Talk:Carboxyatractyloside

Sources of Cat

Chinopoulos C

I have used the Sigma Cat as well, but not for titration studies. It works perfectly at 1-2 µM concentrations, if you want to block completely all ANTs. The MW is 770.8.

The Sigma Cat originates from Atr extracted from Xanthicum sibericum. A carboxylation is a further chemical modification. The Merck Cat originates from Atr from Atractylis gummifera, which is identical to that from Xanthicum. A carboxylation is a further chemical modification. Because of this modification which is man-made, there may be different potencies. For titration studies (0-200 nM Cat), the one from Merck (Atractylis gummifera) is strongly recommended. - Christos (2012-04-19)

Chu MJJ

Unfortunately Merck does not sell the Cat from Atractylis gummifera anymore and currently only offers the Cat extracted from Xanthicum sibericum (as does Sigma). - Michael (2012-04-20)