Substrate control: Difference between revisions

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{{MitoPedia
#REDIRECT [[Electron-transfer-pathway state]]
|description=Substrate control with electron entry separately through [[Complex I]] (pyruvate+malate or glutamate+malate) or [[Complex II]] (succinate+rotenone) restricts [[ETS capacity]] and artificially enhances flux control upstream of the Q-cycle, providing diagnostic information on specific branches of the ETS.  Physiological combinations of Complex I+II substrates support maximum ETS and [[OXPHOS capacity|OXPHOS capacities]], due to the additive effect of multiple electron supply pathways converging at the [[Q-junction]].
|info=[[MiPNet12.12]]
|type=Respiration
}}
{{Labeling
|instruments=Chemicals; Media
|discipline=Mitochondrial Physiology
|topics=Respiration; OXPHOS; ETS Capacity
|enzymes=Complex I, Complex II; Succinate Dehydrogenase
}}

Latest revision as of 15:16, 2 June 2020

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