Difference between revisions of "Xtreme Everest 2"
From Bioblast
Line 4: | Line 4: | ||
[[File:O2k-Network.png|left|100px|link=O2k-Network|O2k-Network]] | [[File:O2k-Network.png|left|100px|link=O2k-Network|O2k-Network]] | ||
<big>'''Xtreme Everest 2'''</big> - '''two O2k-Network Labs collaborate in the expedition Xtreme Everest 2 (2013)''' | :::: <big>'''Xtreme Everest 2'''</big> - '''two O2k-Network Labs collaborate in the expedition Xtreme Everest 2 (2013)''' | ||
* [[UK Cambridge Murray AJ]]: [[Murray AJ|Andrew Murray]], [[Horscroft JA |James Horscroft]], [[Kotwica AO|Alex Kotwica]] | ::::* [[UK Cambridge Murray AJ]]: [[Murray AJ|Andrew Murray]], [[Horscroft JA |James Horscroft]], [[Kotwica AO|Alex Kotwica]] | ||
* [[AT Innsbruck MitoCom]]: [[Gnaiger E|Erich Gnaiger]], [[Laner V|Verena Laner]] | ::::* [[AT Innsbruck MitoCom]]: [[Gnaiger E|Erich Gnaiger]], [[Laner V|Verena Laner]] | ||
Line 15: | Line 15: | ||
High-resolution respirometry in two labs: | :::: High-resolution respirometry in two labs: | ||
* '''Kathmandu (KTM)- 1,400 m:''' two O2k (March 03 to 15) | ::::* '''Kathmandu (KTM)- 1,400 m:''' two O2k (March 03 to 15) | ||
* '''Everest Base Camp (EBC) - 5,364 m:''' three O2k (March 14 to May) | ::::* '''Everest Base Camp (EBC) - 5,364 m:''' three O2k (March 14 to May) | ||
: OROBOROS INSTRUMENTS with a Power-O2k approach (5 O2k) in the Xtreme Everest 2 expedition. OXPHOS analysis under hypoxia and high-altitude acclimation of muscle mitochondria in Sherpas and Caucasians. | :::: OROBOROS INSTRUMENTS with a Power-O2k approach (5 O2k) in the Xtreme Everest 2 expedition. OXPHOS analysis under hypoxia and high-altitude acclimation of muscle mitochondria in Sherpas and Caucasians. | ||
::::» General information: http://www.xtreme-everest.co.uk | |||
== Everest Base Camp - A Power-O2k Study of Mitochondrial Function == | == Everest Base Camp - A Power-O2k Study of Mitochondrial Function == | ||
=== Everest Base Camp Lab === | === Everest Base Camp Lab === | ||
[[Gnaiger_E| Erich Gnaiger]] (Innsbruck, AT) at Everest Base Camp (5,364 m) where acclimation to high altitude was studied using three O2k (March to May 2013). | :::: [[Gnaiger_E| Erich Gnaiger]] (Innsbruck, AT) at Everest Base Camp (5,364 m) where acclimation to high altitude was studied using three O2k (March to May 2013). | ||
Line 36: | Line 37: | ||
=== Kathmandu Lab === | === Kathmandu Lab === | ||
In Kathmandu (Nepal) at low altitude (1,400 m), [[UK_Cambridge_Murray_AJ| Andrew Murray]] (Cambridge, UK) operated [[Horscroft_2012_Abstract_IOC72| high-resolution respirometry on human musle biopsies]] with assistance by [[Laner_V| Verena Laner]] (Innsbruck, AT). | :::: In Kathmandu (Nepal) at low altitude (1,400 m), [[UK_Cambridge_Murray_AJ| Andrew Murray]] (Cambridge, UK) operated [[Horscroft_2012_Abstract_IOC72| high-resolution respirometry on human musle biopsies]] with assistance by [[Laner_V| Verena Laner]] (Innsbruck, AT). | ||
The participants from Innsbruck are supported by the K-Regio project [[MitoCom_O2k-Fluorometer| MitoCom Tyrol]], D. Swarovski Research Laboratory (Medical University of Innsbruck), and OROBOROS INSTRUMENTS. | :::: The participants from Innsbruck are supported by the K-Regio project [[MitoCom_O2k-Fluorometer| MitoCom Tyrol]], D. Swarovski Research Laboratory (Medical University of Innsbruck), and OROBOROS INSTRUMENTS. | ||
