Difference between revisions of "SRot"
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|description='''S(Rot)''': [[Succinate]] supports electron flux through CII via flavin adenine dinucleotide (FADH2). After inhibition of CI by [[rotenone]], the NADH-linked dehydrogenases become inhibited by the redox shift from NAD+ to NADH (Fig. 4.1). Succinate dehydrogenase is activated by succinate and ATP, which explains in part the time-dependent increase of respiration in isolated mitochondria after addition of rotenone (first), succinate and ADP. | |description='''S(Rot)''': [[Succinate]] supports electron flux through CII via flavin adenine dinucleotide (FADH2). After inhibition of CI by [[rotenone]], the NADH-linked dehydrogenases become inhibited by the redox shift from NAD+ to NADH (Fig. 4.1). Succinate dehydrogenase is activated by succinate and ATP, which explains in part the time-dependent increase of respiration in isolated mitochondria after addition of rotenone (first), succinate and ADP. | ||
|info=[[Gnaiger 2014 MitoPathways |Gnaiger 2014 MitoPathways - Chapter 4.1] | |info=[[Gnaiger 2014 MitoPathways |Gnaiger 2014 MitoPathways - Chapter 4.1]] | ||
}} | }} | ||
{{MitoPedia methods}} | {{MitoPedia methods}} | ||
Revision as of 17:07, 22 January 2016
- high-resolution terminology - matching measurements at high-resolution
SRot
Description
S(Rot): Succinate supports electron flux through CII via flavin adenine dinucleotide (FADH2). After inhibition of CI by rotenone, the NADH-linked dehydrogenases become inhibited by the redox shift from NAD+ to NADH (Fig. 4.1). Succinate dehydrogenase is activated by succinate and ATP, which explains in part the time-dependent increase of respiration in isolated mitochondria after addition of rotenone (first), succinate and ADP.
Abbreviation: S(Rot)
Reference: Gnaiger 2014 MitoPathways - Chapter 4.1
MitoPedia topics: "Respiratory substrate-coupling state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory substrate-coupling state"Respiratory substrate-coupling state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
