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...mitochondrial state 4). In following, the respiratory control ratio (RCR - state 3/state4) was calculated as an index of mitochondrial oxidative-phosphoryla |couplingstates=LEAK, OXPHOS

.... The effect of exercise and caloric balance on oxidative phosphorylation (OXPHOS). Abstract FEPS, Santiago de Compostela, Spain. Symposium: Advances in Agin ...at low mitochondrial density is an important mechanistic candidate in the state of mitochondrial fever.

...the adenine nucleotide translocase (ANT) inhibitor bongkrekic acid during state 4 respiration was similar in healthy and burned patients. In line with this |couplingstates=LEAK, OXPHOS

...ochondria as well as submitochondrial structures in the functional, intact state, a major advance in super-resolution studies of living organelles. ::::* OXPHOS consists of the electron transport chain (ETC) plus the ATP synthase.

...ximal uncoupled respiration or the electron transport system capacity (ETS state, FCCP-induced). The non-mitochondrial, residual oxygen consumption (ROX) wa Preliminary data showed a significant decrease in both CI and CII-dependent OXPHOS and ETS in adult but not in pediatric patients with acute leukemias and lym

...00-210 mV consistent with the physiologic transition from [[State 3]] to [[State 4]] of respiration. Extension of the metabolic flux control analysis to the |couplingstates=LEAK, OXPHOS

..., glutamate, and succinate) and ADP. Maximal uncoupled mitochondrial VO2 (State 4 respiration) was subsequently determined following the addition of oligom ...hy children (1.74±0.23 vs. 0.79±0.23 pmol/(mg*sec), P<0.05). In addition, state 4 respiration was 4-fold greater in severely burned children relative to he

...tent fasting results in tissue-specific changes in bioenergetics and redox state. PLoS One 10:e0120413. ...of IF on redox status are not. Here, we address the effects of IF on redox state markers in different tissues in order to uncover how changes in feeding fre

...3 SNPs can explain 31, 13, and 18% of the phenotypic variation in state 3, state 4, and P:O ratio, respectively. Most of the genes tagged by the SNPs are in |couplingstates=LEAK, OXPHOS

...t mutation of this cysteine which forms disulphide bridges in an oxidative state, apparently renders MFN2 more susceptible to alterations of the redox envir |couplingstates=LEAK, ROUTINE, OXPHOS, ET

...nd treated mice. The present work demonstrates that the physiopathological state of AH involves mitochondrial dysfunction in mouse cerebellum showing the lo |couplingstates=LEAK, OXPHOS

...of our study was to comparatively characterize oxidative phosphorylation (OXPHOS) in the atrophic and nonatrophic gastric corpus mucosa. Compared to the control group, the maximal capacity of OXPHOS in the atrophy group was almost twofold lower, the respiratory chain comple

...e the apparent biochemical mechanisms underlying glycolysis activation and OxPhos downregulation in HeLa-M cells.

...At higher concentrations (50-100 UM), these fatty acids decreased state 4, state 3 and uncoupled respiration, suggesting metabolic inhibition. Furthermore, |couplingstates=LEAK, OXPHOS, ET

...IU, ATP (5 µM to 10.0 mM) was titrated into the medium to establish steady state rates of oxygen consumption. Under these conditions, low rates of respirati |couplingstates=OXPHOS

|title=Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice ir ...on a causal link between altered white adipocyte mitochondria in the obese state and changes in glucose homeostasis. We here aimed to dissect whether altera

...ited the RET. The titration of ADP at saturating concentrations to reach [[OXPHOS]] allows us to harmonize this protocol with [[ SUIT-006 O2 mt D022]] for qu ...the measurements the O₂ concentration will be changed and each state will be measure at an O₂ concentration >100 µM and <50 µM.

...maximum level of ∆Ψm induced by succinate in synaptosomes in a depolarized state. Similarly, insulin decreased ROS production in neuronal cultures. In mitoc |couplingstates=LEAK, OXPHOS, ET

...atio (RCR). Ischemic rat and human liver samples consistently showed lower State-III respiration, ETC capacity and RCR, compared to normal perfused liver sa Consistent measurement of liver MF and detection of derangement in a disease state was successfully demonstrated using less than half the tissue from a single

...-[[ET capacity| ''E'']]) with NADH-linked substrates ([[PM-pathway control state|PM]] and PGM)''' ...may be relevant in the presence of [[glutamate-anaplerotic pathway control state]]. SUIT-012 can be extended with the CIV assay module.