<gallery mode=packed widths="231px" heights="198px" perrow=5> | <gallery mode=packed widths="231px" heights="198px" perrow=5> | ||
Line 67: | Line 68: | ||
<big>''' | == Everest Base Camp (EBC) - 5,364 m == | ||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Ebc1.jpg | |||
File:Ebc2.jpg | |||
File:Erich EBC.jpg | |||
File:Ebc4.jpg | |||
File:Ebc5.jpg | |||
File:Ebc6.jpg | |||
File:Ebc7.jpg | |||
File:Ebc8.jpg | |||
File:Ebc9.jpg | |||
File:Ebc10.jpg | |||
File:Ebc11.jpg | |||
File:Ebc12.jpg | |||
File:Ebc13.jpg | |||
File:Ebc14.jpg | |||
File:Ebc16.jpg | |||
File:Ebc15.jpg | |||
File:Ebc18.jpg | |||
File:Ebc19.jpg | |||
File:Ebc20.jpg | |||
File:Ebc21.jpg | |||
File:Ebc22.jpg | |||
File:Ebc23.jpg | |||
File:Ebc24.jpg | |||
File:Ebc25.jpg | |||
File:Ebc26.jpg | |||
File:Ebc27.jpg | |||
File:Ebc28.jpg | |||
File:Ebc29.jpg | |||
File:Ebc30.jpg | |||
File:Ebc31.jpg | |||
File:Ebc32.jpg | |||
File:Ebc33.jpg | |||
File:Ebc34.jpg | |||
File:Ebc35.jpg | |||
File:Ebc36.jpg | |||
File:Ebc37.jpg | |||
</gallery> | |||
== Kathmandu Lab - 1,400 m == | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Ktm1.jpg | |||
File:Ktm2.jpg | |||
File:Ktm3.jpg | |||
File:Ktm4.jpg | |||
File:Ktm5.jpg | |||
File:Ktm6.jpg | |||
File:Ktm7.jpg | |||
File:Ktm8.jpg | |||
File:Ktm9.jpg | |||
File:Ktm10.jpg | |||
File:Ktm11.jpg | |||
File:Ktm12.jpg | |||
File:Ktm13.jpg | |||
File:Ktm14.jpg | |||
File:Ktm15.jpg | |||
File:Ktm16.jpg | |||
File:Ktm17.jpg | |||
File:Ktm18.jpg | |||
File:Ktm19.jpg | |||
File:Ktm20.jpg | |||
</gallery> | |||
== Namche - 3,440 m == | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Namche1.jpg | |||
File:Namche2.jpg | |||
File:Namche3.jpg | |||
File:Namche4.jpg | |||
File:Namche5.jpg | |||
File:Impr1.jpg | |||
File:Namche7.jpg | |||
File:Namche8.jpg | |||
File:Namche9.jpg | |||
File:Namche10.jpg | |||
File:Namche11.jpg | |||
File:Namche12.jpg | |||
File:Namche13.jpg | |||
File:Namche14.jpg | |||
</gallery> | |||
== Khunde - 3,840 m == | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Khunde1.jpg | |||
File:Khunde2.jpg | |||
File:Khunde3.jpg | |||
File:Khunde4.jpg | |||
File:Khunde5.jpg | |||
File:Khunde6.jpg | |||
File:Khunde7.jpg | |||
File:Khunde8.jpg | |||
File:Khunde9.jpg | |||
File:Khunde10.jpg | |||
File:Khunde11.jpg | |||
File:Khunde12.jpg | |||
File:Khunde13.jpg | |||
File:Khunde14.jpg | |||
File:Khunde15.jpg | |||
File:Khunde16.jpg | |||
</gallery> | |||
== Khumjung - 3,750 m == | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Khumjung1.jpg | |||
File:Khumjung2.jpg | |||
File:Khumjung3.jpg | |||
File:Khumjung4.jpg | |||
</gallery> | |||
== Khumbu to EBC == | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Kumbu1.jpg | |||
File:Kumbu2.jpg | |||
File:Kumbu3.jpg | |||
File:Kumbu4.jpg | |||
File:Kumbu5.jpg | |||
File:Kumbu6.jpg | |||
File:Kumbu7.jpg | |||
File:Kumbu8.jpg | |||
File:Kumbu9.jpg | |||
File:Kumbu10.jpg | |||
File:Kumbu11.jpg | |||
File:Kumbu12.jpg | |||
File:Kumbu13.jpg | |||
File:Kumbu14.jpg | |||
File:Kumbu15.jpg | |||
File:Kumbu16.jpg | |||
File:Kumbu18.jpg | |||
File:Kumbu19.jpg | |||
File:Kumbu20.jpg | |||
File:Kumbu21.jpg | |||
File:Kumbu22.jpg | |||
File:Kumbu23.jpg | |||
File:Kumbu24.jpg | |||
File:Kumbu25.jpg | |||
