NJ, Adams S, Lim CK, Lovejoy DB, Guillemin GJ (2019) Kynurenine 3-monooxygenase activity in human primary neurons and effect on cellular bioenergetics identifies new neurotoxic mechanisms. Neurotox Res 35:530-41. | LEAK ET ROUTINE | ROX | Intact cells | Human | HEK |
| Teh 2019 Mol Cancer Ther | 2019 | Teh JT, Zhu WL, Newgard CB, Casey PJ, Wang M (2019) Respiratory capacity and reserve predict cell sensitivity to mitochondria inhibitors: mechanism-based markers to identify metformin-responsive cancers. Mol Cancer Ther 18:693-705. | LEAK ROUTINE OXPHOS ET | N S DQ ROX | Intact cells Permeabilized cells Permeabilized tissue | Human Mouse | Other cell lines |
| Lemieux 2019 bioRxiv | 2019 | Lemieux H, Subarsky P, Doblander C, Wurm M, Troppmair J, Gnaiger E (2019) Mitochondrial respiratory function as an early biomarker of apoptosis induced by growth factor removal. bioRxiv doi: https://doi.org/10.1101/151480 . | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Blood cells |
| Thome 2019 Am J Physiol Cell Physiol | 2019 | Thome T, Salyers ZR, Kumar RA, Hahn D, Berru FN, Ferreira LF, Scali ST, Ryan TE (2019) Uremic metabolites impair skeletal muscle mitochondrial energetics through disruption of the electron transport system and matrix dehydrogenase activity. Am J Physiol Cell Physiol 317:C701-13. | LEAK ROUTINE OXPHOS ET | N NS ROX | Isolated mitochondria Intact cells | Mouse | Skeletal muscle |
| Ahmed 2019 Mol Nutr Food Res | 2019 | Ahmed N, Tcheng M, Roma A, Buraczynski M, Jayanth P, Rea K, Akhtar TA, Spagnuolo PA (2019) Avocatin B protects against lipotoxicity and improves insulin sensitivity in diet-induced obesity. Mol Nutr Food Res 63:e1900688. | LEAK ROUTINE ET | N ROX | Intact cells | Mouse Rat | Skeletal muscle Islet cell;pancreas;thymus |
| Veyrat-Durebex 2019 Mol Neurobiol | 2019 | Veyrat-Durebex C, Bris C, Codron P, Bocca C, Chupin S, Corcia P, Vourc'h P, Hergesheimer R, Cassereau J, Funalot B, Andres CR, Lenaers G, Couratier P, Reynier P, Blasco H (2019) Metabo-lipidomics of fibroblasts and mitochondrial-endoplasmic reticulum extracts from ALS patients shows alterations in purine, pyrimidine, energetic, and phospholipid metabolisms. Mol Neurobiol 56:5780-91. | LEAK ET ROUTINE | ROX | Intact cells | Human | Fibroblast |
| Cruz-Gregorio 2019 Biomolecules | 2019 | Cruz-Gregorio A, Aranda-Rivera AK, Aparicio-Trejo OE, Coronado-Martinez I, Pedraza-Chaverri J, Lizano M (2019) E6 oncoproteins from high-risk human papillomavirus induce mitochondrial metabolism in a head and neck squamous cell carcinoma model. Biomolecules 9:E351. | LEAK ROUTINE | CIV ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Pedrotti 2019 Sci Adv | 2019 | Pedrotti S, Caccia R, Neguembor MV, Garcia-Manteiga JM, Ferri G, de Palma C, Canu T, Giovarelli M, Marra P, Fiocchi A, Molineris I, Raso M, Sanvito F, Doglioni C, Esposito A, Clementi E, Gabellini D (2019) The Suv420h histone methyltransferases regulate PPAR-γ and energy expenditure in response to environmental stimuli. Sci Adv 5:eaav1472. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells | Mouse | Fat |
| Tiebe 2019 Sci Rep | 2019 | Tiebe M, Lutz M, Senyilmaz Tiebe D, Teleman AA (2019) Crebl2 regulates cell metabolism in muscle and liver cells. Sci Rep 9:19869. | LEAK OXPHOS ROUTINE | F N Gp ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle Liver |
| Ramalho 2019 J Leukoc Biol | 2019 | Ramalho T, Ramalingam L, Filgueiras L, Festuccia W, Jancar S, Moustaid-Moussa N (2019) Leukotriene-B4 modulates macrophage metabolism and fat loss in type 1 diabetic mice. J Leukoc Biol 106:665-75. | ROUTINE | ROX | Intact cells | Mouse | Macrophage-derived |
| Grauso 2019 Sci Rep | 2019 | Grauso M, Lan A, Andriamihaja M, Bouillaud F, Blachier F (2019) Hyperosmolar environment and intestinal epithelial cells: impact on mitochondrial oxygen consumption, proliferation, and barrier function in vitro. Sci Rep 9:11360. | LEAK ROUTINE OXPHOS ET | N NS | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
| Rocco-Machado 2019 Free Radic Biol Med | 2019 | Rocco-Machado N, Cosentino-Gomes D, Nascimento MT, Paes-Vieira L, Khan YA, Mittra B, Andrews NW, Meyer-Fernandes JR (2019) Leishmania amazonensis ferric iron reductase (LFR1) is a bifunctional enzyme: Unveiling a NADPH oxidase activity. https://doi.org/10.1016/j.freeradbiomed.2019.08.026 | LEAK ROUTINE ET | ROX | Intact organism Intact cells | Protists | |
| Sanchez-de-Diego 2019 iScience | 2019 | Sánchez-de-Diego C, Artigas N, Pimenta-Lopes C, Valer JA, Torrejon B, Gama-Pérez P, Villena JA, Garcia-Roves PM, Rosa JL, Ventura F (2019) Glucose restriction promotes osteocyte specification by activating a PGC-1α-dependent transcriptional program. iScience 15:79-94. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Other cell lines |
| Trefts 2019 Am J Physiol Endocrinol Metab | 2019 | Trefts E, Hughey CC, Lantier L, Lark DS, Boyd KL, Pozzi A, Zent R, Wasserman DH (2019) Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and the postabsorptive response of mice in an age-dependent manner. Am J Physiol Endocrinol Metab 316:1118-35. | LEAK ROUTINE ET | Intact cells | Mouse | Liver | |
| Dilberger 2019 Oxid Med Cell Longev | 2019 | Dilberger B, Baumanns S, Schmitt F, Schmiedl T, Hardt M, Wenzel U, Eckert GP (2019) Mitochondrial oxidative stress impairs energy metabolism and reduces stress resistance and longevity of C. elegans. Oxid Med Cell Longev 2019:6840540. | LEAK ROUTINE ET | N S CIV NS | Isolated mitochondria | Caenorhabditis elegans | |
| Roux 2019 PLoS Pathog | 2019 | Roux A, Leroy H, De Muylder B, Bracq L, Oussous S, Dusanter-Fourt I, Chougui G, Tacine R, Randriamampita C, Desjardins D, Le Grand R, Bouillaud F, Benichou S, Margottin-Goguet F, Cheynier R, Bismuth G, Mangeney M (2019) FOXO1 transcription factor plays a key role in T cell-HIV-1 interaction. https://doi.org/10.1371/journal.ppat.1007669 | LEAK ROUTINE ET | Intact cells | Human | Lymphocyte | |
| Mayer 2019 Lipids | 2019 | Mayer K, Sommer N, Hache K, Hecker A, Reiche S, Schneck E, Weissmann N, Seeger W, Hecker M (2019) Resolvin E1 improves mitochondrial function in human alveolar epithelial cells during severe inflammation. Lipids 54:53-65. | LEAK ROUTINE ET | ROX | Intact cells | Human | Lung;gill Endothelial;epithelial;mesothelial cell Other cell lines |
| Miranda-Silva 2019 Acta Physiologica | 2019 | Miranda-Silva D, Wüst RCI, Conceição G, Gonçalves-Rodrigues P, Gonçalves N, Gonçalves A, Kuster DWD, Leite-Moreira AF, van der Velden J, de Sousa Beleza JM, Magalhães J, Stienen GJM, Falcão-Pires I (2019) Disturbed cardiac mitochondrial and cytosolic calcium handling in a metabolic risk-related rat model of heart failure with preserved ejection fraction. Acta Physiol e13378. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact organ Permeabilized tissue Isolated mitochondria | Rat | Heart |
| Li 2019 Int Urol Nephrol | 2019 | Li Z, Zhou J, Li Y, Yang F, Lian X, Liu W (2019) Mitochondrial TRPC3 promotes cell proliferation by regulating the mitochondrial calcium and metabolism in renal polycystin-2 knockdown cells. Int Urol Nephrol 51:1059-70. | ROUTINE OXPHOS ET LEAK | N S CIV NS ROX | Intact cells Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
| Chen 2019 Ecotoxicol Environ Saf | 2019 | Chen H, Liu G, Qiao N, Kang Z, Hu L, Liao J, Yang F, Pang C, Liu B, Zeng Q, Li Y, Li Y (2019) Toxic effects of arsenic trioxide on spermatogonia are associated with oxidative stress, mitochondrial dysfunction, autophagy and metabolomic alterations. Ecotoxicol Environ Saf 190:110063. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Genital |
| Esteves 2019 Oncogene | 2019 | Esteves P, Dard L, Brillac A, Hubert C, Sarlak S, Rousseau B, Dumon E, Izotte J, Bonneu M, Lacombe D, Dupuy JW, Amoedo N, Rossignol R (2019) Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F. Oncogene 39:617-36. | LEAK ROUTINE OXPHOS ET | N ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Aubin 2019 Thesis | 2019 | Aubin M (2019) Glucocorticoids and acute lymphoid leukemia: a proteomic approach. Doctoral Dissertation 99. | ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Lymphocyte |
| Di Marcello 2019 MitoFit Preprint Arch EA | 2019 | Di Marcello M, Iglesias-Gonzalez J, Meszaros A, Haider M, Gnaiger E, Huete-Ortega M (2019) Partitioning between cytochrome c oxidase and alternative oxidase studied by oxygen kinetics of dark respiration in Chlamydomonas reinhardtii: a microalgae model organism. https://doi.org/10.26124/mitofit:ea19.MiPSchool.0005.v3 | ROUTINE | Intact cells | Plants | ||
| Winnica 2019 Antioxid Redox Signal | 2019 | Winnica D, Corey C, Mullett S, Reynolds M, Hill G, Wendell S, Que L, Holguin F, Shiva S (2019) Bioenergetic differences in the airway epithelium of lean versus obese asthmatics are driven by nitric oxide and reflected in circulating platelets. Antioxid Redox Signal 31:673–86. | ROUTINE ET | Intact cells | Human | Lung;gill Endothelial;epithelial;mesothelial cell Blood cells Platelet | |
| Malagrino 2019 Oxid Med Cell Longev | 2019 | Malagrinò F, Zuhra K, Mascolo L, Mastronicola D, Vicente JB, Forte E, Giuffrè A (2019) Hydrogen sulfide oxidation: adaptive changes in mitochondria of SW480 colorectal cancer cells upon exposure to hypoxia. Oxid Med Cell Longev 2019:8102936. | ROUTINE | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Devaux 2019 J Exp Biol | 2019 | Devaux JBL, Hickey AJR, Renshaw GMC (2019) Mitochondrial plasticity in the cerebellum of two anoxia-tolerant sharks: contrasting responses to anoxia/reoxygenation. J Exp Biol 222:jeb191353. | LEAK ROUTINE OXPHOS ET | N S NS | Homogenate | Fishes | Nervous system |
| Nunes 2019 Oxid Med Cell Longev | 2019 | Nunes MEM, Schimith LE, da Costa-Silva DG, Lopes AR, Leandro LP, Martins IK, de Mello RS, Hartmann DD, de Carvalho NR, Carvalho da Rosa P, Trevisan R, Di Giulio RT, Posser T, Franco JL (2019) Acute exposure to permethrin modulates behavioral functions, redox, and bioenergetics parameters and induces DNA damage and cell death in larval zebrafish. Oxid Med Cell Longev 2019:9149203. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Homogenate | Zebrafish | |
| Jaskiewicz 2019 J Clin Med | 2019 | Jaśkiewicz A, Pająk B, Łabieniec-Watała M, De Palma C, Orzechowski A (2019) Diverse action of selected statins on skeletal muscle cells - An attempt to explain the protective effect of geranylgeraniol (GGOH) in statin-associated myopathy (SAM). J Clin Med 8:694. | ROUTINE OXPHOS ET LEAK | N S NS ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle Other cell lines |
| Alvarez 2019 Chem Biol Interact | 2019 | Álvarez Santos MR, Duarte YB, Güiza FM, Romero Bohórquez AR, Mendez-Sanchez SC (2019) Effects of new tetrahydroquinoline-isoxazole hybrides on bioenergetics of hepatocarcinoma Hep-G2 cells and rat liver mitochondria. Chem Biol Interact 302:164-71. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
| Ejarque 2019 Int J Obes (Lond) | 2019 | Ejarque M, Ceperuelo-Mallafré V, Serena C, Maymo-Masip E, Duran X, Díaz-Ramos A, Millan-Scheiding M, Núñez-Álvarez Y, Núñez-Roa C, Gama P, Garcia-Roves PM, Peinado MA, Gimble JM, Zorzano A, Vendrell J, Fernández-Veledo S (2019) Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells. Int J Obes (Lond) 43:1256-68. | LEAK ROUTINE ET | Intact cells | Human | Fat | |
| Nold 2019 Psychoneuroendocrinology | 2019 | Nold V, Sweatman C, Karabatsiakis A, Böck C, Bretschneider T, Lawless N, Fundel-Clemens K, Kolassa IT, Allers KA (2019) Activation of the kynurenine pathway and mitochondrial respiration to face allostatic load in a double-hit model of stress. Psychoneuroendocrinology 107:148-59. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
| Kluckova 2019 FASEB J | 2019 | Kluckova K, Thakker A, Vettore L, Escribano-Gonzalez C, Hindshaw RL, Tearle JLE, Goncalves J, Kaul B, Lavery GG, Favier J, Tennant DA (2019) Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function. FASEB J 34:303-315. | LEAK ROUTINE OXPHOS ET | F N NS ROX | Permeabilized cells Intact cells | Mouse | Nervous system |
| Mishra 2019 Bio Protoc | 2019 | Mishra P, Zhang T, Guo M, Chan D (2019) Mitochondrial respiratory measurements in patient-derived fibroblasts. Bio Protoc 9:e3446. doi: 10.21769/BioProtoc.3446 | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
| Mann 2019 Oncogene | 2019 | Mann J, Githaka JM, Buckland TW, Yang N, Montpetit R, Patel N, Li L, Baksh S, Godbout R, Lemieux H, Goping IS (2019) Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism. Oncogene 38:3325-39. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX F | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Kumar 2019 Free Radic Biol Med | 2019 | Kumar A, Davuluri G, Welch N, Kim A, Gangadhariah M, Allawy A, Priyadarshini A, McMullen MR, Sandlers Y, Willard B, Hoppel CL, Nagy LE, Dasarathy S (2019) Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysregulated protein synthesis and autophagy. Free Radic Biol Med 145:284-99. | LEAK ROUTINE OXPHOS ET | F N S DQ CIV NS ROX | Permeabilized cells Permeabilized tissue Intact cells | Mouse | Skeletal muscle |
| Calabria 2019 Front Neurosci | 2019 | Calabria Elisa, Scambi Ilaria, Bonafede Roberta, Schiaffino Lorenzo, Peroni Daniele, Potrich Valentina, Capelli Carlo, Schena Federico, Mariotti Raffaella (2019) ASCs-exosomes recover coupling efficiency and mitochondrial membrane potential in an in vitro model of ALS. Front Neurosci 13:1070. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Mouse | Nervous system |
| Itkis 2019 Mitochondrion | 2019 | Itkis Y, Krylova T, Pechatnikova NL, De Grassi A, Tabakov VY, Pierri CL, Aleshin V, Boyko A, Bunik VI, Zakharova EY (2019) A novel variant m.641A>T in the mitochondrial MT-TF gene is associated with epileptic encephalopathy in adolescent. Mitochondrion 47:10-17. | LEAK ROUTINE OXPHOS ET | N CIV NS ROX | Intact cells Permeabilized cells | Human | Fibroblast |
