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Bioblast alert 2020(10) - MitoEAGLE & BEC news: 2020-05-20

Bioenergetics Communications MitoEAGLE Consortium Communication: Mitochondrial physiology ― Published online: 2020-05-20.

Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1
» https://www.bioenergetics-communications.org/index.php/BEC2020.1_doi10.26124bec2020-0001.v1

SI Units SI units

One year ago, on World Metrology Day (2019-May-20) the redefinition of the SI units came into force. Science faced one of the largest overhauls in history of scientific units. How to commemorate this event of groundbreaking innovation better than with the online publication of Mitochondrial physiology and with the launch of an innovative journal — Bioenergetics Communications.

Bioblast alert 2020(09) - MitoEAGLE News: 2020-04-09

MitoEAGLE The MitoEAGLE whitepaper on ‘Mitochondrial respiratory states and rates’ is now ready for re-submission to Nature Metabolism. The full-length preprint with a total word count of 17,000 has been reduced to 3,000 words text plus figures and references, including all original sections.

Version 6 of the paper with all 620 coauthors is available here:

» www.mitoeagle.org/index.php/Gnaiger_2019_MitoFit_Preprint_Arch

Please contact us, if you are interested to see the shortened version of the manuscript.
If you intend to join as an additional coauthor, please send your comments, full institutional address and preferentially your ORCID iD to [email protected]


MitoEAGLE The July MitoEAGLE Summit and Training School (including the TRANSMIT workshop) have been postponed by the management committee. More information to follow.

» https://wiki.oroboros.at/index.php/MitoEAGLE_Summit_Obergurgl_2020

» https://wiki.oroboros.at/index.php/MiPschool_Obergurgl_2020



Bioblast alert 2020(08) - MitoFit Preprint Archives News: 2020-03-25

MitoFit pdf Vitamin D deficiency: a factor in COVID-19 progression severity and mortality? An urgent call for research

Brown RA, Sarkar A (2020) Vitamin D deficiency: a factor in COVID-19, progression, severity and mortality? – An urgent call for research. MitoFit Preprint Arch doi:10.26124/mitofit:200001.


Bioblast alert 2020(07): 2020-03-20

From MitoFit Preprint Archives to Nature Communications

O2k-Publications in the MiPMap High-resolution respirometry in human prostate cancer biopsies and mtDNA analyzed in samples recovered from the O2k-chamber

- from the O2k-Network »AT Innsbruck Oroboros« Schöpf Bernd, Weissensteiner Hansi, Schäfer Georg, Fazzini Federica, Charoentong Pornpimol, Naschberger Andreas, Rupp Bernhard, Fendt Liane, Bukur Valesca, Giese Irina, Sorn Patrick, Sant’Anna-Silva Ana Carolina, Iglesias-Gonzalez Javier, Sahin Ugur, Kronenberg Florian, Gnaiger Erich, Klocker Helmut (2020) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. Nat Commun 2020-03-20 [Epub ahead of print]. - »Bioblast link«


MitoFit pdf OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and a prognostic gene expression signature

Schöpf et al (2019) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and a prognostic gene expression signature. MitoFit Preprint Arch doi:10.26124/mitofit:190003. - »Bioblast link«


MitoFit Do you know what a preprint is? With a preprint you can communicate recent findings to the scientific community, receiving input from other scientists before submitting to a peer-reviewed journal. - »Preprint«


Bioblast alert 2020(06): 2020-02-26

MitoPedia Research is needed on the impact of viral infection on mitochondrial function.

- »Viruses and mitochondrial medicine«


O2k-Network High quality mitochondrial research is increasing rapidly in South Korea.

- »O2k-Network Labs Republic of Korea«


O2k-Publications in the MiPMap An active lifestyle protects cardiac mitochondria

- from the O2k-Network: »KR Busan Han J«, »KR Incheon Kwak HB«

  • No MH, Heo JW, Yoo SZ, Kim CJ, Park DH, Kang JH, Seo DY, Han J, Kwak HB (2020) Effects of aging and exercise training on mitochondrial function and apoptosis in the rat heart. Pflugers Arch 472:179-93. - »Bioblast link«


MitoPedia It is essential to titrate uncouplers in multiple steps for respirometric measurement of electron transfer capacity.
- »Noncoupled respiration«


Bioblast alert 2020(05): 2020-02-20

MitoGlobal Events Registration now open! 21st European Bioenergetics Conference. Marseille, France. 2020 Aug 22-27.

- »EBEC2020«


O2k-Publications in the MiPMap Aging and hyperlipidemia impair aortic mitochondrial function and increase the risk of atherosclerosis

- from the O2k-Network US MI Ann Arbor Beard DA Tyrrell DJ, Blin M, Song J, Wood S, Zhang M, Beard DA, Goldstein D (2019) Age-associated mitochondrial dysfunction accelerates atherogenesis. Circ Res 126:298–314. »Bioblast link«


MitoPedia Spermidine and other calorie restriction mimetics control autophagy and mitochondrial function.

- »Spermidine«


MitoFit Preprint Arch MitoFit Preprint Arch was initiated one year ago on February 19, 2020.