File:Kumbu26.jpg | |||
File:Kumbu27.jpg | |||
File:Kumbu28.jpg | |||
File:Kumbu29.jpg | |||
File:Kumbu30.jpg | |||
File:Kumbu31.jpg | |||
File:Kumbu32.jpg | |||
File:Kumbu33.jpg | |||
File:Kumbu34.jpg | |||
</gallery> | |||
== The Mountain == | |||
:::: <big>'''Mount Everest - 8,848 m'''</big> | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Berge2.jpg | |||
File:Mt Everest2.jpg | |||
File:Mt Everest3.jpg | |||
File:Mt Everest4.jpg | |||
File:Mt Everest5.jpg | |||
File:Mt Everest6.jpg | |||
File:Mt Everest7.jpg | |||
File:Mt Everest8.jpg | |||
File:Mt Everest9.jpg | |||
File:Mt Everest10.jpg | |||
</gallery> | |||
:::: <big>'''Khumbu Glacier from Kala Pattar - 5,545 m'''</big> | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Mt Everest11.jpg | |||
File:Mt Everest12.jpg | |||
File:Mt Everest13.jpg | |||
</gallery> | |||
== People == | |||
:::: <big>'''Sherpas and Sherpanis in the Khumbu Valley'''</big> | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:People1.jpg | |||
File:People2.jpg | |||
File:People3.jpg | |||
File:People4.jpg | |||
File:People5.jpg | |||
File:People6.jpg | |||
File:People7.jpg | |||
File:People8.jpg | |||
File:People9.jpg | |||
File:People10.jpg | |||
File:People11.jpg | |||
File:People12.jpg | |||
File:People13.jpg | |||
File:People14.jpg | |||
</gallery> | |||
:::: <big>'''Kathmandu'''</big> | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:People15.jpg | |||
</gallery> | |||
== Yak et al == | |||
:::: <big>'''Yaks'''</big> | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Yaks1.jpg | |||
File:Yaks2.jpg | |||
File:Yaks3.jpg | |||
File:Yaks4.jpg | |||
File:Yaks5.jpg | |||
File:Yaks6.jpg | |||
File:Yaks7.jpg | |||
File:Yaks8.jpg | |||
File:Yaks9.jpg | |||
File:Yaks10.jpg | |||
</gallery> | |||
:::: <big>'''Musk deer and others'''</big> | |||
<gallery mode=packed widths="192px" heights="165px" perrow=5> | |||
File:Musk1.jpg | |||
File:Musk2.jpg | |||
File:Musk3.jpg | |||
File:Musk4.jpg | |||
</gallery> | |||
<small>''Photography: Erich Gnaiger''</small> | :::: <small>''Photography: Erich Gnaiger''</small> | ||
== Infos and Links == | == Infos and Links == | ||
* [http://www.xtreme-everest.co.uk Xtreme Everest 2] - the expedition website | ::::* [http://www.xtreme-everest.co.uk Xtreme Everest 2] - the expedition website | ||
* [http://www.xtreme-everest.co.uk/article.php?newsid=858| OROBOROS INSTRUMENTS - sponsor of Xtreme Everest 2] | ::::* [http://www.xtreme-everest.co.uk/article.php?newsid=858| OROBOROS INSTRUMENTS - sponsor of Xtreme Everest 2] | ||
* Sherpa (East men) migrated around 1530 to 1600 from the province Kham (Eastern Tibet) into the Khumbu area. About 90% of the Sherpa in Solu Khumbu trace back to this migration (Kai Gildhorn: Nepal. Mount Everest Trek). | ::::* Sherpa (East men) migrated around 1530 to 1600 from the province Kham (Eastern Tibet) into the Khumbu area. About 90% of the Sherpa in Solu Khumbu trace back to this migration (Kai Gildhorn: Nepal. Mount Everest Trek). | ||
* Michael Kodas (2008) High crimes. The fate of Everst in an age of greed. Hyperion, New York (German edition: Der Gipfel des Verbrechens. Die Everest-Mafia und ihre dreckigen Geschäfte. Malik, National Geographic). | ::::* Michael Kodas (2008) High crimes. The fate of Everst in an age of greed. Hyperion, New York (German edition: Der Gipfel des Verbrechens. Die Everest-Mafia und ihre dreckigen Geschäfte. Malik, National Geographic). | ||
