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• O2k-Publications: Inhibitor
  ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Inhibitor]] == O2k-Publications: Inhibitor - Abstracts ==
  1 KB (186 words) - 11:44, 11 November 2016
• Substrate-uncoupler-inhibitor titration
  |description=Mitochondrial '''Substrate-uncoupler-inhibitor titration''' ('''SUIT''') [[MitoPedia: SUIT |protocols]] are used with [[mi {{#ask:[[Additional label::Substrate-uncoupler-inhibitor titration]]
  3 KB (339 words) - 08:57, 27 May 2020
• Substrate-uncoupler-inhibitor-titration
  #REDIRECT [[Substrate-uncoupler-inhibitor titration]]
  53 bytes (3 words) - 22:41, 31 August 2015

Page text matches

• Phenylsuccinate
  |description='''Phenylsuccinate''' is a competitive inhibitor of succinate transport (20 mM). |type=Inhibitor
  227 bytes (24 words) - 15:56, 2 May 2014
• Bongkrekik acid
  |description='''Bongkrekik acid''' is a selective and potent inhibitor of the [[adenine nucleotide translocator]] (ANT). Bka binds to the matrix ( |type=Inhibitor PS
  366 bytes (47 words) - 20:51, 23 August 2015
• Hydroxycinnamate
  ...cription='''Hydroxycinnamate''' (alpha-cyano-4-hydroxycinnamic acid) is an inhibitor of the [[pyruvate carrier]] (0.65 mM). Above 10 mM [[pyruvate]], hydroxyci |type=Inhibitor ETS
  537 bytes (63 words) - 15:53, 2 May 2014
• N-ethylmaleimide
  |type=Inhibitor PS {{MitoPedia methods|type=Inhibitor PS
  409 bytes (52 words) - 12:58, 12 February 2021
• MitoPedia: Inhibitors
  »[[O2k-Publications: Inhibitor]] {{#ask:[[MitoPedia topic::Inhibitor]]
  210 bytes (21 words) - 16:18, 10 February 2015
• Hydroxylamine
  |description='''Hydroxylamine''' is an inhibitor of [[catalase]]. |mitopedia topic=Inhibitor
  2 KB (312 words) - 12:19, 21 April 2021
• Mersalyl
  ...iption='''Mersalyl''' (C₁₃H₁₇HgNO₆) is an inhibitor of the [[Pi symporter]]. |type=Inhibitor
  768 bytes (122 words) - 12:55, 12 February 2021
• Thenoyltrifluoroacetone
  |description='''Thenoyltrifluoroacetone''' TTFA is a noncompetitive inhibitor of CII binding on the quinone-binding (SDHC/SDHD). |mitopedia topic=Inhibitor
  332 bytes (37 words) - 23:25, 2 April 2023
• Amytal
  ...mobarbital; 5-Ethyl-5-isoamylbarbituric acid) is a barbiturate drug and an inhibitor of [[Complex I]]. |type=Inhibitor ETS
  920 bytes (127 words) - 11:53, 22 June 2021
• 2-mercaptoacetate
  ...of [[octanoylcarnitine]] oxidation. 2-mercaptoacetate has been used as an inhibitor of [[fatty acid oxidation]] ([[F-pathway control state]]). In permeabilized |mitopedia topic=Inhibitor
  723 bytes (84 words) - 17:08, 18 January 2022
• Substrate-uncoupler-inhibitor-titration
  #REDIRECT [[Substrate-uncoupler-inhibitor titration]]
  53 bytes (3 words) - 22:41, 31 August 2015
• Tartronic acid
  ...artronic acid (hydroxymalonic acid, C3H4O5; molecular weight 120.06) is an inhibitor of [[malic enzyme]]. |mitopedia topic=Inhibitor
  650 bytes (76 words) - 10:37, 11 September 2020
• Citreoviridin
  ...tor of the [[ATP synthase]] which, differently from the FO subunit binding inhibitor oligmycin, binds to the F1 subunit of the ATP synthase. |mitopedia topic=Inhibitor
  910 bytes (125 words) - 10:15, 11 September 2020
• Atractyloside
  |description='''Atractyloside''' is an inhibitor of the [[Adenine nucleotide translocator|adenine nucleotide translocator (A |type=Inhibitor PS
  1 KB (199 words) - 12:47, 12 February 2021
