Fatty acid oxidation pathway control state: Difference between revisions

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high-resolution terminology - matching measurements at high-resolution

Fatty acid oxidation pathway control state

Description

In the fatty acid oxidation or FAO-linked substrate state, one or several fatty acids are supplied to feed electrons into the F-junction through fatty acyl CoA dehydrogenase (reduced form FADH2), to electron transferring flavoprotein (CETF), and further through the Q-junction to Complex III (CIII). FAO not only depends on electron transfer through the F-junction (which is typically rate-limiting) but simultaneously generates NADH and thus depends on N-junction throughput. Hence FAO can be inhibited completely by inhibition of Complex I (CI). In addition and independent of this source of NADH, the type N substrate malate is required as a co-substrate for FAO in mt-preparations, since accumulation of AcetylCo inhibits FAO in the absence of malate. Malate is oxidized in a reaction catalyzed by malate dehydrogenase to oxaloacetate (yielding NADH), which then stimulates the entry of AcetylCo into the TCA cycle catalyzed by citrate synthase.

Abbreviation: FAO, F

Reference: Gnaiger 2014 MitoPathways

MitoPedia O2k and high-resolution respirometry: "SUIT state" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property. SUIT state"SUIT state" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property.

» O2k-Network discussion forum: fatty acids used in permeabilized fibre assays

» Fatty acid oxidation

FAO(L)

FAO_L

FAO(P)

FAO_P

FAO(E)

FAO_E

O2k-Publications: FAO

Sort in ascending/descending order by a click on one of the small symbols in squares below.
Default sorting: chronological. Empty fields appear first in ascending order.

O2k-Publications: FAO - Abstracts

Sort in ascending/descending order by a click on one of the small symbols in squares below.

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+::::» [[Talk:Fatty acid oxidation |O2k-Network discussion forum: fatty acids used in permeabilized fibre assays]]
+::::» [[Fatty acid oxidation]]
+== FAO(L) ==
+:::: FAO<sub>''L''</sub>
+== FAO(P) ==
+:::: FAO<sub>''P''</sub>
+== FAO(E) ==
+:::: FAO<sub>''E''</sub>
+[[Image:O2k-Publications.jpg|left|116px|link=O2k-Publications: Topics|O2k-Publications in the MiPMap]]
+== O2k-Publications: FAO ==
+ '''''Sort in ascending/descending order by a click on one of the small symbols in squares below'''''.
+ Default sorting: chronological. Empty fields appear first in ascending order.
+{{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Substrate states::FAO]]
+|?Was published in year=Year
+|?Has title=Reference
+|?Tissue and cell
+|?Cell line
+|?Mammal and model
+|?Nonmammal
+|format=broadtable
+|limit=5000
+|offset=0
+|sort=Was published in year
+|order=descending
+}}
+[[Image:O2k-Publications.png|left|115px|link=http://www.bioblast.at/index.php/O2k-Publications:    Topics|O2k-Publications in the MiPMap]]
+== O2k-Publications: FAO - Abstracts ==
+ '''''Sort in ascending/descending order by a click on one of the small symbols in squares below'''''.
+{{#ask:[[Category:Abstracts]] [[Instrument and method::Oxygraph-2k]] [[Substrate states::FAO]]
+|?Was submitted in year=Year
+|?Has title=Reference
+|?Tissue and cell
+|?Cell line
+|?Mammal and model
+|?Nonmammal
+|format=broadtable
+|limit=5000
+|offset=0
+|sort=Was submitted in year
+|order=descending
+}}