== Track record == | == Track record == | ||
* 2013-03-01: The teams fly from London and Innsbruck/Munich to Kathmandu (KTM). | ::::* 2013-03-01: The teams fly from London and Innsbruck/Munich to Kathmandu (KTM). | ||
* 2013-03-02: Arrival in KTM, where the equipment is unpacked at Summit Hotel. | ::::* 2013-03-02: Arrival in KTM, where the equipment is unpacked at Summit Hotel. | ||
* 2013-03-03: The two O2k are set up in the general lab: Sensor service, sensor test, calibration, instrumental background. | ::::* 2013-03-03: The two O2k are set up in the general lab: Sensor service, sensor test, calibration, instrumental background. | ||
* 2013-03-04: Alex and James fly to Lucla to start the ascent towards Everest Base Camp (EBC). The first Sherpa volunteers come into the KTM lab. Another series of O2k performance tests. | ::::* 2013-03-04: Alex and James fly to Lucla to start the ascent towards Everest Base Camp (EBC). The first Sherpa volunteers come into the KTM lab. Another series of O2k performance tests. | ||
* 2013-03-05: Biopsies of two Sherpa volunteers were analyzed with two protocols in the O2k - a successful start of the first functional mitochondrial study in Sherpas. | ::::* 2013-03-05: Biopsies of two Sherpa volunteers were analyzed with two protocols in the O2k - a successful start of the first functional mitochondrial study in Sherpas. | ||
* 2013-03-06: The Sherpa biopsies are continued in the KTM lab. Erich flies to Lukla, to catch up with the EBC team. | ::::* 2013-03-06: The Sherpa biopsies are continued in the KTM lab. Erich flies to Lukla, to catch up with the EBC team. | ||
* 2013-03-07: Erich meets the EBC team at the Namche laboratory. | ::::* 2013-03-07: Erich meets the EBC team at the Namche laboratory. | ||
* 2013-03-11: Power cut interrupts second experiment on this day. The team gets a short debrief before the last day of experiments gets started. | ::::* 2013-03-11: Power cut interrupts second experiment on this day. The team gets a short debrief before the last day of experiments gets started. | ||
* 2013-03-12: Experiments finished today. Alltogether, 15 muscle biopsies were taken by Prof. David Howard. The KTM-team celebrates the successful run of experiments | ::::* 2013-03-12: Experiments finished today. Alltogether, 15 muscle biopsies were taken by Prof. David Howard. The KTM-team celebrates the successful run of experiments | ||
*2013-03-13: A last run of instrumental background for quality assurance of the data. | ::::* 2013-03-13: A last run of instrumental background for quality assurance of the data. |
Revision as of 04:19, 14 April 2016
Xtreme Everest 2
- Xtreme Everest 2 - two O2k-Network Labs collaborate in the expedition Xtreme Everest 2 (2013)
High-resolution respirometry at extremes
- High-resolution respirometry in two labs:
- Kathmandu (KTM)- 1,400 m: two O2k (March 03 to 15)
- Everest Base Camp (EBC) - 5,364 m: three O2k (March 14 to May)
- OROBOROS INSTRUMENTS with a Power-O2k approach (5 O2k) in the Xtreme Everest 2 expedition. OXPHOS analysis under hypoxia and high-altitude acclimation of muscle mitochondria in Sherpas and Caucasians.