- We invite submissions of mitochondrial preprints.


Bioblast alert 2020(04): 2020-02-07

MitoGlobal Events Save the date! April 24-25, 2020 - The first meeting of the Bioenergetics DE-CH-AT Group aims at exchange and collaboration in bioenergetics between Germany, Switzerland and Austria.

- »Bioenergetics Vienna 2020«


O2k-Publications in the MiPMap Blood cell mitochondrial function does not provide a general substitute for muscle biopsies

- from the O2k-Network: US AR Little Rock Boersheim E Rose S, Carvalho E, Diaz EC, Cotter M, Bennuri SC, Azhar G, Frye RE, Adams SH, Boersheim E (2019) A comparative study of mitochondrial respiration in circulating blood cells and skeletal muscle fibers in women. Am J Physiol Endocrinol Metab 317:E503-E512. - »Bioblast link«


O2k-brief Cronin (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.- »Spermidine«

Nature - Lymphocytes, Cancer - O2k-brief repository


O2k-Publications in the MiPMap Aerobic and resistance training address central defects and peripheral comorbidities in Alzheimer’s disease

- from the O2k-Network: US FL Boca Raton Khamoui AV

Pena GS, Paez HG, Johnson TK, Halle JL, Carzoli JP, Visavadiya NP, Zourdos MC, Whitehurst MA, Khamoui AV (2020) Hippocampal growth factor and myokine cathepsin B expression following aerobic and resistance training in 3xTg-AD mice. Int J Chronic Diseases 2020:Article ID 5919501. - »Bioblast link«


Bioblast alert 2020(03): 2020-01-31

MitoGlobal Events The European Society for Surgical Research Congress early bird registration deadline is Monday February 10, 2020.

- »ESSR 2020 Innsbruck AT«


O2k-Publications in the MiPMap Mitochondrial respiration is oxygen-dependent in human cardiac homogenate preparations

- from the O2k-Network: CZ Prague Krajcova A

Krajčová A, Urban T, Megvinet D, Waldauf P, Balík M, Hlavička J, Budera P, Janoušek L, Pokorná E, Duška F (2020) High resolution respirometry to assess function of mitochondria in native homogenates of human heart muscle. PLOS ONE 15:e0226142. - »Bioblast link«


O2k-Publications in the MiPMap Mitochondrial respiration of blood cells and cardiovascular disease

- from the O2k-Network: FR Strasbourg Zoll J Alfatni A, Riou M, Charles AL, Meyer A, Barnig C, Andres E, Lejay A, Talha S, Geny B (2020) Peripheral blood mononuclear cells and platelets mitochondrial dysfunction, oxidative stress, and circulating mtDNA in cardiovascular diseases. J Clin Med 9 pii:E311. - »Bioblast link«


O2k-Open SupportTake care Reproducibility committment in high-resolution respirometry: quality control in oxygen calibration

In the DatLab 7.4 software, new instrumental DL-Protocols guide the user automatically step-by-step, to calibrate the instrument accurately. Reproducibility is monitored and documented when following user-friendly standard operating procedures (SOP). - »Oxygen calibration - DatLab«


Bioblast alert 2020(02): 2020-01-24

MitoGlobal Events The Association for Psychological Science 2020 conference abstract submission deadline for poster presentations is Friday January 31, 2020.

- » Bioblast link«


O2k-brief Dias et al (2018) Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices. Anal Biochem

- Nervous system »Bioblast link«


O2k-Publications in the MiPMap HRR - high-resolution respirometry and oxygen kinetics 10 years ago: Cell respiration under hypoxia: facts and artefacts in mitochondrial oxygen kinetics. Adv Exp Med Biol 2010.

- »Bioblast link«


News Two websites:

- One new: the Oroboros MarketPlace website  »www.oroboros.at« - One continued: the website of the Oroboros Ecosystem  »www.bioblast.at«


Bioblast alert 2020(01): 2020-01-17

News The Oroboros Ecosystem Agenda 2020 is launched as a signature of the Oroboros Ecosystem.


Gentle Science 2020: a critical year for women, gender equity, and health - a Lancet Editorial


O2k-Publications in the MiPMap Statistical evaluation on replica in HRR with permeabilized skeletal muscle fibers

- from the O2k-Network: AU Melbourne Stepto NK Jacques M, Kuang J, Bishop DJ, Yan X, Alvarez-Romero J, Munson F, Garnham A, Papadimitriou I, Voisin S, Eynon N (2019) Mitochondrial respiration variability and simulations in human skeletal muscle: The Gene SMART study. FASEB J [Epub ahead of print]. - »Bioblast link«


COST Action MitoEAGLE Planning the MitoEAGLE Summit Obergurgl 2020

Members of the Management Committee MitoEAGLE and Working Group Leaders: please submit your suggestions for MitoEAGLE Summit Obergurgl 2020: - Suggested type and title of your personal presentation, according to the MoU and final MitoEAGLE output - Suggested type and title of your personal presentation, according to the MoU and final MitoEAGLE output