Phosphocreatine: Difference between revisions
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|abbr= | |abbr=PCr | ||
|description='''Phosphocreatine'''is a high energy compound in the skeletal muscle of vertebrates and is present in 4 to 5 times the concentration of ATP. | |description='''Phosphocreatine'''is a high energy compound in the skeletal muscle of vertebrates and is present in 4 to 5 times the concentration of ATP. | ||
|info=[[Saks 2000 Acta Physiol Scand]] | |info=[[Saks 2000 Acta Physiol Scand]] | ||
Revision as of 10:29, 21 May 2012
- high-resolution terminology - matching measurements at high-resolution
Phosphocreatine
Description
Phosphocreatineis a high energy compound in the skeletal muscle of vertebrates and is present in 4 to 5 times the concentration of ATP.
Abbreviation: PCr
Reference: Saks 2000 Acta Physiol Scand
MitoPedia topics: Substrate and metabolite
The high-energy phosphate group of phosphocreatine is rapidly transferred to ADP by the action of creatine kinase and the following reaction occurrs:
- Phosphocreatine + ADP ↔ creatine + ATP
ATP formation is favored at the expense of phosphocreatine. This fact explains why the ATP concentration of muscle does not decline during a single contraction: the terminal phosphate group lost from ATP during the contraction is instantly replenished at the expence of phosphocreatine.
If the muscle is stimulated for longer periods in the absence of glycolysis or respiration, the phosphocreatine supply will eventually become depleted. Only then the ATP concentration will decline.
