P/E control ratio: Difference between revisions
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{{MitoPedia | {{MitoPedia | ||
|abbr=P/E | |abbr=P/E | ||
|description=The | |description=The OXPHOS control ratio or OXPHOS/ETS capacity decreases with limitation by the phosphorylation system. P/E increases from the lower boundary set by L/E (zero capacity of the phosphorylation system), to the upper limit of 1.0, when there is no limitation of P by the phosphorylation system or the proton backpressure (capacity of the phosphorylation system fully matches the ETS capacity; or if the system is fully uncoupled). It is important to separate the effect of ADP limitation from limitation by enzymatic capacity at saturating ADP concentration. | ||
|info=[[MiPNet12.15]], [[Gnaiger_2009_IJCBC]] | |info=[[MiPNet12.15]], [[Gnaiger_2009_IJCBC]], Pesta_2010_Protocols | ||
|type=Respiration | |type=Respiration | ||
}} | }} |
Revision as of 13:40, 15 September 2010
Description
The OXPHOS control ratio or OXPHOS/ETS capacity decreases with limitation by the phosphorylation system. P/E increases from the lower boundary set by L/E (zero capacity of the phosphorylation system), to the upper limit of 1.0, when there is no limitation of P by the phosphorylation system or the proton backpressure (capacity of the phosphorylation system fully matches the ETS capacity; or if the system is fully uncoupled). It is important to separate the effect of ADP limitation from limitation by enzymatic capacity at saturating ADP concentration.
Abbreviation: P/E
Reference: MiPNet12.15, Gnaiger_2009_IJCBC, Pesta_2010_Protocols
Labels:
Regulation: Respiration; OXPHOS; ETS Capacity"Respiration; OXPHOS; ETS Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.