- High-resolution respirometry in two labs:
- » General information: http://www.xtreme-everest.co.uk
Everest Base Camp - A Power-O2k Study of Mitochondrial Function
Everest Base Camp Lab
- Erich Gnaiger (Innsbruck, AT) at Everest Base Camp (5,364 m) where acclimation to high altitude was studied using three O2k (March to May 2013).
Kathmandu Lab
- In Kathmandu (Nepal) at low altitude (1,400 m), Andrew Murray (Cambridge, UK) operated high-resolution respirometry on human musle biopsies with assistance by Verena Laner (Innsbruck, AT).
- The participants from Innsbruck are supported by the K-Regio project MitoCom Tyrol, D. Swarovski Research Laboratory (Medical University of Innsbruck), and OROBOROS INSTRUMENTS.
Impressions from Kathmandu to Everest Base Camp
Everest Base Camp (EBC) - 5,364 m
Kathmandu Lab - 1,400 m
Namche - 3,440 m
Khunde - 3,840 m
Khumjung - 3,750 m
Khumbu to EBC
The Mountain
- Mount Everest - 8,848 m
- Khumbu Glacier from Kala Pattar - 5,545 m
People
- Sherpas and Sherpanis in the Khumbu Valley
- Kathmandu
Yak et al
- Yaks
- Musk deer and others
- Photography: Erich Gnaiger
Infos and Links
- Xtreme Everest 2 - the expedition website
- OROBOROS INSTRUMENTS - sponsor of Xtreme Everest 2
- Sherpa (East men) migrated around 1530 to 1600 from the province Kham (Eastern Tibet) into the Khumbu area. About 90% of the Sherpa in Solu Khumbu trace back to this migration (Kai Gildhorn: Nepal. Mount Everest Trek).
- Michael Kodas (2008) High crimes. The fate of Everst in an age of greed. Hyperion, New York (German edition: Der Gipfel des Verbrechens. Die Everest-Mafia und ihre dreckigen Geschäfte. Malik, National Geographic).
Track record
- 2013-03-01: The teams fly from London and Innsbruck/Munich to Kathmandu (KTM).
- 2013-03-02: Arrival in KTM, where the equipment is unpacked at Summit Hotel.
- 2013-03-03: The two O2k are set up in the general lab: Sensor service, sensor test, calibration, instrumental background.
- 2013-03-04: Alex and James fly to Lucla to start the ascent towards Everest Base Camp (EBC). The first Sherpa volunteers come into the KTM lab. Another series of O2k performance tests.
- 2013-03-05: Biopsies of two Sherpa volunteers were analyzed with two protocols in the O2k - a successful start of the first functional mitochondrial study in Sherpas.
- 2013-03-06: The Sherpa biopsies are continued in the KTM lab. Erich flies to Lukla, to catch up with the EBC team.
- 2013-03-07: Erich meets the EBC team at the Namche laboratory.
- 2013-03-11: Power cut interrupts second experiment on this day. The team gets a short debrief before the last day of experiments gets started.
- 2013-03-12: Experiments finished today. Alltogether, 15 muscle biopsies were taken by Prof. David Howard. The KTM-team celebrates the successful run of experiments
- 2013-03-13: A last run of instrumental background for quality assurance of the data.