| Desquiret-Dumas 2019 Biochim Biophys Acta Mol Basis Dis | 2019 | Desquiret-Dumas V, Leman G, Wetterwald C, Chupin S, Lebert A, Khiati S, Le Mao M, Geffroy G, Kane MS, Chevrollier A, Goudenege D, Gadras C, Tessier L, Barth M, Leruez S, Amati-Bonneau P, Henrion D, Bonneau D, Procaccio V, Reynier P, Lenaers G, Gueguen N (2019) Warburg-like effect is a hallmark of complex I assembly defects. Biochim Biophys Acta Mol Basis Dis 1865:2475-89. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Braganza 2019 JCI Insight | 2019 | Braganza A, Corey CG, Santanasto AJ, Distefano G, Coen PM, Glynn NW, Nouraie SM, Goodpaster BH, Newman AB, Shiva S (2019) Platelet bioenergetics correlate with muscle energetics and are altered in older adults. JCI Insight 5:128248. | LEAK OXPHOS ET ROUTINE | N NS | Permeabilized tissue Intact cells | Human | Skeletal muscle Blood cells Platelet |
| Jeon 2019 Sci Rep | 2019 | Jeon AB, Ackart DF, Li W, Jackson M, Melander RJ, Melander C, Abramovitch RB, Chicco AJ, Basaraba RJ, Obregón-Henao A (2019) 2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain. Sci Rep 9:1513. | ROUTINE | Intact cells | Eubacteria | ||
| Oses 2019 Epilepsy Res | 2019 | Oses JP, Müller AP, Strogulski NR, Moreira JD, Böhmer AE, Hansel G, Carteri RB, Busnello JV, Kopczynski A, Rodolphi MS, Souza DO, Portela LV (2019) Sustained elevation of cerebrospinal fluid glucose and lactate after a single seizure does not parallel with mitochondria energy production. Epilepsy Res 152:35-41. | LEAK OXPHOS ROUTINE | N CIV NS | Homogenate | Rat | Nervous system |
| Qaed 2019 Oxid Med Cell Longev | 2019 | Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, Alademi S, Alademi M, Li H, Alshwmi M, Al-Azab M, Ahsan A, Mahdi S, Han G, Niu M, Ali A, Shopit A, Wang H, Li X, Qaid A, Ma X, Li T, Peng J, Ma J, Zhang J, Tang Z (2019) Phosphocreatine improves cardiac dysfunction by normalizing mitochondrial respiratory function through JAK2/STAT3 signaling pathway in vivo and in vitro. Oxid Med Cell Longev 2019:6521218. | LEAK OXPHOS ET ROUTINE | N S NS ROX | Homogenate Isolated mitochondria Permeabilized cells Intact cells | Rat | Heart |
| Lauridsen 2019 Mitochondrion | 2019 | Lauridsen PE, Rasmussen LJ, Desler C (2019) Mitochondrial oxidative phosphorylation capacity of cryopreserved cells. Mitochondrion 47:47-53. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
| Wang H 2019 J Biol Chem | 2019 | Wang H, Lu J, Kulkarni S, Zhang W, Gorka JE, Mandel JA, Goetzman ES, Prochownik EV (2019) Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation in fibroblasts. J Biol Chem 294:5466-86. | ROUTINE OXPHOS ET | F N S NS | Permeabilized cells Isolated mitochondria Intact cells | Rat | Fibroblast |
| Wolf 2019 Cells | 2019 | Wolf C, Zimmermann R, Thaher O, Bueno D, Wüllner V, Schäfer MKE, Albrecht P, Methner A (2019) The Charcot-Marie tooth disease mutation R94Q in MFN2 decreases ATP production but increases mitochondrial respiration under conditions of mild oxidative stress. Cells 8:E1289. | LEAK ROUTINE ET OXPHOS | ROX N NS | Intact cells Permeabilized cells | Mouse | Fibroblast |
| Mueller 2019 Thesis | 2019 | Müller T (2019) Role of MICOS for mitochondrial morphology and function. PhD Thesis 77. | LEAK ROUTINE ET | Intact cells | Human | HEK | |
| Adeyemi 2019 Ecotoxicol Environ Saf | 2019 | Adeyemi JA, Machado ART, Ogunjimi AT, Alberici LC, Antunes LMG, Barbosa F Jr (2019) Cytotoxicity, mutagenicity, oxidative stress and mitochondrial impairment in human hepatoma (HepG2) cells exposed to copper oxide, copper-iron oxide and carbon nanoparticles. Ecotoxicol Environ Saf 189:109982. | LEAK ROUTINE ET | Intact cells | Human | Liver | |
| Gustafson 2019 PLoS One | 2019 | Gustafson MA, McCormick EM, Perera L, Longley MJ, Bai R, Kong J, Dulik M, Shen L, Goldstein AC, McCormack SE, Laskin BL, Leroy BP, Ortiz-Gonzalez XR, Ellington MG, Copeland WC, Falk MJ (2019) Mitochondrial single-stranded DNA binding protein novel de novo SSBP1 mutation in a child with single large-scale mtDNA deletion (SLSMD) clinically manifesting as Pearson, Kearns-Sayre, and Leigh syndromes. PLoS One 14:e0221829. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast Lymphocyte |
| Diebold 2019 Nat Metab | 2019 | Diebold LP, Gil HJ, Gao P, Martinez CA, Weinberg SE, Chandel NS (2019) Mitochondrial Complex III is necessary for endothelial cell proliferation during angiogenesis. Nat Metab 1:158–71. | LEAK ROUTINE | ROX | Intact cells | Human | HUVEC |
| Zhang 2019 Nephron | 2019 | Zhang R, Wang X, Gao Q, Jiang H, Zhang S, Lu M, Liu F, Xue X (2019) Taurine supplementation reverses diabetes-induced podocytes injury via modulation of the CSE/TRPC6 axis and improvement of mitochondrial function. Nephron 144:84-95. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Intact cells Permeabilized cells | Mouse | Kidney |
| Zhao 2019 Pharmacol Res | 2019 | Zhao X, Jin Y, Li L, Xu L, Tang Z, Qi Y, Yin L, Peng J (2019) MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1. Pharmacol Res 146:104276. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Liver Other cell lines |
| Dannheisig 2019 Cells | 2019 | Dannheisig DP, Beck E, Calzia E, Walther P, Behrends C, Pfister AS (2019) Loss of Peter Pan (PPAN) affects mitochondrial homeostasis and autophagic flux. Cells 8:E894. | LEAK ROUTINE ET | N S CIV NS ROX | Intact cells Permeabilized cells | Human | HeLa |
| Hall 2019 Methods Mol Biol | 2019 | Hall A, Moghimi SM (2019) Determination of polycation-mediated perturbation of mitochondrial respiration in intact cells by high-resolution respirometry (Oxygraph-2k, OROBOROS). Methods Mol Biol 1943:313-22. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| Gao 2019 Cancer Cell Int | 2019 | Gao Y, Dorn P, Liu S, Deng H, Hall SRR, Peng RW, Schmid RA, Marti TM (2019) Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment. Cancer Cell Int 19:317. | ROUTINE | Intact cells | Human | Lung;gill Endothelial;epithelial;mesothelial cell | |
| Reyes-Fermin 2019 Antioxidants (Basel) | 2019 | Reyes-Fermín LM, Avila-Rojas SH, Aparicio-Trejo OE, Tapia E, Rivero I, Pedraza-Chaverri J (2019) The protective effect of alpha-mangostin against cisplatin-induced cell death in LLC-PK1 cells is associated to mitochondrial function preservation. Antioxidants (Basel) 8:E133. | LEAK ROUTINE ET | CIV ROX | Intact cells | Pig | Kidney |
| Djeungoue-Petga 2019 Cell Death Dis | 2019 | Djeungoue-Petga MA, Lurette O, Jean S, Hamel-Côté G, Martín-Jiménez R, Bou M, Cannich A, Roy P, Hebert-Chatelain E (2019) Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells. Cell Death Dis 10:940. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
| MiPNet12.01 Suppl T-issue | 2018-11-18 | | LEAK ROUTINE ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Cronin 2018 Nature | 2018 | Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563:564-68. | ROUTINE OXPHOS ET LEAK | N S | Permeabilized cells Intact cells | Mouse | Lymphocyte |
| Zhou 2018 Cell Death Dis | 2018 | Zhou C, Sun H, Zheng C, Gao J, Fu Q, Hu N, Shao X, Zhou Y, Xiong J, Nie K, Zhou H, Shen L, Fang H, Lyu J (2018) Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth. Cell Death Dis 9:161. | LEAK ROUTINE | ROX | Intact cells | Human | Islet cell;pancreas;thymus Other cell lines |
| Tillmans 2018 Thesis | 2018 | Tillmans F (2018) Effect of normobaric hypoxia on leukemic vell lines in vitro. Dissertation p92. | LEAK ROUTINE ET | N S NS ROX | Intact cells Permeabilized cells | Human | Other cell lines Lymphocyte |
| Giacco 2018 FASEB J | 2018 | Giacco A, Delli Paoli G, Senese R, Cioffi F, Silvestri E, Moreno M, Ruoppolo M, Caterino M, Costanzo M, Lombardi A, Goglia F, Lanni A, de Lange P (2018) The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells. FASEB J 33:1811-23. | LEAK ET ROUTINE | ROX | Intact cells | Rat | Skeletal muscle |
| Doerrier 2018 Methods Mol Biol | 2018 | Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. https://doi.org/10.1007/978-1-4939-7831-1_3 | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells | Human Mouse Rat Saccharomyces cerevisiae | Heart Skeletal muscle Endothelial;epithelial;mesothelial cell Blood cells HEK Platelet |
| Li 2018 Free Radic Biol Med | 2018 | Li H, Tang Z, Chu P, Song Y, Yang Y, Sun B, Niu M, Qaed E, Shopit A, Han G, Ma X, Peng J, Hu M, Tang Z (2018) Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways. Free Radic Biol Med 120:228-38. | LEAK ROUTINE ET | CIV | Intact cells | Rat | Nervous system Other cell lines |
| Gatterer 2018 J Sports Sci Med | 2018 | Gatterer H, Menz V, Salazar-Martinez E, Sumbalova Z, Garcia-Souza LF, Cizmarova B, Gnaiger E, Burtscher M (2018) Exercise performance, muscle oxygen extraction and blood cell mitochondrial respiration after repeated-sprint and sprint interval training in hypoxia: a pilot study. J Sports Sci Med 17:339-347. | ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
| Chou 2018 Int J Cardiol | 2018 | Chou CH, Fu TC, Tsai HH, Hsu CC, Wang CH, Wang JS (2018) High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure. Int J Cardiol 274:214-20. | LEAK ROUTINE OXPHOS ET | F N S NS ROX | Intact cells Permeabilized cells | Human | Platelet Blood cells |
| Walczak 2018 FASEB J | 2018 | Walczak J, Dębska-Vielhaber G, Vielhaber S, Szymański J, Charzyńska A, Duszyński J, Szczepanowska J (2018) Distinction of sporadic and familial forms of ALS based on mitochondrial characteristics. FASEB J 33:4388-403. | OXPHOS LEAK ROUTINE | N S | Permeabilized cells | Human | Fibroblast |
| Clere-Jehl 2018 Shock | 2018 | Clere-Jehl R, Helms J, Kassem M, Le Borgne P, Delabranche X, Charles AL, Geny B, Meziani F, Bilbault P (2018) Septic shock alters mitochondrial respiration of lymphoid cell-lines and human peripheral blood mononuclear cells: the role of plasma. Shock 51:97-104. | LEAK ROUTINE ET | Intact cells | Human | Blood cells | |
| Silaidos 2018 Biol Sex Differ | 2018 | Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP (2018) Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain. Biol Sex Differ 9:34. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Nervous system Blood cells |
| Oemer 2018 Proc Nat Acad Sci U S A | 2018 | Oemer G, Lackner L, Muigg K, Krumschnabel G, Watschinger K, Sailer S, Lindner H, Gnaiger E, Wortmann SB, Werner ER, Zschocke J, Keller MA (2018) The molecular structural diversity of mitochondrial cardiolipins. Proc Nat Acad Sci U S A 115:4158-63. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Intact cells Permeabilized cells | Human | HeLa |
| Banerjee 2018 Stem Cells Int | 2018 | Banerjee A, Lindenmair A, Steinborn R, Dumitrescu SD, Hennerbichler S, Kozlov AV, Redl H, Wolbank S, Weidinger A (2018) Oxygen tension strongly influences metabolic parameters and the release of interleukine-6 of human amniotic mesenchymal stromal cells in vitro. Stem Cells Int 2018:9502451. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Genital | |
| Doucet 2018 Mol Pharmacol | 2018 | Doucet MS, Jougleux JL, Poirier SJ, Cormier M, Leger JL, Surette ME, Pichaud N, Touaibia M, Boudreau LH (2018) Identification of peracetylated quercetin as a selective 12-lipoxygenase pathway inhibitor in human platelets. Mol Pharmacol 95:139-50. | LEAK ROUTINE ET | ROX | Intact cells | Human | Platelet Blood cells |
| Rodriguez-Nuevo 2018 EMBO J | 2018 | Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A (2018) Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency. EMBO J 37. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
| Pineda 2018 PLoS Pathog | 2018 | Pineda E, Thonnus M, Mazet M, Mourier A, Cahoreau E, Kulyk H, Dupuy JW, Biran M, Masante C, Allmann S, Rivière L, Rotureau B, Portais JC, Bringaud F (2018) Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions. PLoS Pathog 14:e1007412. | ROUTINE | Intact cells | Protists | ||
| Boeck 2018 Psychoneuroendocrinology | 2018 | Boeck C, Gumpp AM, Calzia E, Radermacher P, Waller C, Karabatsiakis A, Kolassa IT (2018) The association between cortisol, oxytocin, and immune cell mitochondrial oxygen consumption in postpartum women with childhood maltreatment. Psychoneuroendocrinology 96:69-77. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Blunsom 2018 Biochim Biophys Acta | 2018 | Blunsom NJ, Gomez-Espinosa E, Ashlin TG, Cockcroft S (2018) Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1. Biochim Biophys Acta 1863:284-98. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Heart |
| Deschaseaux 2018 US Patent | 2018 | Deschaseaux F, Guilloton F, Muller S, Sensebe L, Casteilla L, Carriere-Pazat A (2018) Method for obtaining human brown/beige adipocytes . US Patent US20180216070A1. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fat |
| Lica 2018 Stem Cells Dev | 2018 | Lica JJ, Grabe GJ, Heldt M, Misiak M, Bloch P, Serocki M, Switalska M, Wietrzyk J, Baginski M, Hellmann A, Borowski E, Skladanowski A (2018) Cell density-dependent cytological stage profile and its application for a screen of cytostatic agents active towards Leukemic Stem Cells. Stem Cells Dev 27:488-513. | LEAK ROUTINE ET | N | Human Mouse | Heart Blood cells Other cell lines | |
| Banerjee 2018 Cell Transplant | 2018 | Banerjee A*, Lindenmair A, Hennerbichler S, Steindorf P, Steinborn R, Kozlov AV, Redl H, Wolbank S, Weidinger A (2018) Cellular and site-specific mitochondrial characterization of vital human amniotic membrane. Cell Transplant 27:3-11. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Genital | |
| Li 2018 Gene | 2018 | Li Y, Wen S, Li D, Xie J, Wei X, Li X, Liu Y, Fang H, Yang Y, Lyu J (2018) SURF1 mutations in Chinese patients with Leigh syndrome: Novel mutations, mutation spectrum, and the functional consequences. Gene 674:15-24. | LEAK ROUTINE | Intact cells | Human | Blood cells | |
| Kahancova 2018 FEBS Lett | 2018 | Kahancova A, Sklenar F, Jezek P, Dlaskova A (2018) Regulation of glucose-stimulated insulin secretion by ATPase Inhibitory Factor 1 (IF1). FEBS Lett 592:999-1009. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Other cell lines |
| Houghton 2018 Free Radic Biol Med | 2018 | Houghton MJ, Kerimi A, Tumova S, Boyle JP, Williamson G (2018) Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells. Free Radic Biol Med 129:296-309. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
| Machado-Neto 2018 Cell Death Dis | 2018 | Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F (2018) Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. Cell Death Dis 9:311. | LEAK ROUTINE ET | ROX | Intact cells | Human Mouse | Other cell lines |