• O2k-Publications: Inhibitor
  ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Inhibitor]] == O2k-Publications: Inhibitor - Abstracts ==
  1 KB (186 words) - 11:44, 11 November 2016
• Oxalomalic acid
  |description='''Oxalomalic acid''' is an inhibitor of aconitase (and of cytoplasmic NADP-dependent isocitrate dehydrogenase). |mitopedia topic=Inhibitor
  680 bytes (89 words) - 11:18, 2 June 2016
• Dinitrochlorobenzene
  ...lorobenzene (1-chloro-2,4-dinitrobenzene)''' (DNCB) is a glutathione (GSH) inhibitor. ...cavenging H₂O₂. Additionally, [[auranofin]] (AF), an inhibitor of thioredoxin reductase (TrxR) can be used to quantified the contribution
  2 KB (217 words) - 10:20, 11 September 2020
• Kuznetsov 1997 Biochim Biophys Acta
  ...V, Winkler K, Kirches E, Lins H, Feistner H, Kunz WS (1997) Application of inhibitor titrations for the detection of oxidative phosphorylation defects in saponi ...of flux control was observed. We conclude, therefore, that application of inhibitor titrations and the quantitative description of the titration curve can be a
  2 KB (327 words) - 17:24, 16 January 2021
• Krishnathas 2017 Med Chem Comm
  ...henyl)ethyl]quinazoline-4,6-diamine as a novel, highly potent and specific inhibitor of mitochondrial complex I. Med Chem Comm 8:657-61. ...r results challenge the postulated primary mode-of-action of EVP4593 as an inhibitor of NF-κB pathway activation and/or store-operated calcium influx.
  2 KB (232 words) - 13:49, 4 June 2018
• Metabolic control variable
  ...kground to reference steady state (Y to Z). Alternatively, ''X'' may be an inhibitor of flux, absent in the reference state but present in the background state |mitopedia topic=Inhibitor, Substrate and metabolite, Uncoupler
  858 bytes (123 words) - 18:19, 10 November 2020
• Cyanide
  |description='''Cyanide''' (usually added as KCN) is a competitive inhibitor of [[Complex_IV| cytochcrome ''c'' oxidase (CIV)]]. Inhibition is reversed {{MitoPedia O2k and high-resolution respirometry|type=Inhibitor ETS
  3 KB (360 words) - 09:51, 10 June 2021
• Sun 2012 Front Mol Neurosci
  ...ylketone completely inhibited caspase activation, while treatment with the inhibitor of calpains- and papain-like cathepsins (2S,3S)-trans-epoxysuccinyl-leucyla
  2 KB (278 words) - 13:52, 29 July 2016
• Azide
  |description='''Sodium azide''' is an inhibitor of [[Complex IV]]/cytochrome ''c'' oxidase (CIV, COX, CcO). |type=Inhibitor ETS
  2 KB (337 words) - 17:28, 16 December 2021
• Belosludtsev 2018 Biochemistry (Mosc)
  ...s of dequalinium (≤10 μM), this swelling is inhibited by cyclosporin A, an inhibitor of the mitochondrial permeability transition pore. At the same time, at hig |topics=Inhibitor, Ion;substrate transport
  2 KB (282 words) - 09:04, 5 October 2018
• Hildyard 2003 Biochem J
  ...ily (MCF). Only mitochondria from the YIL006w deletion mutant exhibited no inhibitor-sensitive pyruvate transport, but otherwise behaved normally. YIL006w encod
  1 KB (138 words) - 17:17, 16 January 2021
• Degli Esposti 1998 Biochim Biophys Acta
  ...compounds and their potency is related to that of rotenone, the classical inhibitor of complex I. Among commercial products, particular attention is dedicated |keywords=NADH–ubiquinone reductase; Respiratory inhibitor; Ubiquinone
  1 KB (158 words) - 13:55, 12 March 2021
• Auranofin
