Difference between revisions of "Salicylhydroxamic acid"
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{{MitoPedia | {{MitoPedia | ||
|abbr=SHAM | |abbr=SHAM | ||
|description='''Salicylhydroxamic acid''' (SHAM; synonym: 2-Hydroxybenzohydroxamic acid N,2-Dihydroxybenzamide) is an inhibitor of alternative oxidases (AOX). When AOX is blocked by SHAM, electrons are forced through the cytochrome pathway and through cytochrome IV, allowing observation of the operation of the cytochrome pathway without AOX activity. | |description='''Salicylhydroxamic acid''' (SHAM; synonym: 2-Hydroxybenzohydroxamic acid N,2-Dihydroxybenzamide) is an inhibitor of [[alternative oxidases]] (AOX). When AOX is blocked by SHAM, electrons are forced through the cytochrome pathway and through cytochrome IV, allowing observation of the operation of the cytochrome pathway without AOX activity. | ||
|info=[[Parrino_2000_JEB]] | |info=[[Parrino_2000_JEB]] | ||
}} | }} | ||
{{MitoPedia methods}} | |||
{{MitoPedia topics | {{MitoPedia topics | ||
|mitopedia topic=Inhibitor | |mitopedia topic=Inhibitor | ||
}} | }} | ||
== Application in [[HRR]] == | == Application in [[HRR]] == | ||
'''SHAM: Salicylhydroxamic acid''' (99%; HOC<sub>6</sub>H<sub>4</sub>CONHOH); Sigma S 607, 5 g, store at R.T.; FW = 153.14 | '''SHAM: Salicylhydroxamic acid''' (99%; HOC<sub>6</sub>H<sub>4</sub>CONHOH); Sigma S 607, 5 g, store at R.T.; FW = 153.14 |
Revision as of 22:54, 17 April 2014
Description
Salicylhydroxamic acid (SHAM; synonym: 2-Hydroxybenzohydroxamic acid N,2-Dihydroxybenzamide) is an inhibitor of alternative oxidases (AOX). When AOX is blocked by SHAM, electrons are forced through the cytochrome pathway and through cytochrome IV, allowing observation of the operation of the cytochrome pathway without AOX activity.
Abbreviation: SHAM
Reference: Parrino_2000_JEB
MitoPedia topics: Inhibitor
Application in HRR
SHAM: Salicylhydroxamic acid (99%; HOC6H4CONHOH); Sigma S 607, 5 g, store at R.T.; FW = 153.14