| Friederich 2018 Nat Commun | 2018 | Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, González C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B Jr, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernández-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK (2018) Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nat Commun 9:4065. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human Fungi | Fibroblast |
| Yepez 2018 PLOS One | 2018 | Yépez VA, Kremer LS, Iuso A, Gusic M, Kopajtich R, Koňaříková E, Nadel A, Wachutka L, Prokisch H, Gagneur J (2018) OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer. https://doi.org/10.1371/journal.pone.0199938 | LEAK ROUTINE ET | Intact cells | |||
| Krug 2018 Thesis | 2018 | Krug KP (2018) Adaptation of metabolism and respiratory chain functions in pulmonary arterial vascular muscle cells under chronic hypoxia: especially considering the cytochrome c oxidase subunit 4 isoform 2. Doctoral Dissertation 136. | LEAK ROUTINE OXPHOS ET | N S CIV ROX | Intact cells Permeabilized cells | Rat | Other cell lines |
| Hecker 2018 Biochim Biophys Acta | 2018 | Hecker M, Sommer N, Foch S, Hecker A, Hackstein H, Witzenrath M, Weissmann N, Seeger W, Mayer K (2018) Resolvin E1 and its precursor 18R-HEPE restore mitochondrial function in inflammation. Biochim Biophys Acta 1863:1016-28. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Ost 2018 Curr Opin Clin Nutr Metab Care | 2018 | Ost M, Doerrier C, Gama-Perez P, Moreno-Gomez S (2018) Analysis of mitochondrial respiratory function in tissue biopsies and blood cells. Curr Opin Clin Nutr Metab Care 21:336-42. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Permeabilized tissue Isolated mitochondria Intact cells | Blood cells Platelet Skeletal muscle Liver Fat | |
| Bombaca 2018 Free Radic Biol Med | 2018 | Bombaça ACS, Viana PG, Santos ACC, Silva TL, Rodrigues ABM, Guimarães ACR, Goulart MOF, Da Silva Júnior EN, Menna-Barreto RFS (2018) Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles. Free Radic Biol Med 130:408-18. | ROUTINE | ROX | Intact organism | Protists | |
| Jang 2018 Shock | 2018 | Jang DH, Orloski CJ, Owiredu S, Shofer FS, Greenwood JC, Eckmann DM (2018) Alterations in mitochondrial function in blood cells obtained from patients with sepsis presenting to an emergency department. Shock 51:580-84. | LEAK ROUTINE ET | ROX | Human | Blood cells | |
| Jang 2018 J Med Toxicol | 2018 | Jang DH, Khatri UG, Mudan A, Love JS, Owiredu S, Eckmann DM (2018) Translational application of measuring mitochondrial functions in blood cells obtained from patients with acute poisoning. J Med Toxicol 14:144-51. | LEAK ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Intact cells Permeabilized cells | Human | Blood cells |
| Furlanetto 2018 Physiol Plant | 2018 | Furlanetto ALDM, Cadena SMSC, Martinez GR, Ferrando B, Stevnsner T, Møller IM (2018) Short-term high temperature treatment reduces viability and inhibits respiration and DNA repair enzymes in Araucaria angustifolia cells. Physiol Plant 166:513-24. | ET ROUTINE | N CIV ROX | Intact cells | Plants | |
| Quispe 2018 Mol Neurobiol | 2018 | Quispe RL, Canto RFS, Jaramillo ML, Barbosa FAR, Braga AL, de Bem AF, Farina M (2018) Design, synthesis, and in vitro evaluation of a novel probucol derivative: protective activity in neuronal cells through GPx upregulation. Mol Neurobiol 55:7619-34. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Nervous system Other cell lines |
| Farias 2018 Int J Biol Macromol | 2018 | Farias CLA, Martinez GR, Cadena SMSC, Mercê ALR, de Oliveira Petkowicz CL, Noleto GR (2018) Cytotoxicity of xyloglucan from Copaifera langsdorffii and its complex with oxovanadium (IV/V) on B16F10 cells. Int J Biol Macromol 121:1019-28. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Endothelial;epithelial;mesothelial cell |
| Mendes 2018 Mol Neurobiol | 2018 | Mendes Lima JP, Rayêe D, Silva-Rodrigues T, Ribeiro Paes Pereira P, Mendonca APM, Rodrigues-Ferreira C, Szczupak D, Fonseca A, Oliveira MF, Souza Lima FR, Lent R, Galina A, Uziel D (2018) Perinatal asphyxia and brain development: mitochondrial damage without anatomical or cellular losses. Mol Neurobiol doi.org/10.1007/s12035-018-1019-7. | LEAK ROUTINE ET | N NS ROX | Intact cells | Rat | Nervous system |
| Boutoual 2018 Scientific Reports | 2018 | Boutoual, R., Meseguer, S., Villarroya, M., Martin-Hernandez, E., Errami, M., Martin, M. A., Casado, M., and Armengod, M. E. (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARgamma-UCP2-AMPK axis. Scientific reports 8, 1163 | LEAK ROUTINE OXPHOS ET | F S Gp | Permeabilized cells Intact cells | Human | Other cell lines Fibroblast |
| Perozeni 2018 Int J Mol Sci | 2018 | Perozeni F, Stella GR, Ballottari M (2018) LHCSR expression under HSP70/RBCS2 promoter as a strategy to increase productivity in microalgae. https://doi.org/10.3390/ijms19010155 | ROUTINE | Algae | |||
| Gao 2018 Free Radic Biol Med | 2018 | Gao JL, Zhao J, Zhu HB, Peng X, Zhu JX, Ma MH, Fu Y, Hu N, Tai Y, Xuan XC, Dong DL (2018) Characterizations of mitochondrial uncoupling induced by chemical mitochondrial uncouplers in cardiomyocytes. Free Radic Biol Med 124:288-98. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Heart |
| Dabbaghizadeh 2018 PLOS ONE | 2018 | Dabbaghizadeh A, Morrow G, Amer YO, Chatelain EH, Pichaud N, Tanguay RM (2018) Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis. PLOS ONE 13:e0193771. | LEAK ROUTINE ET | ROX | Intact cells | Human | HeLa |
| Haschka 2018 Mov Disord | 2018 | Haschka D, Volani C, Stefani A, Tymoszuk P, Mitterling T, Holzknecht E, Heidbreder A, Coassin S, Sumbalova Z, Seifert M, Dichtl S, Theurl I, Gnaiger E, Kronenberg F, Frauscher B, Högl B, Weiss G (2018) Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome. Mov Disord 34:114-23. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
| Scarpelli 2018 J Pineal Res | 2018 | Scarpelli P, Almeida GT, Viçoso KL, Lima WR, Pereira LB, Meissner KA, Wrenger C, Rafaello A, Rizzuto R, Pozzan T, Garcia CRS (2018) Melatonin activate FIS1, DYN1 and DYN2 Plasmodium falciparum related-genes for mitochondria fission: mitoemerald-GFP as a tool to visualize mitochondria structure. J Pineal Res 66:e12484. | LEAK ROUTINE ET | Intact organism | |||
| Miklikova 2018 Physiol Res | 2018 | Miklíková M, Jarkovská D, Čedíková M, Švíglerová J, Kuncová J, Nalos L, Kubíková T, Liška V, Holubová M, Lysák D, Králíčková M, Vištejnová L, Štengl M (2018) Beneficial effects of mesenchymal stem cells on adult porcine cardiomyocytes in non-contact co-culture. Physiol Res 67:619-31. | LEAK ROUTINE ET | Intact cells | Pig | Heart | |
| Sumbalova 2018 Nova Sciences | 2018 | Sumbalová Z, Garcia-Souza LF, Cizmarova B, Volani C, Gnaiger E (2018) Analysis of mitochondrial function in human blood cells. In: Recent advances in mitochondrial medicine and coenzyme Q10. Gvozdjáková A, Cornelissen G, Singh RB eds, Nova Sciences:255-68. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Weber 2018 Int J Mol Sci | 2018 | Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE (2018) Succinate accumulation is associated with a shift of mitochondrial respiratory control and HIF-1α upregulation in PTEN negative prostate cancer cells. Int J Mol Sci 19:2129. | ROUTINE OXPHOS ET | F N S NS Other combinations ROX | Intact cells Permeabilized cells | Human | Genital |
| Velazquez-Villegas 2018 Nat Commun | 2018 | Velazquez-Villegas LA, Perino A, Lemos V, Zietak M, Nomura M, Pols TWH, Schoonjans K (2018) TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue. Nat Commun 9:245. | ROUTINE ET | Intact cells | Mouse | Fat | |
| Harmuth 2018 Front Mol Neurosci | 2018 | Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J (2018) Mitochondrial morphology, function and homeostasis are impaired by expression of an N-terminal calpain cleavage fragment of Ataxin-3. Front Mol Neurosci 11:368. | LEAK ET ROUTINE OXPHOS | N S | Homogenate Intact cells | Mouse | Fibroblast |
| Touat 2018 J Clin Invest | 2018 | Touat M, Sourisseau T, Dorvault N, Chabanon RM, Garrido M, Morel D, Krastev DB, Bigot L, Adam J, Frankum JR, Durand S, Pontoizeau C, Souquère S, Kuo MS, Sauvaigo S, Mardakheh F, Sarasin A, Olaussen KA, Friboulet L, Bouillaud F, Pierron G, Ashworth A, Lombès A, Lord CJ, Soria JC, Postel-Vinay S (2018) DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade. J Clin Invest 128:1671-87. | LEAK ROUTINE ET | Human | Lung;gill Other cell lines | ||
| Dejmek 2018 Physiol Res | 2018 | Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J (2018) Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res 67(Suppl 4):S633-S643. | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Intact cells | Human | Lung;gill Fibroblast |
| Hughey 2018 J Biol Chem | 2018 | Hughey CC, Trefts E, Bracy DP, James FD, Donahue EP, Wasserman DH (2018) Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates. J Biol Chem 293:11944-54. | LEAK ROUTINE ET | Intact cells | Mouse | Liver | |
| Sant'Anna-Silva 2018 Front Oncol | 2018 | Sant'Anna-Silva ACB, Santos GC, Campos SPC, Oliveira Gomes AM, Pérez-Valencia JA, Rumjanek FD (2018) Metabolic profile of oral squamous carcinoma cell lines relies on a higher demand of lipid metabolism in metastatic cells. Front Oncol 8:13. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines Fibroblast |
| Burney 2018 Thesis | 2018 | Burney E (2018) Characterization of mitochondrial metabolism in L6 rat myoblasts. Bachelor's Thesis p50. | LEAK ROUTINE OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells Intact cells | Rat | Other cell lines |
| Abdelwahab 2018 Oncogene | 2018 | Abdelwahab EMM, Pal S, Kvell K, Sarosi V, Bai P, Rue R, Krymskaya V, McPhail D, Porter A, Pongracz JE (2018) Mitochondrial dysfunction is a key determinant of the rare disease lymphangioleiomyomatosis and provides a novel therapeutic target. Oncogene 38:3093-3101. | ROUTINE | ROX | Intact cells | Human | Lung;gill Endothelial;epithelial;mesothelial cell |
| Zhang 2018 J Mol Cell Cardiol | 2018 | Zhang G, Sheng M, Wang J, Teng T, Sun Y, Yang Q, Xu Z (2018) Zinc improves mitochondrial respiratory function and prevents mitochondrial ROS generation at reperfusion by phosphorylating STAT3 at Ser727. J Mol Cell Cardiol 118:169-82. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Isolated mitochondria | Mouse | Heart |
| JanssenDuijghuijsen 2018 Thesis | 2018 | JanssenDuijghuijsen LM (2018) Good, Bad, or Risky? Intestinal permeability to protein: Human and in vitro studies. Doctoral Thesis p154. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
| De Paula Martins 2018 Free Radic Biol Med | 2018 | de Paula Martins R, Ghisoni K, Lim CK, Aguiar AS Jr, Guillemin GJ, Latini A (2018) Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes. Free Radic Biol Med 115:371-82. | ROUTINE | N | Rat | Nervous system | |
| Qu 2018 FASEB J | 2018 | Qu C, Zhang S, Wang W, Li M, Wang Y, van der Heijde-Mulder M, Shokrollahi E, Hakim MS, Raat NJH, Peppelenbosch MP, Pan Q (2018) Mitochondrial electron transport chain complex III sustains hepatitis E virus replication and represents an antiviral target. FASEB J 33:1008-19. | LEAK ROUTINE | CIV ROX | Intact cells | Human | Liver |
| Rubio-Villena 2018 Hum Mol Genet | 2018 | Rubio-Villena C, Viana R, Bonet J, Garcia-Gimeno MA, Casado M, Heredia M, Sanz P (2018) Astrocytes: new players in progressive myoclonus epilepsy of Lafora type. Hum Mol Genet 27:1290-1300. | LEAK ROUTINE ET | ROX | Mouse | Nervous system | |
| Ejarque 2018 Int J Obes (Lond) | 2018 | Ejarque M, Ceperuelo-Mallafré V, Serena C, Maymo-Masip E, Duran X, Díaz-Ramos A, Millan-Scheiding M, Núñez-Álvarez Y, Núñez-Roa C, Gama P, Garcia-Roves PM, Peinado MA, Gimble JM, Zorzano A, Vendrell J, Fernández-Veledo S (2018) Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells. Int J Obes (Lond) 43:1256-68. | LEAK ROUTINE ET | CIV ROX | Intact cells | Human | Fat |
| Szelechowski 2018 Sci Rep | 2018 | Szelechowski M, Amoedo N, Obre E, Léger C, Allard L, Bonneu M, Claverol S, Lacombe D, Oliet S, Chevallier S, Le Masson G, Rossignol R (2018) Metabolic reprogramming in amyotrophic lateral sclerosis. Sci Rep 8:3953. | LEAK ROUTINE ET | F ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
| Kriel 2018 Sci Rep | 2018 | Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348. | LEAK OXPHOS ET ROUTINE | N ROX | Permeabilized cells | Human | Nervous system Other cell lines |
| Monzio Compagnoni 2018 Biochim Biophys Acta Mol Basis Dis | 2018 | Monzio Compagnoni G, Kleiner G, Bordoni A, Fortunato F, Ronchi D, Salani S, Guida M, Corti C, Pichler I, Bergamini C, Fato R, Pellecchia MT, Vallelunga A, Del Sorbo F, Elia A, Reale C, Garavaglia B, Mora G, Albanese A, Cogiamanian F, Ardolino G, Bresolin N, Corti S, Comi GP, Quinzii CM, Di Fonzo A (2018) Mitochondrial dysfunction in fibroblasts of multiple system atrophy. Biochim Biophys Acta Mol Basis Dis 1864:3588-97. | OXPHOS ET ROUTINE | N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Ruas 2018 Sci Rep | 2018 | Ruas JS, Siqueira-Santos ES, Rodrigues-Silva E, Castilho RF (2018) High glycolytic activity of tumor cells leads to underestimation of electron transport system capacity when mitochondrial ATP synthase is inhibited. https://doi.org/10.1038/s41598-018-35679-8 | LEAK ET ROUTINE | N | Permeabilized cells Intact cells | Human | Nervous system Other cell lines |
| Geffroy 2018 Biochim Biophys Acta | 2018 | Geffroy G, Benyahia R, Frey S, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Inisan A, Renaud A, Chevrollier A, Henrion D, Bonneau D, Letournel F, Lenaers G, Reynier P, Procaccio V (2018) The accumulation of assembly intermediates of the mitochondrial complex I matrix arm is reduced by limiting glucose uptake in a neuronal-like model of MELAS syndrome. Biochim Biophys Acta 1864:1596-1608. | ROUTINE ET | N | Intact cells | Human | Nervous system Other cell lines |
| Durand 2018 Blood Purif | 2018 | Durand PY, Nicco C, Serteyn D, Attaf D, Edeas M (2018) Microbiota quality and mitochondrial activity link with occurrence of muscle cramps in hemodialysis patients using citrate dialysate: a pilot study. Blood Purif 46:301-8. | LEAK ROUTINE OXPHOS ET | S ROX | Intact cells | Human | Platelet Blood cells |