  ...itochondria: Trx system. Additionally, [[dinitrochlorobenzene]] (DNCB), an inhibitor of glutathione (GSH) can be used to obtain the GSH contribution scavenging ...H, Kim GY, Moon SK, Cheong J, Kim WJ, Yoo YH, Choi YH (2017) Auranofin, an inhibitor of thioredoxin reductase, induces apoptosis in hepatocellular carcinoma Hep
  2 KB (282 words) - 10:11, 11 September 2020
• Strobilurin
  |mitopedia topic=Inhibitor
  498 bytes (64 words) - 02:46, 23 January 2023
• Mathiyazakan 2023 Antimicrob Agents Chemother
  ...cobacterium tuberculosis'' cytochrome ''bcc:aa''3 supercomplex and a novel inhibitor targeting subunit cytochrome ''c''I. Antimicrob Agents Chemother 67:e015312 ...ion via the cIcII head. The successful identification of a new cyt-bcc:aa3 inhibitor demonstrates the potential of a structure-mechanism-based approach for nove
  2 KB (335 words) - 18:10, 17 September 2023
• Becker 1999 Am J Physiol
  ...dase inhibitor diphenyleneiodonium (0.9 +/- 0.1). By contrast, the site IV inhibitor cyanide, as well as inhibitors of xanthine oxidase (allopurinol), nitric ox
  2 KB (242 words) - 17:49, 13 April 2022
• Stoner 1984 J Bioenerg Biomembr
  ...ill make the other more rate limiting and thus will decrease the amount of inhibitor of the other required for half-maximal inhibition. These two types of "coup
  3 KB (369 words) - 22:45, 16 February 2021
• Grefte 2015 Biochim Biophys Acta
  ...bited by Rot (10-100 nM), but not by piericidin A (PA; 100 nM), another CI inhibitor. At 100 nM, both Rot and PA fully blocked myoblast oxygen consumption. Knoc |topics=Inhibitor
  2 KB (244 words) - 10:43, 9 November 2016
• Razak 2018 RUMeS
  ...s measured using OROBOROS HRR Oxygraph-2k according to substrate-uncoupler-inhibitor titration (SUIT) protocol. ...d following the addition of complex I inhibitor (rotenone) and complex III inhibitor (antimycin A).
  2 KB (322 words) - 11:47, 8 April 2019
• Briston 2016 Sci Rep
  ...owney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in ...dependent of CypD inhibition. Here we identified a novel, CypD-independent inhibitor of the mPTP. The screening approach and compound described provides a workf
  2 KB (331 words) - 14:25, 21 September 2021
• Kunz 1993 FEBS Lett
  ...or EGTA, the inhibitor of Ca²⁺ transport Ruthenium red and the inhibitor of the myosin ATPase vanadate. The caffeine concentration dependency of res
  1 KB (185 words) - 11:00, 27 March 2018
• Qvit 2022 Pharmaceuticals (Basel)
  ...A, Ostberg NP, Campos JC, Ferreira JCB, Mochly-Rosen D (2022) A selective inhibitor of cardiac troponin I phosphorylation by delta protein kinase C (δPKC) as ...ylation of cTnI is critical in IR injury, and that a cTnI/δPKC interaction inhibitor should be considered as a therapeutic target to reduce cardiac injury after
  2 KB (280 words) - 18:55, 6 December 2022
• Kopitar-Jerala 2017 Abstract MITOEAGLE Barcelona
  ...nes in macrophages. It was reported that metformin, mitochondria complex I inhibitor, decreased production of the pro-form of the inflammatory cytokine IL-1β a Stefin B (cystatin B) is an endogenous cysteine cathepsin inhibitor, and the loss-of-function mutations in the stefin B gene were reported in p
  2 KB (289 words) - 08:17, 21 February 2020
• Gottfried 2013 PLoS One
  ..., diclofenac holds potential as a clinically applicable MYC and glycolysis inhibitor supporting established tumor therapies.
