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  • ...es and new potential targets to reduce damage by reperfusion injury across a broad spectrum of tissues. #Piper HM, D. Garcña-Dorado D, Ovize M (1998) A fresh look at reperfusion injury. Cardiovasc Res 38:291-300.
    4 KB (528 words) - 10:24, 8 November 2016
  • ...Eric M, Tsakiridis Evangelia E, Lally James SV, Juracic Emma Sara, Tupling A Russell, Gerstein Hertzel C, Pare Guillaume, Tsakiridis Theodoros, Harper M ...f GDF15 to maintain energy expenditure during calorie restriction requires a GFRAL-β-adrenergic-dependent signalling axis that increases fatty acid oxi
    4 KB (571 words) - 11:07, 12 July 2023
  • ...(inhibitor of CI) prevents the accumulation of oxaloacetate (Oa) which is a strong competitive inhibitor of CII [1]. ...ared [2]. In addition, respiration and NADH redox state were measured with a prototype NextGen-O2k, which combines high-resolution respirometry with O2k
    5 KB (714 words) - 18:35, 10 January 2022
  • ...act as signaling and/or damaging molecules. Accumulating evidence suggests a mechanistic link between cellular and mitochondrial ROS signals and mitocho ...llocchio L, Soria-Gómez E, Matias I, Delamarre A, Metna-Laurent M, Cannich A, Hebert-Chatelain E, Mulle C, Ortega-Gutiérrez S, Martín-Fontecha M, Klug
    4 KB (594 words) - 16:32, 26 March 2018
  • |authors=Renshaw G, Hickey A, Devaux J ...e anoxia tolerant epaulette shark maintained mitochondrial efficiency with a low ROS release in response to oxygen limitation, including anoxia [4]. The
    6 KB (859 words) - 14:55, 23 January 2019
  • ...ically different. Especially, the cybrids harboring mtDNA haplogroup D had a significantly slower growth rate. These findings suggest that mitochondrial ...cals emerged as important factor for MetS as well as type 2 diabetes. With a novel cell based assays we found serum levels of mitochondria inhibitor act
    5 KB (755 words) - 17:37, 25 February 2020
  • ...[2]. In the present study, we used succinate with and without rotenone as a model for pathophysiological mitochondrial ROS-production. ...ously using Amplex Ultrared [3]. NAD(P)H autofluorescence was monitored in a prototype NextGen-O2k, which combines HRR with O2k-Spectrofluorometry. Step
    7 KB (948 words) - 18:37, 10 January 2022
  • :::# Tretter LA, Patocs A, Chinopoulos C (2016) Succinate, an intermediate in metabolism, signal tran ...Chouchani ET, Pell VR, Gaude E, Aksentijević D, Sundier SY, Robb EL, Logan A, Nadtochiy SM, Ord EN, Smith AC, Eyassu F, Shirley R, Hu CH, Dare AJ, James
    6 KB (912 words) - 18:51, 10 January 2022
  • ...the membrane, because of a high octanol/water distribution coefficient. As a result, SkQ1 concentration in the inner mitochondrial membrane can be 10<su ...and glaucoma. Again, SkQ1 proved to be much more efficient than thymolol, a non-targeted antioxidant.
    6 KB (934 words) - 09:07, 25 October 2017

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