| De Godoy 2018 J Biol Chem | 2018 | de Godoy MA, Saraiva LM, de Carvalho LRP, Vasconcelos-Dos-Santos A, Beiral HJV, Ramos AB, Silva LRP, Leal RB, Monteiro VHS, Braga CV, de Araujo-Silva CA, Sinis LC, Bodart-Santos V, Kasai-Brunswick TH, Alcantara CL, Lima APCA, da Cunha-E Silva NL, Galina A, Vieyra A, De Felice FG, Mendez-Otero R, Ferreira ST (2018) Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers. J Biol Chem 293:1957-75. | LEAK ROUTINE ET | Intact cells | Rat | Nervous system | |
| Lee 2018 Reprod Sci | 2018 | Lee HC, Lin SC, Wu MH, Tsai SJ (2018) Induction of pyruvate dehydrogenase kinase 1 by hypoxia alters cellular metabolism and inhibits apoptosis in endometriotic stromal cells. Reprod Sci 26:734-44. | LEAK ROUTINE | ROX | Intact cells | Human | Genital |
| Ma 2018 Nat Cell Biol | 2018 | Ma C, Niu R, Huang T, Shao LW, Peng Y, Ding W, Wang Y, Jia G, He C, Li CY, He A, Liu Y (2018) N6-methyldeoxyadenine is a transgenerational epigenetic signal for mitochondrial stress adaptation. Nat Cell Biol 21:319-27. | ROUTINE | Intact cells | Caenorhabditis elegans | ||
| Dias 2018 Anal Biochem | 2018 | Dias C, Lourenco CF, Barbosa RM, Laranjinha J, Ledo A (2018) Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices. Anal Biochem 551:43-50. | LEAK ROUTINE ET | ROX | Intact cells | Mouse Rat | Nervous system |
| Kong 2018 Proteomics | 2018 | Kong D, Tian X, Li Y*, Zhang S, Cheng Y, Huo L, Ma H, Yang Z, Ren L, Zhang M, Zhang W (2018) Revealing the inhibitory effect of ginseng on mitochondrial respiration through synaptosomal proteomics. Proteomics 18:e1700354. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
| Zhou 2018 Free Radic Biol Med | 2018 | Zhou L, Yi Y, Yuan Q, Zhang J, Li Y, Wang P, Xu M, Xie S (2018) VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via activation of AKT-dependent ROS production in NSCLC. Free Radic Biol Med 129:177-85. | ROUTINE | Intact cells | Human | Lung;gill | |
| Cunatova 2018 Thesis | 2018 | Čunátová K (2018) The role of tissue specific isoforms of subunit 4 in assembly and function of cytochrome c oxidase. PhD Thesis p107. | LEAK ROUTINE ET | CIV ROX | Intact cells | Human | HEK |
| Magnifico 2018 Oxid Med Cell Longev | 2018 | Magnifico MC, Xhani M, Popov M, Saso L, Sarti P, Arese M (2018) Nonylphenol and octylphenol differently affect cell redox balance by modulating the nitric oxide signaling. Oxid Med Cell Longev 2018:1684827. | ROUTINE OXPHOS | N S CIV ROX | Permeabilized cells Intact cells | Human | Liver Other cell lines |
| De Sales 2018 Molecules | 2018 | de Sales NFF, Silva da Costa L, Carneiro TIA, Minuzzo DA, Oliveira FL, Cabral LMC, Torres AG, El-Bacha T (2018) Anthocyanin-rich grape pomace extract (Vitis vinifera L.) from wine industry affects mitochondrial bioenergetics and glucose metabolism in human hepatocarcinoma HepG2 cells. Molecules 23. | LEAK ROUTINE ET | N | Intact cells | Human | Liver Other cell lines |
| Chen 2018 iScience | 2018 | Chen YC, Cheng TH, Lin WL, Chen CL, Yang WY, Blackstone C, Chang CR (2018) Srv2 Is a pro-fission factor that modulates yeast mitochondrial morphology and respiration by regulating actin assembly. iScience 11:305-17. | LEAK ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
| Barca 2018 Hum Mol Genet | 2018 | Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12. | LEAK ROUTINE OXPHOS ET | F N S DQ NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Mancini 2017 Thesis | 2018 | Mancini G (2017) Colesterol dietético e doença de Alzheimer em modelos experimentais: avaliação da resposta sináptica, mitocondrial e comportamental. Doctoral Thesis p118. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Nervous system |
| Quispe 2018 Redox Biol | 2018 | Quispe RL, Jaramillo ML, Galant LS, Engel D, Dafre AL, Teixeira da Rocha JB, Radi R, Farina M, de Bem AF (2018) Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant system. Redox Biol 20:118-29. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Nervous system Other cell lines |
| Fuhrmann 2018 Cell Mol Life Sci | 2018 | Fuhrmann DC, Wittig I, Dröse S, Schmid T, Dehne N, Brüne B (2018) Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia. Cell Mol Life Sci 75:3051-67. | LEAK ROUTINE OXPHOS ET | N S ROX | Isolated mitochondria Intact cells | Human | |
| Bialas 2018 Int J Chron Obstruct Pulmon Dis | 2018 | Białas AJ, Siewiera K, Watała C, Rybicka A, Grobelski B, Kośmider L, Kurek J, Miłkowska-Dymanowska J, Piotrowski WJ, Górski P (2018) Mitochondrial functioning abnormalities observed in blood platelets of chronic smoke-exposed guinea pigs – a pilot study. Int J Chron Obstruct Pulmon Dis 13:3707—17 . | LEAK ROUTINE ET | ROX | Intact cells | Guinea pig | Platelet |
| Rodrigues 2018 Free Radic Biol Med | 2018 | Rodrigues NR, Macedo GE, Martins IK, Gomes KK, de Carvalho NR, Posser T, Franco JL (2018) Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila. Free Radic Biol Med 120:395-406. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Drosophila | |
| Boeck 2018 Sci Rep | 2018 | Boeck C, Salinas-Manrique J, Calzia E, Radermacher P, von Arnim CAF, Dietrich DE, Kolassa IT, Karabatsiakis A (2018) Targeting the association between telomere length and immunocellular bioenergetics in female patients with Major Depressive Disorder. Sci Rep 8:9419. | LEAK ROUTINE ET | N ROX | Intact cells | Human | Blood cells |
| MitoFit Open Seminar 2017-07-14 | 2017-07-14 |  Investigating the role of mitochondria in healthy and psychopathological aging. | LEAK ROUTINE ET | Intact cells | Human | Blood cells | |
| Garcia-Neto 2017 PLOS ONE | 2017 | Garcia-Neto W, Cabrera-Orefice A, Uribe-Carvajal S, Kowaltowski AJ, Luévano-Martínez LA (2017) High osmolarity environments activate the mitochondrial alternative oxidase in Debaryomyces Hansenii. PLOS ONE 12:e0169621. https://doi.org/10.1371/journal.pone.0169621 | ROUTINE | CIV ROX | Isolated mitochondria Intact cells | Fungi | |
| Welker 2017 Thesis | 2017 | Welker L (2017) Metabolic and morphologic shifts in Neuro2a cells cultured in galactose medium. Master's Thesis p26. | LEAK ROUTINE ET | Intact cells | Mouse | ||
| Bernardinelli 2017 PLoS One | 2017 | Bernardinelli E, Costa R, Scantamburlo G, To J, Morabito R, Nofziger C, Doerrier C, Krumschnabel G, Paulmichl M, Dossena S (2017) Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. PLoS One 12(6):e0179591. | LEAK ROUTINE ET | ROX | Intact cells | Human | Kidney |
| Ma 2017 Int J Cancer | 2017 | Ma L, Fu Q, Xu B, Zhou H, Gao J, Shao X, Xiong J, Gu Q, Wen S, Li F, Shen L, Chen G, Fang H, Lyu J (2017) Breast cancer-associated mitochondrial DNA haplogroup promotes neoplastic growth via ROS-mediated AKT activation. Int J Cancer 142:1786-96. | LEAK ROUTINE ET | Intact cells | Human | ||
| Singhal 2017 Mol Biol Cell | 2017 | Singhal RK, Kruse C, Heidler J, Strecker V, Zwicker K, Düsterwald L, Westermann B, Herrmann JM, Wittig I, Rapaport D (2017) Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex. Mol Biol Cell 28:2609-22. | ROUTINE ET | Isolated mitochondria | Saccharomyces cerevisiae | ||
| Goncalves 2017 J Cell Commun Signal | 2017 | Gonçalves R, Zamoner A, Zanatta L, Zanatta AP, Remor AP, da Luz Scheffer D, Latini A, Silva FR (2017) 1,25(OH)2 vitamin D3 signalling on immature rat Sertoli cells: gamma-glutamyl transpeptidase and glucose metabolism. J Cell Commun Signal 11:233-43. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Genital |
| Elmer 2017 US Patent | 2017 | Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1. | LEAK ROUTINE OXPHOS ET | S ROX | Intact cells | Human | Heart Blood cells Fibroblast Macrophage-derived Platelet |
| Ounpuu 2017 Biochim Biophys Acta | 2017 | Ounpuu L, Klepinin A, Pook M, Teino I, Peet N, Paju K, Tepp K, Chekulayev V, Shevchuk I, Koks S, Maimets T, Kaambre T (2017) 2102Ep embryonal carcinoma cells have compromised respiration and shifted bioenergetic profile distinct from H9 human embryonic stem cells. Biochim Biophys Acta 1861:2146-54. | LEAK ROUTINE OXPHOS ET | N S NS ROX CIV | Permeabilized cells Intact cells | Human | Stem cells |
| De Souza 2017 Thesis | 2017 | de Souza LF (2017) Modulação redox de peroxirredoxinas e a participação dos sistemas da GSH e da Trx na proteção/função celular. Tese (doutorado) p103. | LEAK ROUTINE ET | Intact cells | Human | Other cell lines | |
| Lopez 2017 PLOS ONE | 2017 | López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090. | LEAK ROUTINE OXPHOS | N S NS | Isolated mitochondria | Mouse | |
| Friederich 2017 Hum Mol Genet | 2017 | Friederich MW, Erdogan AJ, Coughlin CR 2nd, Elos MT, Jiang H, O'Rourke CP, Lovell MA, Wartchow E, Gowan K, Chatfield KC, Chick WS, Spector EB, Van Hove JLK, Riemer J (2017) Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly. Hum Mol Genet 26:702-16. | ROUTINE OXPHOS ET LEAK | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Permer 2017 Bachelor Thesis | 2017 | Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Intact cells | Human | Other cell lines HEK |
| Lang 2017 Aging (Albany NY) | 2017 | Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP (2017) SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy. Aging (Albany NY) 9:2163-89. | LEAK ET ROUTINE | ROX | Intact cells | Human | Kidney HEK |
| Bansal 2017 Environ Health Perspect | 2017 | Bansal A, Rashid C, Xin F, Li C, Polyak E, Duemler A, van der Meer T, Stefaniak M, Wajid S, Doliba N, Bartolomei MS, Simmons RA (2017) Sex- and dose-specific effects of maternal bisphenol A exposure on pancreatic islets of first- and second-generation adult mice offspring. Environ Health Perspect 125:097022. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Islet cell;pancreas;thymus |
| Blecha 2017 Free Radic Biol Med | 2017 | Blecha J, Novais SM, Rohlenova K, Novotna E, Lettlova S, Schmitt S, Zischka H, Neuzil J, Rohlena J (2017) Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death. Free Radic Biol Med 112:253-66. | ROUTINE OXPHOS | S | Intact cells | Endothelial;epithelial;mesothelial cell | |
| Ruiz 2017 Brain Pathol | 2017 | Ruiz M, Bégou M, Launay N, Ranea-Robles P, Bianchi P, López-Erauskin J, Morató L, Guilera C, Petit B, Vaurs-Barriere C, Guéret-Gonthier C, Bonnet-Dupeyron MN, Fourcade S, Auwerx J, Boespflug-Tanguy O, Pujol A (2017) Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease. Brain Pathol 28:611-30. | LEAK ROUTINE ET | ROX | Intact cells | Human Mouse | Nervous system Fibroblast |
| Phillips 2017 Cancer Res | 2017 | Phillips CM, Zatarain JR, Nicholls ME, Porter C, Widen SG, Thanki K, Johnson P, Jawad MU, Moyer MP, Randall JW, Hellmich JL, Maskey M, Qiu S, Wood TG, Druzhyna N, Szczesny B, Módis K1, Szabo C, Chao C, Hellmich MR. (2017) Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.. Cancer Res. 77(21):5741-5754. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
| Da Silva 2017 Life Sci | 2017 | da Silva MH, Peçanha FLM, de Oliveira AM, da-Silva WS (2017) 4-Phenyl butyric acid increases particulate hexokinase activity and protects against ROS injury in L6 myotubes. Life Sci 179:98-102. | ROUTINE | Intact cells | Rat | Skeletal muscle Other cell lines | |
| Canevarolo 2017 Thesis | 2017 | Canevarolo RR (2017) Resistência ao metotrexato está diretamente associada à concentração de glutationa em linhagens de leucemia linfoide aguda. Dissertation p159. | LEAK ROUTINE ET | Intact cells | Human | Macrophage-derived | |
| Jang 2017 Biol Open | 2017 | Jang DH, Seeger SC, Grady ME, Shofer FC, Eckmann DM (2017) Mitochondrial dynamics and respiration within cells with increased open pore cytoskeletal meshes. Biol Open 6:1831-9. | LEAK ROUTINE ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
| Jang 2017 Clin Toxicol (Phila) | 2017 | Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84. | LEAK ROUTINE OXPHOS ET | F S CIV NS ROX | Intact cells | Blood cells | |
| Jezek 2017 Biochim Biophys Acta | 2017 | Ježek J, Engstová H, Ježek P (2017) Antioxidant mechanism of mitochondria-targeted plastoquinone SkQ1 is suppressed in aglycemic HepG2 cells dependent on oxidative phosphorylation. Biochim Biophys Acta 1858:750-62. | ET ROUTINE | ROX | Intact cells | Human | Liver |
| Saintas 2017 PLOS ONE | 2017 | Saintas E, Abrahams L, Ahmad GT, Ajakaiye AM, AlHumaidi AS, Ashmore-Harris C, Clark I, Dura UK, Fixmer CN, Ike-Morris C, Mato Prado M, Mccullough D, Mishra S, Schöler KM, Timur H, Williamson MD, Alatsatianos M, Bahsoun B, Blackburn E, Hogwood CE, Lithgow PE, Rowe M, Yiangou L, Rothweiler F, Cinatl J Jr, Zehner R, Baines AJ, Garrett MD, Gourlay CW, Griffin DK, Gullick WJ, Hargreaves E, Howard MJ, Lloyd DR, Rossman JS, Smales CM, Tsaousis AD, von der Haar T, Wass MN, Michaelis M (2017) Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS. PLOS ONE 12:e0172140. | LEAK ROUTINE ET | Intact cells | Human | Nervous system Other cell lines | |
| Cunha de Padua 2017 Carbohydr Polym | 2017 | Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Toxicity of native and oxovanadium (IV/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions. Carbohydr Polym 173:665-75. | LEAK ROUTINE ET | ROX | Human | Liver | |
| Wu 2017 Sci Rep | 2017 | Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191. | LEAK OXPHOS ET ROUTINE | N NS ROX CIV | Permeabilized cells Intact cells | Human | Blood cells Platelet |
| Radenkovic 2017 Biochem Pharmacol | 2017 | Radenkovic F, Holland OJ, Vanderlelie JJ, Perkins AV (2017) Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation. Biochem Pharmacol 146:42-52. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Other cell lines |
| Cervoni 2017 J Exp Biol | 2017 | Cervoni MS, Cardoso-Júnior CAM, Craveiro G, Souza AO, Alberici LC, Hartfelder K (2017) Mitochondrial capacity, oxidative damage and hypoxia gene expression are associated with age-related division of labor in honey bee (Apis mellifera L.) workers. J Exp Biol 220:4035-46. | LEAK ROUTINE OXPHOS ET | N ROX | Intact cells | ||
| Rohde 2017 Cell Death Differ | 2017 | Rohde K, Kleinesudeik L, Roesler S, Löwe O, Heidler J, Schröder K, Wittig I, Dröse S, Fulda S (2017) A Bak-dependent mitochondrial amplification step contributes to Smac mimetic/glucocorticoid-induced necroptosis. Cell Death Differ 24:83-97. | LEAK ROUTINE ET | CIV ROX | Intact cells | Mouse | Fibroblast |
| Porter 2017 Adipocyte | 2017 | Porter C (2017) Quantification of UCP1 function in human brown adipose tissue. Adipocyte 6:167-74. | LEAK ROUTINE OXPHOS ET | Permeabilized tissue Isolated mitochondria Intact cells | Fat | ||