  3 KB (382 words) - 08:54, 21 February 2020
• Vanden Hoek 1998 J Biol Chem
  ...y myxothiazol, but not by diphenyleneiodonium or the nitric-oxide synthase inhibitor L-nitroarginine. We conclude that hypoxia increases mitochondrial superoxid
  2 KB (263 words) - 20:58, 11 April 2022
• Etomoxir
  ...(Eto; 2[6(4-chlorophenoxy)hexyl]oxirane-2-carboxylate) is an irreversible inhibitor of [[carnitine palmitoyltransferase I]] (CPT-I) on the outer face of the mi |mitopedia topic=Inhibitor
  1 KB (184 words) - 06:35, 20 April 2023
• Palmeira 2019 MiP2019
  ...tion of ischemia/reperfusion injury: effects of a soluble adenylyl cyclase inhibitor LRE1. ...a setting of rodent model of hepatic IR. Therefore, we tested LRE1 (a sAC inhibitor) administration before I/R.
  2 KB (344 words) - 16:01, 7 October 2019
• Lambertucci 2008 J Cell Physiol
  ...tion induced by PA was observed by treatment with diphenylene iodonium, an inhibitor of NADPH oxidase. The participation of this enzyme complex was confirmed th
  2 KB (278 words) - 23:16, 5 July 2021
• 3-Mercaptopropionic acid
  |mitopedia topic=Inhibitor
  521 bytes (61 words) - 08:41, 17 March 2023
• Triethyltin bromide
  |description=Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial [[ATP synthase]] [2] which is used to induce [[LEAK st |mitopedia topic=Inhibitor
  1 KB (195 words) - 10:37, 11 September 2020
• Teplova 2017 Toxicol Lett
  ...its capability of acting as both a protonophore and an unusual complex II inhibitor, which interferes with the mitochondrial respiration by blocking the electr |keywords=Complex II inhibitor, Mitochondria, Q(d)-binding site, Superoxide anion, Triclosan, Uncoupler
  2 KB (297 words) - 08:48, 27 June 2019
• Torres-Quesada 2022 Cancers (Basel)
  ...nveiled mitochondrial dysfunction upon exposure to the FDA-approved kinase inhibitor sunitinib. This seemingly context-dependent side effect of this drug highli ...cells, cell bioenergetics, cell culture media, cell proliferation, kinase inhibitor, mitochondrial function
  2 KB (314 words) - 15:16, 9 December 2022
• Kraft 2004 Thesis Universität Halle-Wittenberg - Germany
  ...cooling was without interruption. The newly established multiple substrate-inhibitor titration provides the possibility to measure complex I dependent functiona ...r technique, respirometry, mitochondria, mitochondrial function, substrate-inhibitor-titration, mitochondrial encephalomyopathy, shipment of samples
  2 KB (197 words) - 17:56, 7 November 2016
• Antal 2013 Planta
  ...of mitochondrial respiration, FCCP, a protonophore, nor propyl gallate, an inhibitor of the plastid terminal oxidase, induced such a strong effect like antimyci
  1 KB (216 words) - 15:00, 8 August 2023
• Hsu 2004 Biochemistry
  ...act=Human mitochondrial malic enzyme is a regulatory enzyme with ATP as an inhibitor. Structural studies reveal that the enzyme has two ATP-binding sites, one a |topics=ATP, Inhibitor
  1 KB (220 words) - 15:40, 1 August 2014
• Galina 2014 Int J Biochem Cell Biol
  |keywords=3-Bromopyruvate, Glycolytic inhibitor, Mitochondrial respiration inhibitor, Alkylation,Tumor cell metabolism
  2 KB (210 words) - 14:06, 12 June 2022

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