| Beresewicz 2017 PLOS ONE | 2017 | Beręsewicz M, Boratyńska-Jasińska A, Charzewski Ł, Kawalec M, Kabzińska D, Kochański A, Krzyśko KA, Zabłocka B (2017) The effect of a novel c.820C>T (Arg274Trp) mutation in the mitofusin 2 gene on fibroblast metabolism and clinical manifestation in a patient. PLOS ONE 12:e0169999. | LEAK ET ROUTINE | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast | |
| Frawley 2017 Chem Res Toxicol | 2017 | Frawley KL, Cronican AA, Pearce LL, Peterson J (2017) Sulfide toxicity and its modulation by nitric oxide in bovine pulmonary artery endothelial cells. Chem Res Toxicol 30:2100-9. | ROUTINE | Intact cells | Bovines | Endothelial;epithelial;mesothelial cell | |
| Favero 2017 Thesis | 2017 | Favero BC (2017) Efeitos da leucina sobre a via da mTOR e da miostatina em cultura celular de miotúbulos. Dissertation p55. | LEAK ROUTINE ET | Mouse | Skeletal muscle | ||
| Cunha 2017 Int J Biol Macromol | 2017 | Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells. Int J Biol Macromol 101:64-473. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
| Cigliano 2017 Mol Neurobiol | 2017 | Cigliano L, Spagnuolo MS, Crescenzo R, Cancelliere R, Iannotta L, Mazzoli A, Liverini G, Iossa S (2017) Short-term fructose feeding induces inflammation and oxidative stress in the hippocampus of young and adult rats. Mol Neurobiol 55:2869-83. | ROUTINE | CIV Other combinations | Homogenate Intact cells | Rat | Nervous system Other cell lines |
| Theisen 2017 Am J Med Genet A | 2017 | Theisen BE, Rumyantseva A, Cohen JS, Alcaraz WA, Shinde DN, Tang S, Srivastava S, Pevsner J, Trifunovic A, Fatemi A (2017) Deficiency of WARS2, encoding mitochondrial tryptophanyl tRNA synthetase, causes severe infantile onset leukoencephalopathy. Am J Med Genet A 173:2505-10. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
| Zhou 2017 Oxid Med Cell Longev | 2017 | Zhou H, Nie K, Qiu R, Xiong J, Shao X, Wang B, Shen L, Lyu J, Fang H (2017) Generation and bioenergetic profiles of cybrids with east Asian mtDNA haplogroups. Oxid Med Cell Longev 2017:1062314. | LEAK ROUTINE | Intact cells | Human | ||
| Morrow 2017 Proc Natl Acad Sci U S A | 2017 | Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC (2017) Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. Proc Natl Acad Sci U S A 114:2705-10. | ROUTINE OXPHOS LEAK | N NS ROX Other combinations | Permeabilized tissue | Skeletal muscle | |
| Scrima 2017 PLOS ONE | 2017 | Scrima R, Menga M, Pacelli C, Agriesti F, Cela O, Piccoli C, Cotoia A, De Gregorio A, Gefter JV, Cinnella G, Capitanio N (2017) Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift. PLOS ONE 12:e0188683. | LEAK ROUTINE ET | ROX | Intact cells | Human Mouse | Endothelial;epithelial;mesothelial cell Blood cells Fibroblast Macrophage-derived |
| Uzhachenko 2017 Aging (Albany NY) | 2017 | Uzhachenko R, Boyd K, Olivares-Villagomez D, Zhu Y, Goodwin JS, Rana T, Shanker A, Tan WJ, Bondar T, Medzhitov R, Ivanova AV (2017) Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasis. Aging (Albany NY) 9:627-49. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Kidney Endothelial;epithelial;mesothelial cell Fibroblast |
| Sidlauskas 2017 Neurosci Lett | 2017 | Sidlauskas K, Sidlauskiene R, Li N, Liobikas J (2017) 5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. Neurosci Lett 639:207-14. | OXPHOS LEAK ROUTINE ET | N S | Intact cells Permeabilized cells | Rat | Nervous system Other cell lines |
| Holland 2017 Placenta | 2017 | Holland OJ, Hickey AJR, Alvsaker A, Moran S, Hedges C, Chamley LW, Perkins AV (2017) Changes in mitochondrial respiration in the human placenta over gestation. Placenta 57:102-12. | LEAK ROUTINE OXPHOS | F N CIV NS ROX | Permeabilized cells Intact cells | Genital | |
| Beresewicz 2017 PLoS One | 2017 | Beresewicz M, Boratynska-Jasinska A, Charzewski L, Kawalec M, Kabzinska D, Kochanski A, Krzysko KA, Zablocka B (2017) The effect of a novel c.820C>T (Arg274Trp) mutation in the mitofusin 2 gene on fibroblast metabolism and clinical manifestation in a patient. PLoS One 12:0169999. | LEAK ET ROUTINE | Intact cells | Human | Fibroblast Endothelial;epithelial;mesothelial cell | |
| Mantilla 2017 PLOS Pathog | 2017 | Mantilla BS, Marchese L, Casas-Sánchez A, Dyer NA, Ejeh N, Biran M, Bringaud F, Lehane MJ, Acosta-Serrano A, Silber AM (2017) Proline metabolism is essential for Trypanosoma brucei brucei survival in the tsetse vector. PLOS Pathog 13:e1006158. | LEAK OXPHOS ET ROUTINE | S ROX N | Permeabilized cells Intact cells | Protists | |
| McFarlane 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | McFarlane SV, Mathers KE, Staples JF (2017) Reversible temperature-dependent differences in brown adipose tissue respiration during torpor in a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 312:R434-42. | LEAK ROUTINE OXPHOS | F N | Isolated mitochondria Intact cells | Other mammals | Fat |
| Miettinen 2017 Trends Cell Biol | 2017 | Miettinen TP, Björklund M (2017) Mitochondrial function and cell size: an allometric relationship. Trends Cell Biol 27:393-402. | ROUTINE | Intact organism Intact cells | |||
| Schaefer 2017 Neurophotonics | 2017 | Schaefer PM, Hilpert D, Niederschweiberer M, Neuhauser L, Kalinina S, Calzia E, Rueck A, von Einem B, von Arnim CAF (2017) Mitochondrial matrix pH as a decisive factor in neurometabolic imaging. Neurophotonics 4:045004. | ROUTINE ET | CIV ROX | Kidney HEK | ||
| Kang 2017 Mol Cell | 2017 | Kang Y, Stroud DA, Baker MJ, De Souza DP, Frazier AE, Liem M, Tull D, Mathivanan S, McConville MJ, Thorburn DR, Ryan MT, Stojanovski D (2017) Sengers Syndrome-associated mitochondrial acylglycerol kinase is a subunit of the human TIM22 protein import complex. Mol Cell 67:457-70. | ROUTINE ET | Intact cells | Human | ||
| Bombaca 2017 Free Radic Biol Med | 2017 | Bombaça ACS, Dias FA, Ennes-Vidal V, Garcia-Gomes ADS, Sorgine MHF, d'Avila-Levy CM, Menna-Barreto RFS (2017) Hydrogen peroxide resistance in Strigomonas culicis: Effects on mitochondrial functionality and Aedes aegypti interaction. Free Radic Biol Med 113:255-66. | ROUTINE | CIV ROX | Intact cells | Protists | |
| Pino 2017 Int J Obes (Lond) | 2017 | Pino MF, Divoux A, Simmonds AV, Smith SR, Sparks LM (2017) Investigating the effects of Orexin-A on thermogenesis in human deep neck brown adipose tissue. Int J Obes (Lond) 41:1646-53. | LEAK ROUTINE | Intact cells | Human | Fat | |
| Schaefer 2017 Thesis | 2017 | Schaefer P (2017) Metabolic imaging in Alzheimer´s disease using NADH autofluorescence. Dissertation p93. | LEAK ET ROUTINE | CIV ROX | Intact cells | Human | HEK Other cell lines |
| Rezania 2017 Thromb Res | 2017 | Rezania S, Puskarich MA, Petrusca DN, Neto-Neves EM, Rondina MT, Kline JA (2017) Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism. Thromb Res 155:106-15. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
| Zeidler 2017 J Biol Chem | 2017 | Zeidler JD, Fernandes-Siqueira LO, Carvalho AS, Cararo-Lopes E, Dias MH, Ketzer LA, Galina A, Da Poian AT (2017) Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria. J Biol Chem 292:14176-87. | LEAK ROUTINE ET | F N ROX | Intact cells | Mouse | |
| Ortega-Dominguez 2017 Food Chem Toxicol | 2017 | Ortega-Domínguez B, Aparicio-Trejo OE, García-Arroyo FE, León-Contreras JC, Tapia E, Molina-Jijón E, Hernández-Pando R, Sánchez-Lozada LG, Barrera-Oviedo D, Pedraza-Chaverri J (2017) Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic. Food Chem Toxicol 107:373-85. | LEAK ROUTINE OXPHOS | N NS | Isolated mitochondria | ||
| Tueller 2017 Biochem Biophys Res Commun | 2017 | Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72. | LEAK ROUTINE OXPHOS | F N NS ROX | Permeabilized cells Intact cells | Skeletal muscle | |
| Davis 2017 Tissue Eng Part C Methods | 2017 | Davis BN, Santoso JW, Walker MJ, Cheng CS, Koves TR, Kraus WE, Truskey GA (2017) Human, tissue-engineered, skeletal muscle myobundles to measure oxygen uptake and assess mitochondrial toxicity. Tissue Eng Part C Methods 23:189-99. | LEAK ROUTINE ET | ROX | Intact cells | Human | Skeletal muscle |
| Seo 2017 Elife | 2017 | Seo AY, Lau PW, Feliciano D, Sengupta P, Gros MAL, Cinquin B, Larabell CA, Lippincott-Schwartz J (2017) AMPK and vacuole-associated Atg14p orchestrate μ-lipophagy for energy production and long-term survival under glucose starvation. Elife 6. pii: e21690. | ROUTINE | Saccharomyces cerevisiae | |||
| Asiri 2017 Thesis | 2017 | Asiri A (2017) Effects of asiatic acid on neurite outgrowth in Neuro-2a cells. Master's Thesis p42. | LEAK ROUTINE ET | Intact cells | Mouse | Nervous system | |
| Pfeiffer 2017 Free Radic Biol Med | 2017 | Pfeiffer A, Schneider J, Bueno D, Dolga A, Voss TD, Lewerenz J, Wüllner V, Methner A (2017) Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity. Free Radic Biol Med 112:350-9. | LEAK ROUTINE OXPHOS ET | N NS ROX | Permeabilized cells | Mouse | Fibroblast |
| Profilo 2017 Biochim Biophys Acta | 2017 | Profilo E, Peña-Altamira LE, Corricelli M, Castegna A, Danese A, Agrimi G, Petralla S, Giannuzzi G, Porcelli V, Sbano L, Viscomi C, Massenzio F, Palmieri EM, Giorgi C, Fiermonte G, Virgili M, Palmieri L, Zeviani M, Pinton P, Monti B, Palmieri F, Lasorsa FM (2017) Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells. Biochim Biophys Acta 1863:1422-35. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Nervous system Other cell lines Neuroblastoma |
| De Carvalho 2017 Sci Rep | 2017 | de Carvalho AETS, Bassaneze V, Forni MF, Keusseyan AA, Kowaltowski AJ, Krieger JE (2017) Early postnatal cardiomyocyte proliferation requires high oxidative energy metabolism. Sci Rep 7:15434. | ROUTINE | Intact cells | Rat | Heart | |
| Thaher 2017 Neurochem Int | 2017 | Thaher O, Wolf C, Dey PN, Pouya A, Wüllner V, Tenzer S, Methner A (2017) The thiol switch C684 in Mitofusin-2 mediates redox-induced alterations of mitochondrial shape and respiration. Neurochem Int 117:167-73. | LEAK ROUTINE OXPHOS ET | N NS ROX | Intact cells Permeabilized cells | Mouse | Fibroblast |
| Xiong 2017 J Am Heart Assoc | 2017 | Xiong S, Wang B, Lin S, Zhang H, Li Y, Wei X, Cui Y, Wei X, Lu Z, Gao P, Li L, Zhao Z, Liu D, Zhu Z (2017) Activation of transient receptor potential melastatin subtype 8 attenuates cold-induced hypertension through ameliorating vascular mitochondrial dysfunction. J Am Heart Assoc 6. pii: e005495. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Mouse | Endothelial;epithelial;mesothelial cell |
| Zholobenko 2017 PLOS ONE | 2017 | Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691. | LEAK OXPHOS ET ROUTINE | F N S NS ROX | Permeabilized cells Intact cells | Rat | Heart |
| JanssenDuijghuijsen 2017 Front Physiol | 2017 | JanssenDuijghuijsen LM, Grefte S, de Boer VCJ, Zeper L, van Dartel DAM, van der Stelt I, Bekkenkamp-Grovenstein M, van Norren K, Wichers HJ, Keijer J (2017) Mitochondrial ATP depletion disrupts Caco-2 monolayer integrity and internalizes Claudin 7. Front Physiol 8:794. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
| Chang 2017 J Biol Chem | 2017 | Chang JS, Ha K (2017) An unexpected role for the transcriptional coactivator isoform NT-PGC-1α in the regulation of mitochondrial respiration in brown adipocytes. J Biol Chem 292:9958-66. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Fat |
| Rodolphi 2017 Thesis | 2017 | Rodolphi MS (2017) Efeitos da nandrolona e da ceftriaxona na homeostasia glutamatérgica: uma busca por mecanismos interativos entre astrócitos e neurônios envolvidos no comportamento agressivo. Dissertation p58. | ROUTINE OXPHOS | S CIV ROX | Homogenate | Mouse | Nervous system |
| Wang 2017 J Am Heart Assoc | 2017 | Wang B, Xiong S, Lin S, Xia W, Li Q, Zhao Z, Wei X, Lu Z, Wei X, Gao P, Liu D, Zhu Z (2017) Enhanced mitochondrial transient receptor potential channel, canonical type 3-mediated calcium handling in the vasculature from hypertensive rats. J Am Heart Assoc 6. pii: e005812. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Rat | Endothelial;epithelial;mesothelial cell |
| Shimakawa 2017 Sci Rep | 2017 | Shimakawa G, Matsuda Y, Nakajima K, Tamoi M, Shigeoka S, Miyake C (2017) Diverse strategies of O2 usage for preventing photo-oxidative damage under CO2 limitation during algal photosynthesis. Sci Rep 7:41022. doi: 10.1038/srep41022 | ROUTINE | Eubacteria Plants Algae | |||
| Dechandt 2017 J Bioenerg Biomembr | 2017 | Dechandt CRP, Zuccolotto-Dos-Reis FH, Teodoro BG, Fernandes AMAP, Eberlin MN, Kettelhut IC, Curti C, Alberici LC (2017) Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr 49:399-411. | LEAK ROUTINE ET | F N ROX | Permeabilized cells Intact cells | Rat | Liver |
| Ortega 2017 Biol Reprod | 2017 | Ortega MS, Wohlgemuth S, Tribulo P, Siqueira LG, Null DJ, Cole JB, Da Silva MV, Hansen PJ (2017) A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows. Biol Reprod 96:652-63. | LEAK ROUTINE ET | ROX | Bovines | Blood cells | |
| Comelli 2017 J Bioenerg Biomembr | 2017 | Comelli M, Pretis I, Buso A, Mavelli I (2017) Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status. J Bioenerg Biomembr 50:33-52. | LEAK ROUTINE OXPHOS ET | N Gp CIV NS ROX | Intact cells Permeabilized cells | Human | Nervous system |
| Shuvo 2017 Can J Microbiol | 2017 | Shuvo SR, Kovaltchouk U, Zubaer A, Kumar A, Summers WAT, Donald LJ, Hausner G, Court DA (2017) Functional characterization of an N-terminally-truncated mitochondrial porin expressed in Neurospora crassa. Can J Microbiol 17:1-9. | ROUTINE | Isolated mitochondria | Fungi | ||
| Alves 2017 Free Radic Biol Med | 2017 | Alves de Souza CE, Alves de Souza HM, Stipp MC, Corso CR, Galindo CM, Cardoso CR, Dittrich RL, de Souza Ramos EA, Klassen G, Carlos RM, Correia Cadena SMS, Acco A (2017) Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol Med 110:228-39. | LEAK ROUTINE | ROX | Rat | ||
| Westerlund 2017 Pediatr Res | 2017 | Westerlund E, Marelsson SE, Ehinger JK, Sjövall F, Morota S, Åsander Frostner E, Oldfors A, Darin N, Lundgren J, Hansson MJ, Fellman V, Elmér E (2017) Oxygen consumption in platelets as an adjunct diagnostic method for pediatric mitochondrial disease. Pediatr Res 83:455-65. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Platelet Blood cells |
| Djordjevic 2017 Neuroscience | 2017 | Djordjevic J, Thomson E, Chowdhury SR, Snow WM, Perez C, Wong TP, Fernyhough P, Albensi BC (2017) Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease. Neuroscience 361:81-92. | ROUTINE OXPHOS ET | N S ROX | Isolated mitochondria | Mouse | Nervous system |
| Li 2017 Oxid Med Cell Longev | 2017 | Li CJ, Chen PK, Sun LY, Pang CY (2017) Enhancement of mitochondrial transfer by antioxidants in human mesenchymal stem cells. Oxid Med Cell Longev 2017:8510805. | ET LEAK ROUTINE | ROX | Intact cells | Human | Fat |
| Yang 2017 Cell Death Dis | 2017 | Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS (2017) Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death Dis 8:e2587. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Saccharomyces cerevisiae Human | Lymphocyte |
| Boutant 2017 EMBO J | 2017 | Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C (2017) Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-58. | ROUTINE LEAK OXPHOS ET | ROX N S NS | Intact cells Homogenate Isolated mitochondria | Mouse | Fat Fibroblast |
| Rodrigues-Silva 2017 J Neurooncol | 2017 | Rodrigues-Silva E, Siqueira-Santos ES, Ruas JS, Ignarro RS, Figueira TR, Rogério F, Castilho RF (2017) Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity. 10.1007/s11060-017-2482-0 | LEAK ROUTINE OXPHOS ET | N ROX | Permeabilized cells Isolated mitochondria Intact cells | Rat | Nervous system |
| Michalak 2017 Oxid Med Cell Longev | 2017 | Michalak S, Florczak-Wyspiańska J, Rybacka-Mossakowska J, Ambrosius W, Osztynowicz K, Baszczuk A, Kozubski W, Wysocka E (2017) Mitochondrial respiration in intact peripheral blood mononuclear cells and sirtuin 3 activity in patients with movement disorders. Oxid Med Cell Longev 2017:9703574. | LEAK ROUTINE ET | ROX | Intact cells | Blood cells | |
| Xu 2017 J Hum Genet | 2017 | Xu B, Li X, Du M, Zhou C, Fang H, Lyu J, Yang Y (2017) Novel mutation of ND4 gene identified by targeted next-generation sequencing in patient with Leigh syndrome. J Hum Genet 62:291-7. | LEAK ROUTINE | Intact cells | Human | Blood cells Platelet | |
| Cunha-de 2017 Thesis | 2017 | Cunha-de Padua MM (2017) Mecanismos citotóxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanádio em células de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivência de células de adenocarcinoma de cólon humano (LS174T). Doctoral Thesis p160. | LEAK ROUTINE OXPHOS ET | N NS ROX | Intact cells Permeabilized cells | Human | Liver Other cell lines |
| Nogueira 2017 Free Radic Biol Med | 2017 | Nogueira NP, Saraiva FMS, Oliveira MP, Mendonca APM, Inacio JDF, Almeida-Amaral EE, Menna-Barreto RF, Laranja GAT, Lopes Torres EJ, Oliveira MF, Paes MC (2017) Heme modulates Trypanosoma cruzi bioenergetics inducing mitochondrial ROS production. Free Radic Biol Med 108:183-91. | LEAK ROUTINE OXPHOS ET | S | Intact organism Permeabilized cells | Protists | |
| Greenall 2017 Oncogenesis | 2017 | Greenall SA, Lim YC, Mitchell CB, Ensbey KS, Stringer BW, Wilding AL, O'Neill GM, McDonald KL, Gough DJ, Day BW, Johns TG (2017) Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma. Oncogenesis 6:e336. | ROUTINE | Intact cells | Human | Nervous system | |
| Tegelberg 2017 Orphanet J Rare Dis | 2017 | Tegelberg S, Tomašić N, Kallijärvi J, Purhonen J, Elmér E, Lindberg E, Nord DG, Soller M, Lesko N, Wedell A, Bruhn H, Freyer C, Stranneheim H, Wibom R, Nennesmo I, Wredenberg A, Eklund EA, Fellman V (2017) Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model. Orphanet J Rare Dis 12:73. | LEAK ROUTINE OXPHOS ET | N NS ROX S | Permeabilized cells | Human Mouse | Blood cells Platelet |
| MiPNet21.14 Reference sample HRR | 2016-10-19 | | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Intact cells Permeabilized cells | Human | HEK |
| MiPNet21.12 Comparison mt respiration media | 2016-10-18 | | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | HEK |
| MiPNet08.09 CellRespiration | 2016-08-11 | | LEAK ROUTINE ET | Intact cells | Human | Blood cells Lymphocyte | |
| MiPNet10.04 CellRespiration | 2016-08-08 | | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Blood cells |
| Vevera 2016 Physiol Res | 2016 | Vevera J, Fišar Z, Nekovářová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeš K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88. | LEAK ROUTINE OXPHOS ET | N S NS Other combinations ROX | Intact cells Permeabilized cells | Human Rat | Blood cells Platelet |
| Frey 2016 Biochim Biophys Acta | 2016 | Frey S, Geffroy G, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Amati-Bonneau P, Chevrollier A, Barth M, Henrion D, Lenaers G, Bonneau D, Reynier P, Procaccio V (2016) The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model. Biochim Biophys Acta 1863:284-91. | ROUTINE LEAK ET | N S NS | Permeabilized cells Intact cells | Human | Nervous system |
| Chabot 2016 J Fish Biol | 2016 | Chabot D, McKenzie DJ, Craig JF (2016) Metabolic rate in fishes: definitions, methods and significance for conservation physiology. https://doi.org/10.1111/jfb.12873. | ROUTINE | Fishes | |||
| Gdynia 2016 Nat Commun | 2016 | Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairbäurl H, Kamiński MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W (2016) The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun 7:10764. | ROUTINE | ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
| Fonseca-Berzal 2016 Parasitology | 2016 | Fonseca-Berzal C, DA Silva CF, Menna-Barreto RF, Batista MM, Escario JA, Arán VJ, Gómez-Barrio A, Soeiro Mde N (2016) Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes. Parasitology 143:1469-78. | ROUTINE | ROX | Intact organism | Protists | |
| Liu 2016 Apoptosis | 2016 | Liu X, Gao RW, Li M, Si CF, He YP, Wang M, Yang Y, Zheng QY, Wang CY (2016) The ROS derived mitochondrial respiration not from NADPH oxidase plays key role in Celastrol against angiotensin II-mediated HepG2 cell proliferation. Apoptosis 21:1315-26. | ROUTINE | Intact cells | Human | Liver Other cell lines | |
| Drehmer 2016 Stem Cell Res | 2016 | Drehmer DL, de Aguiar AM, Brandt AP, Petiz L, Cadena SM, Rebelatto CK, Brofman PR, Filipak Neto F, Dallagiovanna B, Abud AP (2016) Metabolic switches during the first steps of adipogenic stem cells differentiation. Stem Cell Res 17:413-421. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fat Stem cells |
| Cacabelos 2016 Acta Neuropathol Commun | 2016 | Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J (2016) Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathol Commun 4:3. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized tissue Intact cells | Mouse | Nervous system Other cell lines |
| Salvi 2016 Oxid Med Cell Longev | 2016 | Salvi A, Patki G, Khan E, Asghar M, Salim S (2016) Protective effect of tempol on buthionine sulfoximine (BSO)-induced mitochondrial impairment in hippocampal derived HT22 cells. Oxid Med Cell Longev 2016:5059043. | ROUTINE | Intact cells | Mouse | Nervous system Other cell lines | |
| Dutra 2016 Acta Trop | 2016 | Dutra FL, Oliveira MM, Santos RS, Silva WS, Alviano DS, Vieira DP, Lopes AH (2016) Effects of linalool and eugenol on the survival of Leishmania (L.) infantum chagasi within macrophages. Acta Trop 164:69-76. | ROUTINE | ROX | Intact organism Intact cells | Protists | |
| Birkenmeier 2016 Int J Cancer | 2016 | Birkenmeier Katrin, Droese Stefan, Wittig Ilka, Winkelmann Ria, Kaefer Viktoria, Doering Claudia, Hartmann Sylvia, Wenz Tina, Reichert Andreas S, Brandt Ulrich, Hansmann Martin‐Leo (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines HeLa Macrophage-derived |
| Alvarez-Mora 2016 Mol Neurobiol | 2016 | Alvarez-Mora MI, Rodriguez-Revenga L, Madrigal I, Guitart-Mampel M, Garrabou G, Milà M (2016) Impaired mitochondrial function and dynamics in the pathogenesis of FXTAS. Mol Neurobiol 54:6896-902. | ROUTINE | N S NS | Intact cells | Human | Fibroblast |
| Zelenka 2016 Oxid Med Cell Longev | 2016 | Zelenka J, Dvořák A, Alán L, Zadinová M, Haluzík M, Vítek L (2016) Hyperbilirubinemia protects against aging-associated inflammation and metabolic deterioration. Oxid Med Cell Longev ID 6190609:10p. | ROUTINE | Intact cells Isolated mitochondria | Rat | Liver Kidney Fibroblast | |
| Tsai 2016 Sci Rep | 2016 | Tsai HH, Chang SC, Chou CH, Weng TP, Hsu CC, Wang JS (2016) Exercise training alleviates hypoxia-induced mitochondrial dysfunction in the lymphocytes of sedentary males. Sci Rep 6:35170. | LEAK ROUTINE OXPHOS ET | F N S NS Other combinations ROX | Permeabilized cells Intact cells | Human | Lymphocyte Blood cells |
| Schaefer 2016 PLOS ONE | 2016 | Schaefer PM, von Einem B, Walther P, Calzia E, von Arnim CA (2016) Metabolic characterization of intact cells reveals intracellular amyloid beta but not its precursor protein to reduce mitochondrial respiration. PLOS ONE 11:e0168157. | LEAK ROUTINE ET | CIV ROX | Intact cells | Human Mouse | Nervous system HEK |
| Castellano-Gonzalez 2016 Oncotarget | 2016 | Castellano-González G, Pichaud N, Ballard JW, Bessede A, Marcal H, Guillemin GJ (2016) Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes. Oncotarget 7:7426-40 | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
| Strecker 2016 Biochim Biophys Acta | 2016 | Strecker V, Kadeer Z, Heidler J, Cruciat CM, Angerer H, Giese H, Pfeiffer K, Stuart RA, Wittig I (2016) Supercomplex-associated Cox26 protein binds to cytochrome c oxidase. Biochim Biophys Acta 1863:1643-52. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
| Sheremet 2016 Biochemistry (Moscow) | 2016 | Sheremet NL, Nevinitsyna TA, Zhorzholadze NV, Ronzina IA, Itkis YS, Krylova TD, Tsygankova PG, Malakhova VA, Zakharova EY, Tokarchuk AV, Panteleeva AA, Karger EM, Lyamzaev KG, Avetisov SE (2016) Previously unclassified mutation of mtDNA m.3472T>C: evidence of pathogenicity in Leber’s hereditary optic neuropathy. Biochemistry (Moscow) BM16-078. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast Platelet |
| Boeck 2016 Mitochondrion | 2016 | Boeck C, Koenig AM, Schury K, Geiger ML, Karabatsiakis A, Wilker S, Waller C, Gündel H, Fegert JM, Calzia E, Kolassa IT (2016) Inflammation in adult women with a history of child maltreatment: The involvement of mitochondrial alterations and oxidative stress. Mitochondrion 30:197-207. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
| Torres 2016 Redox Biol | 2016 | Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72. | LEAK ROUTINE OXPHOS ET | N S ROX | Homogenate Intact cells | Human Mouse | Nervous system Liver Endothelial;epithelial;mesothelial cell Fibroblast |
| Xiong 2016 Hypertension | 2016 | Xiong S, Wang P, Ma L, Gao P, Gong L, Li L, Li Q, Sun F, Zhou X, He H, Chen J, Yan Z, Liu D, Zhu Z (2016) Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
| Raturi 2016 J Cell Biol | 2016 | Raturi A, Gutiérrez T, Ortiz-Sandoval C, Ruangkittisakul A, Herrera-Cruz MS, Rockley JP, Gesson K, Ourdev D, Lou PH, Lucchinetti E, Tahbaz N, Zaugg M, Baksh S, Ballanyi K, Simmen T (2016) TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux. J Cell Biol 214:433-44. | LEAK ET ROUTINE | Permeabilized cells Intact cells | Mouse Human | HeLa Other cell lines | |
| Larsen 2016 FASEB J | 2016 | Larsen FJ, Schiffer TA, Ørtenblad N, Zinner C, Morales-Alamo D, Willis SJ, Calbet JA, Holmberg HC, Boushel R (2016) High-intensity sprint training inhibits mitochondrial respiration through aconitase inactivation. FASEB J 30:417-27. | LEAK ROUTINE OXPHOS | N NS | Permeabilized cells Isolated mitochondria Intact cells | Human | Skeletal muscle |
| Schinagl 2016 PLoS One | 2016 | Schinagl CW, Vrabl P, Burgstaller W (2016) Adapting high-resolution respirometry to glucose-limited steady state mycelium of the filamentous fungus Penicillium ochrochloron: method development and standardisation. PLoS One 11:e0146878. | ROUTINE ET | Intact cells | Fungi | ||
| Yao 2016 Biochem Biophys Res Commun | 2016 | Yao K, Zhang WW, Yao L, Yang S, Nie W, Huang F (2016) Carvedilol promotes mitochondrial biogenesis by regulating the PGC-1/TFAM pathway in human umbilical vein endothelial cells (HUVECs). Biochem Biophys Res Commun 470:961-6. | ROUTINE | Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC | |
| Camacho-Pereira 2016 Cell Metab | 2016 | Camacho-Pereira J, Tarragó MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39. | LEAK ROUTINE OXPHOS ET | S ROX | Isolated mitochondria Intact cells | Human Mouse | Liver Lung;gill Other cell lines |
| Brandt 2016 Chem Biol Interact | 2016 | Brandt AP, Gozzi GJ, Pires Ado R, Martinez GR, Dos Santos Canuto AV, Echevarria A, Di Pietro A, Cadena SM (2016) Impairment of oxidative phosphorylation increases the toxicity of SYD-1 on hepatocarcinoma cells (HepG2). Chem Biol Interact 256:154-60. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver Other cell lines |
| Mesquita 2016 Thesis | 2016 | Mesquita Rodrigues C (2016) Efeito da depleção de ferro sobre Leishmania (Viannia) braziliensisuma análise ultraestrutural, proteômica e interação com matrizes de colágeno sintéticas. Doctoral Dissertation p210. | ROUTINE | ROX | Intact cells | Protists | |
| Bueno 2016 Thesis | 2016 | Bueno e Silva MM (2016) Alterações mitocondriais e reprogramação metabólica em células de glioblastoma após tratamento com temozolomida. Dissertation p71. | LEAK ROUTINE ET | Intact cells | Human | Nervous system Other cell lines | |
| Chakraborty 2016 Pancreatology | 2016 | Chakraborty M, Hickey AJ, Petrov MS, Macdonald JR, Thompson N, Newby L, Sim D, Windsor JA, Phillips AR (2016) Mitochondrial dysfunction in peripheral blood mononuclear cells in early experimental and clinical acute pancreatitis. Pancreatology 16:739-47. | LEAK OXPHOS ROUTINE ET | N Gp CIV NS ROX S | Permeabilized cells | Human Rat | Blood cells |
| Rohlenova 2016 Antioxid Redox Signal | 2016 | Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alisadeh E, Yan B, Nguyen M, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong L, Neuzil J (2016) Selective disruption of respiratory supercomplexes as a new strategy to suppress Her2high breast cancer. Antioxid Redox Signal 26:84-103. | LEAK ROUTINE ET | N S Other combinations | Permeabilized cells Homogenate | Human Mouse | Liver Genital Other cell lines |
| ... further results | |||||||
Abstracts: ROUTINE
Sort in ascending/descending order by a click on one of the small symbols in squares below.
| Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
|---|---|---|---|---|---|---|---|
| Gnaiger 2022 ESCI Bari | 2022 |  | LEAK ROUTINE ET | ROX | Intact cells | Human | Fibroblast |
| Magri 2022 Abstract Bioblast | 2022 | 8.5. «5 min»   | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Nervous system |
| Donnelly 2022 Abstract Bioblast | 2022 | 2.1. «10+5»  »MitoFit Preprint« | ROUTINE | ||||
| Wolf 2022 Abstract Bioblast | 2022 | 5.4. «10+5»  »Bioenergetics Communications« | ROUTINE | Intact cells | Human | Liver Other cell lines | |
| Gnaiger 2022 Abstract Bioblast-PB | 2022 | P03. »MitoFit Preprint« | ROUTINE | Intact cells | Algae | ||
| Porter 2022 Abstract Bioblast | 2022 | 6.3. «10+5»  »MitoFit Preprint« | LEAK ROUTINE ET | S ROX | Permeabilized cells | Human | |
| Hatokova 2019 MiPschool Coimbra | 2019 |  | LEAK ROUTINE ET | Intact cells | Human | Neuroblastoma | |
| Evinova 2019 MiPschool Coimbra | 2019 | | LEAK ROUTINE ET | N | Intact cells | Human | Neuroblastoma |
| Abdel-Rahman 2019 MiP2019 | 2019 | | ROUTINE OXPHOS | N NS | Intact cells | Human | Platelet |
| Pavlovic 2019 MiP2019 | 2019 |  | ROUTINE OXPHOS | N S | Intact cells | Mouse | Skeletal muscle |
| Cardoso 2019 MiP2019 | 2019 |  | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
| Bastos Sant'Anna Silva 2019 Life Sciences Meeting 2019 Innsbruck AT | 2019 | Cellular succinate transport and mitochondrial respiratory function in prostate cancer. | ROUTINE | S ROX | Intact cells | Human | Genital |
| Evinova 2018 MiP2018 | 2018 | | LEAK ROUTINE ET | Intact cells | Human | Other cell lines Neuroblastoma | |
| Garcia-Souza 2018 Life Sciences Meeting 2018 Innsbruck AT | 2018 | A respirometric cell viability test for peripheral-blood mononuclear cells and platelets. | LEAK ROUTINE ET | S | Intact cells | Human | Blood cells Platelet |
| Liu 2018 Atherosclerosis Suppl | 2018 | Liu D (2018) Enhanced Trpc3-mediated mitochondrial respiratory dysfunction by inhibition of mitochondria-hexokinase in monocytes from hypertension rats. Atherosclerosis Suppl. | ROUTINE OXPHOS ET | N NS | Intact cells | Rat | Blood cells |
| Chang 2018 Life Sciences Meeting 2018 Innsbruck AT | 2018 | pH dependence of mitochondrial respiration and H2O2 production in oral cancer cells – a pilot study. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells | Human | HEK Kidney |
| Gnaiger 2018 AussieMit | 2018 | Komlodi Timea, Sobotka Ondrej, Doerrier Carolina, Gnaiger Erich (2018) Mitochondrial H2O2 production is low under tissue normoxia but high at in-vitro air-level oxygen pressure - comparison of LEAK and OXPHOS states. AussieMit 2018 Melbourne AU. | LEAK ROUTINE OXPHOS | NS | Isolated mitochondria Intact cells | Mouse Saccharomyces cerevisiae | Heart Nervous system |
| Bastos Sant'Anna Silva 2018 TRANSMIT Bertinoro di Romagna IT | 2018 | Cellular succinate transport and mitochondrial respiratory function in prostate cancer. | ROUTINE LEAK OXPHOS ET | S ROX | Permeabilized cells Intact cells | Human | HEK Genital |
| Doerrier 2018 ESCI2018 | 2018 |  | LEAK ROUTINE OXPHOS ET | F N S Gp ROX CIV | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria | Human Mouse | Heart Skeletal muscle Nervous system Blood cells HEK |
| Bastos Sant'Anna Silva 2018 MiPschool Tromso C4 | 2018 |  | LEAK ROUTINE OXPHOS ET | S ROX | Intact cells | Human | Genital |
| Bastos Sant'Anna Silva 2018 Life Sciences Meeting 2018 Innsbruck AT | 2018 | Effect of cell-permeable succinate and malonate prodrugs on mitochondrial respiration in prostate cancer cells. | ROUTINE | Permeabilized cells Intact cells | Kidney Other cell lines HEK | ||
| Doerrier 2018 EBEC2018 | 2018 | | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Heart Nervous system Blood cells HEK Platelet |
| Garipi 2018 MiPschool Tromso E2 | 2018 | Phenotyping mitochondrial metabolism in Barrett’s metaplasia-dysplasia-adenocarcinoma sequence: respiratory capacity, extracelular proton flux and ROS production | LEAK ROUTINE OXPHOS ET | CIV NS ROX | Permeabilized cells Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
| Han 2018 MiP2018 | 2018 | | LEAK ROUTINE ET | Human | Kidney HEK | ||
| McMaster 2018 Am J Obstet Gynecol | 2018 | Preeclampsia is associated with placental mitochondrial dysfunction. | LEAK ROUTINE OXPHOS ET | N | Isolated mitochondria | Human | |
| Krylova 2017 MiPschool Obergurgl | 2017 |  | LEAK ROUTINE ET | N S | Intact cells Permeabilized cells | Endothelial;epithelial;mesothelial cell Fibroblast | |
| Nogueras 2017 MiPschool Obergurgl | 2017 |  | LEAK ROUTINE ET | ROX | Intact cells | Blood cells | |
| Irving 2017 MiP2017 | 2017 |  | LEAK ROUTINE OXPHOS ET | N NS ROX | Blood cells | ||
| Cizmarova 2017 MiP2017 | 2017 |  | LEAK ROUTINE ET | Intact cells | Human | Blood cells | |
| Gnaiger 2017 MiPschool A1 | 2017 |  | LEAK ROUTINE OXPHOS ET | ROX | Intact cells Permeabilized cells Permeabilized tissue Isolated mitochondria | ||
| Hellgren 2017 MiPschool Obergurgl | 2017 |  | LEAK ROUTINE ET | N | Homogenate | Mouse | Heart |
| Hartmann 2017 Abstract MITOEAGLE Barcelona | 2017 |  | LEAK ROUTINE ET | Intact cells | Human Pig | Blood cells | |
| Iyer 2017 MiP2017 | 2017 |  | LEAK ROUTINE | Human | Fibroblast | ||
| Doerrier 2017 MiPschool C2 | 2017 | | LEAK ROUTINE OXPHOS ET | F N S Gp CIV | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Heart Nervous system HEK |
| Garcia-Souza 2017 MiPschool Obergurgl | 2017 |  | ROUTINE ET | S CIV ROX | Intact cells Permeabilized cells | Human | Blood cells Platelet |
| Michalak 2017 Abstract MITOEAGLE Barcelona | 2017 | | LEAK ROUTINE OXPHOS ET | ROX | Intact cells | Human | Blood cells |
| Chang 2017 FASEB J | 2017 | Effects of cycling exercise on mitochondrial function and efficacy of peripheral blood mononuclear cells under hypoxic condition in sedentary men. | ROUTINE | N | Permeabilized cells Intact cells | Blood cells | |
| Michalak 2017 MiP2017 | 2017 | | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Siewiera 2017 MiPschool Obergurgl | 2017 |  | LEAK ROUTINE ET | Intact cells | Rat | Blood cells Platelet | |
| Siewiera 2017 Abstract MITOEAGLE Barcelona | 2017 | | ROUTINE ET | N | Intact cells | Human | Blood cells Platelet |
| Lin 2017 FASEB J | 2017 | Mitochondrial respiration is fiber-type specific in skeletal muscles. | LEAK ROUTINE | N NS | Permeabilized tissue | Rat | Skeletal muscle |
| Rybacka-Mossakowska 2017 MiP2017 | 2017 | | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
| Doerrier 2017 Abstract MitoEAGLE Barcelona | 2017 | | LEAK ROUTINE OXPHOS ET | F N S Gp CIV | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Heart Nervous system HEK |
| MitoFit Open Seminar 2017-07-14 | 2017 | Investigating the role of mitochondria in healthy and psychopathological aging. | LEAK ROUTINE ET | Intact cells | Human | Blood cells | |
| Calabria 2017 Abstract MITOEAGLE Barcelona | 2017 | | ROUTINE ET | Human | Blood cells | ||
| Garcia-Souza 2017 MiP2017 | 2017 | | ROUTINE ET | Human | Blood cells Platelet | ||
| Cizmarova 2017 Abstract MITOEAGLE Barcelona | 2017 | | ROUTINE ET | Intact cells | Human | Blood cells Platelet | |
| Sumbalova 2016b Abstract MitoFit Science Camp 2016 | 2016 | Human blood cells: isolation and HRR. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Intact cells | Human | Blood cells Lymphocyte Platelet |
| Gnaiger 2016 Abstract SFRR Australasia 2016 | 2016 | Facts and artefacts in measurements of H2O2 production under hypoxia. | ROUTINE | Intact cells | Saccharomyces cerevisiae | ||
| Weber 2016 Abstract Mito Xmas Meeting Innsbruck | 2016 | Loss of PTEN in prostate cancer cells leads to a switch to succinate-mediated mitochondrial respiration associated with increased expression of NaDC3 and HIF-1alpha. | ROUTINE | N NS | Permeabilized cells Intact cells | Human Mouse | Genital |
| Volani 2016 Abstract Mito Xmas Meeting Innsbruck | 2016 | Effects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo. | LEAK ROUTINE OXPHOS ET | N S | Homogenate | Mouse | Liver |
| Lamberti 2016 Abstract MitoFit Science Camp 2016 | 2016 | Development of a reference sample for HRR. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Human | Kidney HEK | |
| Doerrier 2016 Abstract MitoFit Science Camp 2016 | 2016 | Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria | Human Mouse | Heart Blood cells HEK Platelet |
| Van Dyk 2015 Abstract MiPschool Cape Town 2015 | 2015 | Optimization of selected cell lines for use on the Seahorse extracellular flux analyzer. | LEAK ROUTINE ET | N ROX | Isolated mitochondria | Human | Other cell lines Fibroblast |
| Karabatsiakis 2015 Abstract MiP2015 | 2015 | Mitochondrial respiration of peripheral blood mononuclear cells in patients with borderline personality disorder. | LEAK ROUTINE OXPHOS ET | ROX | Human | Blood cells | |
| Nuskova 2015 Abstract MiPschool London 2015 | 2015 | Insufficient energy provision or increased oxidative stress – what matters more in ATP synthase deficiencies? | ROUTINE OXPHOS | Human | HEK | ||
| Smenes 2015 Abstract IOC100 | 2015 | Smenes BT, Baekkerud FH, Hassel E, Wohlwend M, Slagsvold KH, Rognmo O, Wahba A (2015) Mitochondrial function in patients exercising prior to coronary surgery – A single blinded randomized controlled trial. Mitochondr Physiol Network 20.01. | LEAK ROUTINE ET | N S | Human | Skeletal muscle | |
| Rohlena 2015 Abstract MiP2015 | 2015 | Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation. | ROUTINE OXPHOS ET | S ROX | Permeabilized cells Isolated mitochondria | Human | Other cell lines |
| Dyrstad 2015 Abstract MiPschool London 2015 | 2015 | Activation of epithelial to mesenchymal transition (EMT) regulates stemness and metabolic reprogramming in mammary epithelial cells. | LEAK ROUTINE ET | N ROX | Human | Endothelial;epithelial;mesothelial cell Other cell lines | |
| Gnaiger 2015 Abstract MiPschool Cape Town 2015 | 2015 | The functional design of the electron transfer system (ETS) and mitochondrial respiratory control. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria | ||
| Volani 2015 Abstract IOC106 | 2015 | Volani C, Haschka D, Demetz E, Doerrier C, Gnaiger E, Weiss G (2015) Determination of mitochondrial respiration in peripheral blood mononuclear cells. Mitochondr Physiol Network 20.10. | ROUTINE OXPHOS ET | N S | Homogenate Intact cells | Human Mouse | Heart Liver Blood cells Lymphocyte |
| Rutkai 2015 Abstract MiPschool Greenville 2015 | 2015 | Sex-differences in mitochondrial respiration is mediated by nitric oxide in rat cerebral arteries. | LEAK ROUTINE ET | Rat | Endothelial;epithelial;mesothelial cell | ||
| Laner 2015 Abstract MiPschool Cape Town 2015 | 2015 | The Oroboros Oxygraph-2k for high-resolution respirometry and O2k-Fluorometry: a new quality in OXPHOS analysis. | LEAK ROUTINE OXPHOS ET | N S NS | Isolated mitochondria Intact cells | Mouse Saccharomyces cerevisiae | Heart |
| Hoppel 2015 Abstract MiP2015 | 2015 | Effects of ultramarathon performance on mitochondrial respiration in human platelets. | ROUTINE OXPHOS ET | N S NS | Permeabilized cells | Human | Blood cells Platelet |
| Gnaiger 2015 Abstract MiPschool Cape Town 2015 II | 2015 | On coupling control of mitochondrial respiration. What is wrong with the RCR? | LEAK ROUTINE OXPHOS ET | N S ROX | |||
| Gnaiger 2015 Abstract MiP2015 | 2015 | Mitochondrial function of cyropreserved HEK 293T cells: development of a reference sample for high-resolution respirometry. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Intact cells | Human | HEK |
| Mussulini 2015 Abstract MiPschool London | 2015 | Changes of brain substrates preference and metabolism during seizure induced by pentylenetetrazole in adult zebrafish. | ROUTINE ET | N S | Intact organ | Zebrafish | Nervous system |
| Alberici 2014 Abstract MiP2014 | 2014 | Effects of long-chain acyl-CoA synthetase 6 knockdown in primary skeletal muscle cells metabolism. | LEAK ROUTINE ET | Intact cells | Rat | Skeletal muscle | |
| Felser 2014 Abstract MiP2014 | 2014 | Assessing mitochondrial dysfunction in fibroblast cells – a comparison between O2k and multiwell respirometry. | ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell HeLa Fibroblast |
| Nagy 2014 Abstract MiP2014 | 2014 | Investigation of the energy metabolism of microglial cells. | ROUTINE ET | Intact cells | Human | Nervous system | |
| Widlund 2014 Abstract MiP2014 | 2014 | Resveratrol as a double edged sword on mitochondrial function. | ROUTINE | Intact cells | HeLa | ||
| Laner 2014 Abstract MiP2014 | 2014 | Cytochrome c flux control factor as a quality criterion in respiratory OXPHOS analysis in canine permeabilized fibers. | LEAK ROUTINE OXPHOS ET | N NS | Permeabilized tissue | Dog | Skeletal muscle |
| Eggimann 2014 Abstract MiP2014 | 2014 | Adaptation to nutrient availability in human fibroblasts with mitochondrial dysfunction: the role of sirtuins. | ROUTINE | Intact cells | Human | Fibroblast | |
| Karabatsiakis 2014 Abstract IOC96 | 2014 | Karabatsiakis A (2014) Consequences of depression on respiratory activity in peripheral blood mononuclear cells. Mitochondr Physiol Network 19.11. | LEAK ROUTINE ET | Intact cells | Human | Blood cells Lymphocyte | |
| El-Bacha 2014 Abstract MiP2014 | 2014 | Cytotoxicity of grape pomace extract (Vitis vinifera L.) from Brazilian wine industry in human hepatocarcinoma HepG2 cells. | LEAK ROUTINE ET | Intact cells | Human | Liver | |
| Oliveira HC 2013 Abstract MiP2013 | 2013 | Oliveira HC, Dorighello GG, Rovani JC, Raposo HF, Paim BA, Vercesi AE (2013) Intermittent fasting improves oxidative stress but not metabolic disturbances and atherosclerosis in hypercholesterolemic mice. Mitochondr Physiol Network 18.08. | ROUTINE | N | Intact organism Homogenate Isolated mitochondria | Mouse | Liver |
| Hendricks 2013 Abstract MiP2013 | 2013 | Hendricks E, Nathan BP, Menze MA (2013) Bioenergetics of permeabilized and intact nerve cell terminals from ApoE deficient and wild type mice. Mitochondr Physiol Network 18.08. | LEAK ROUTINE OXPHOS ET | N S NS | Intact cells Permeabilized cells Isolated mitochondria | Mouse | Nervous system |
| Zelenka J 2013 Abstract MiP2013 | 2013 | Zelenka J, Alan L, Jezek P(2013) Response of cancer cells to mitochondrial DNA damage. Mitochondr Physiol Network 18.08. | ROUTINE ET | Other cell lines | |||
| Oliveira MF 2013 Abstract MiP2013 | 2013 | Oliveira MF (2013) Comparative mitochondrial physiology in blood feeding insect vectors and parasites. Mitochondr Physiol Network 18.08. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV ROX | Intact organism Intact organ Permeabilized cells Permeabilized tissue Homogenate Intact cells | Human Drosophila Hexapods Other invertebrates | Skeletal muscle Neuroblastoma |
| Klamt 2013 Abstract IOC79 | 2013 | Klamt F (2013) Differences in basal mitochondrial respiratory parameters and reactive species generation between the cholinergic, dopaminergic and tumoral phenotypes of SH-SY5Y human neuroblastoma cell line. Mitochondr Physiol Network 18.07. | ROUTINE | Intact cells | Human | Neuroblastoma | |
| Camacho-Pereira 2013 Abstract IOC75 | 2013 | Camacho-Pereira J (2013) CD38 as a regulator of mitochondrial function. Mitochondr Physiol Network 18.03. | LEAK ROUTINE OXPHOS ET | N S NS | Intact cells Permeabilized cells Isolated mitochondria | Mouse | Liver HEK Macrophage-derived |
| Galina 2013 Abstract MiP2013 | 2013 | Galina A, Messeder DJM, Camacho-Pereira J, Pereira da Silva AP, Rodrigues-Ferreira C (2013) Effects of antitumor alkylating agent 3-bromopyruvate on energy transducing pathways in hepatoma HepG2, liver mitochondria and SERCA: Is there any role for mitochondrial hexokinase activity? Mitochondr Physiol Network 18.08. | LEAK ROUTINE OXPHOS ET | N S | Permeabilized cells Isolated mitochondria Enzyme Intact cells | Rat | Skeletal muscle Nervous system Liver Other cell lines |
| Rodrigues 2013 Abstract MiP2013 | 2013 | Rodrigues MF, Amoedo ND, Rumjanek FD (2013) Studies of bioenergetics alterations in breast cancer lines induced by histone desacetylase inhibitors. Mitochondr Physiol Network 18.08. | LEAK ROUTINE ET | ROX | Intact cells | Genital | |
| Amoedo 2013 Abstract MiP2013 | 2013 | Amoêdo ND, Rodrigues MF, Pereira S, Melo F, Jasiulionis M, Galina A, Rumjanek FD(2013) Comparative biochemistry of tumorigenesis: role of mitochondria in the metastatic process. Mitochondr Physiol Network 18.08. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Enzyme Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
| Wieckowski 2013 Abstract MiP2013 | 2013 | Wieckowski MR, Karkucinska-Wieckowska A, Wojtala A, Lebiedzinska M, Pronicki M, Duszynski J (2013) Mitochondrial bioenergetic parameters, reactive oxygen species production and the status of antioxidant defense system can be used to differentiate mitochondrial defects studied in the fibroblasts from patients with various mitochondrial disorders. Mitochondr Physiol Network 18.08. | ROUTINE | CIV NS | Intact cells | Human Mouse | Fibroblast |
| Sonkar 2013 Abstract MiP2013 | 2013 | Sonkar VK, Dash D, Kulkarn PP (2013) Platelets, amyloid beta and mitochondrial respiration. Mitochondr Physiol Network 18.08. | ROUTINE | Intact cells | Human | Blood cells | |
| Wojtala 2013 Abstract MiP2013 | 2013 | Wojtala A, Karkucinska-Wieckowska A, Lebiedzinska M, Duszynski J, Wieckowski MR(2013) Comparative studies of reactive oxygen species production and the level of antioxidant defense system in the fibroblasts derived from patients with defined mitochondrial disorders. Mitochondr Physiol Network 18.08. | ROUTINE | Intact cells | Human | Fibroblast | |
| Hickey 2013 Abstract MiP2013 | 2013 | Hickey AJ, Iftikar FI, MacDonald J, Baker D (2013) Mitochondria in a changing climate? The role of mitochondrial in hyperthermic heart failure in different fish species. Mitochondr Physiol Network 18.08. | LEAK ROUTINE OXPHOS ET | N S CIV NS | Permeabilized tissue | Other mammals Fishes | Heart |
| Menze 2013 Abstract MiP2013 | 2013 | Menze MA, Marunde MA, Samarajeewa DA, Anderson J, Li S, Hand SC (2013) Group1 LEA protein ameliorates inhibition of mitochondrial respiration in Drosophila melanogaster Kc167 cells and isolated mitochondria. Mitochondr Physiol Network 18.08. | LEAK ROUTINE OXPHOS | N | Intact organism Intact cells Permeabilized cells Isolated mitochondria Enzyme | Drosophila Artemia Crustaceans Hexapods | Other cell lines CHO HEK Macrophage-derived |
| Petit 2013 Abstract MiP2013 | 2013 | Petit PX (2013) The cardiolipin defect linked to a tafazzin mutation in Barth syndrome disturbs mitochondrial metabolism, alters apoptosis and autophagic fluxes but does not affect cell cycle progression. Mitochondr Physiol Network 18.08. | ROUTINE | Intact cells | Human | Blood cells Other cell lines HeLa | |
| Wright 2013 Abstract MiP2013 | 2013 | Wright L, Rizzuto R (2013) Calcium regulation of metabolism in adipocytes. Mitochondr Physiol Network 18.08. | ROUTINE | Intact cells | Mouse | Fat Other cell lines | |
| Jezek 2013 Abstract MiP2013 | 2013 | Ježek P, Ježek J, Zelenka J, Dlasková A, Jabůrek M (2013) Antioxidant synergy of mitochondrial uncoupling protein UCP2 and phospholipase iPLA2γ. Mitochondr Physiol Network 18.08. | LEAK ROUTINE OXPHOS ET | N S ROX | Isolated mitochondria Intact cells | Mouse | Lung;gill Islet cell;pancreas;thymus |
| Bouillaud 2013 Abstract MiP2013 | 2013 | Bouillaud F, Andriamihaja M, Mimoun S, Ransy C, Chaumontet C, Blachier F (2013) Adaptation of mitochondria in colonocytes to hydrogen sulfide exposure. Mitochondr Physiol Network 18.18. | ROUTINE | Other combinations | Intact cells | Other cell lines | |
| Garcia-Souza 2013 Abstract IOC80 | 2013 | Garcia-Souza LF (2013) Thrombin trigger mitochondrial functional remodeling in human platelets. Mitochondr Physiol Network 18.09. | LEAK ROUTINE ET | Intact cells | Human | Blood cells | |
| Zelenka 2013 Abstract MiP2013 | 2013 | Zelenka J, Smolkova K, Dvorak A, Vitek L, Jezek P (2013) Reverse carboxylation glutaminolysis in breast cancer cells. Mitochondr Physiol Network 18.08. | ROUTINE | Intact cells | Human | Other cell lines HeLa | |
| Watala 2012 Abstract Bioblast | 2012 | Watala C, Przygodzki T, Siewiera K, Kassassir H, Talar M, Labieniec-Watala M (2012) Oxygen consumption in resting and activated blood platelets: platelet mitochondria and cyclooxygenases as compounding targets for high-resolution respirometry. Mitochondr Physiol Network 17.12. | ROUTINE ET | NS ROX | Isolated mitochondria Enzyme Intact cells | Human Rat | Endothelial;epithelial;mesothelial cell Blood cells Platelet |
| Stoeger 2012 Abstract Bioblast | 2012 | Stoeger H, Fontana-Ayoub M, Eigentler A, Gnaiger E (2012) Cell respiration with yeast as a model. Mitochondr Physiol Network 17.12. | ROUTINE | Intact cells | Saccharomyces cerevisiae Fungi | ||
| Towheed 2012 Abstract IOC72 | 2012 | Towheed A (2012) Elucidating pathogenesis of ATP synthase dysfunction in a Drosophila model of mitochondrial encephalomyopathy. Mitochondr Physiol Network 17.13. | LEAK ROUTINE OXPHOS ET | N S NS | Intact organism Permeabilized tissue | Drosophila Hexapods | |
| Amoedo 2012 Abstract Bioblast | 2012 | Amoedo ND, Rodrigues MF, Pereira SAS, Melo FH, Jasiulionis MG, Galina A, Rumjanek FD (2012) Mitochondrial function and bioenergetics during malignant transformation and metastasis. Mitochondr Physiol Network 17.12. | LEAK ROUTINE OXPHOS ET | S | Intact cells | Mouse | Other cell lines |
| Albertini 2012 Abstract Bioblast | 2012 | Albertini E, Koziel R, Duerr A, Neuhaus M, Jansen-Duerr P (2012) Cystathionine beta synthase modulates senescence of human endothelial cells. Mitochondr Physiol Network 17.12. | LEAK ROUTINE ET | Intact cells | Endothelial;epithelial;mesothelial cell HUVEC | ||
| Mark 2012 Abstract Bioblast | 2012 | Mark FC, Strobel A, Poertner HO (2012) Ocean warming and acidification – when fish mitochondria turn sour. Mitochondr Physiol Network 17.12. | LEAK ROUTINE OXPHOS | N S CIV NS | Permeabilized tissue Isolated mitochondria | Fishes | Heart Liver |
| Acuna-Castroviejo 2012 Abstract Bioblast | 2012 | Acuna-Castroviejo D (2012) Melatonin and the quality of life: the melatonin-mitochondrion connection. Mitochondr Physiol Network 17.12. | ROUTINE OXPHOS | N S NS | Intact organism Isolated mitochondria Intact cells | Mouse Rat | Heart Skeletal muscle Nervous system Liver |
| Rodrigues 2012 Abstract IOC72 | 2012 | Rodrigues MF, Amoedo ND, Rumjanek FD (2012) Studies of bioenergetics alterations in breast cancer lines induced by sodium butyrate. Mitochondr Physiol Network 17.13. | LEAK ROUTINE ET | ||||
| Silva MiP 2011 | 2011 | Silva da Costa L, Pereira da Silva AP, Da Poian AT, El-Bacha T (2011) Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis Virus: Implications to viral replication and neuronal death. MiP2011. | ROUTINE | Intact cells | Neuroblastoma | ||
| Itkis 2010 Abstract IOC60 | 2010 | Itkis YS (2010) Respirometry application in Leigh disease diagnostic and treatment. MiPNet15.10. | ROUTINE | Intact cells | Human | Fibroblast |
MitoPedia concepts:
Respiratory state,
Recommended
MitoPedia methods:
Respirometry
MitoPedia topics:
EAGLE
