NL Amsterdam Wuest RC

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NL Amsterdam Wuest RC

Oroboros O2k-Network

O2k-Network Lab	Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, VU Amsterdam
Address	O/2 gebouw, 13W11, De Boelelaan 1108, 1081 BT Amsterdam,
City	Amsterdam
State/Prov
Country	The Netherlands
Weblink
Contact	Wuest Rob C
Team	Jaspers Richard T
Team previous	Hooijman Pleuni, Stienen G.J.M, Nollet Edgar, Van Hinsbergh Victor, Sequeira Oliveira Vasco
Status	2 Power-O2k 2006-; previous: NL Amsterdam Serlie MJ
Oroboros Events	MiPschool 2018, MitoEAGLE 2018 LV, IOC130, MitoEAGLE 2017 ES, IOC119, MitoEAGLE 2016 IT, IOC80
Topics	Bio-energetics, heart failure, cardiac muscle, skeletal muscle, oxidative stress

O2k-Publications

	Published	Reference
Heinonen 2020 Sci Rep	2020	Heinonen I, Sorop O, van Dalen BM, Wüst RCI, van de Wouw J, de Beer VJ, Octavia Y, van Duin RWB, Hoogstrate Y, Blonden L, Alkio M, Anttila K, Stubbs A, van der Velden J, Merkus D, Duncker DJ (2020) Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement. Sci Rep 10:13173.
Ajime 2020 Nicotine Tob Res	2020	Ajime TT, Serré J, Wüst RCI, Messa GAM, Poffé C, Swaminathan A, Maes K, Janssens W, Troosters T, Degens H, Gayan-Ramirez G (2020) Two weeks smoking cessation reverses cigarette smoke-induced skeletal muscle atrophy and mitochondrial dysfunction in mice. Nicotine Tob Res [Epub ahead of print].
Chabi 2019 MitoFit Preprint Arch EA	2019-10-10	Chabi Béatrice, Ost M, Gama-Perez P, Dahdah N, Lemieux H, Holody CD, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Pesta D, Calabria E, Casado M, Fernandez-Ortiz M, Acuña-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wüst R, Dayanidhi S, Gnaiger E, Doerrier C, Garcia-Roves PM (2019) Generating reference values on mitochondrial respiration in permeabilized muscle fibers. MitoFit Preprint Arch doi:10.26124/mitofit:ea19.MitoEAGLE.0001.
Miranda-Silva 2019 Acta Physiologica	2019	Miranda-Silva D, Wüst RCI, Conceição G, Gonçalves-Rodrigues P, Gonçalves N, Gonçalves A, Kuster DWD, Leite-Moreira AF, van der Velden J, de Sousa Beleza JM, Magalhães J, Stienen GJM, Falcão-Pires I (2019) Disturbed cardiac mitochondrial and cytosolic calcium handling in a metabolic risk-related rat model of heart failure with preserved ejection fraction. Acta Physiol e13378.
Van den Berg 2017 Am J Respir Crit Care Med	2017	van den Berg M, Hooijman PE, Beishuizen A, de Waard MC, Paul MA, Hartemink KJ, van Hees HWH, Lawlor MW, Brocca L, Bottinelli R, Pellegrino MA, Stienen GJM, Heunks LMA, Wüst RCI, Ottenheijm CAC (2017) Diaphragm atrophy and weakness in the absence of mitochondrial dysfunction in the critically ill. Am J Respir Crit Care Med 196:1544-58.
Nauta 2016 Thesis	2016	Nauta TD (2016) HIF-2α regulates in vitro neovascularization during hypoxia. Doctoral Dissertation p206.
Wijermars 2016 Kidney Int	2016	Wijermars LG, Schaapherder AF, de Vries DK, Verschuren L, Wuest RC, Kostidis S, Mayboroda OA, Prins F, Ringers J, Bierau J, Bakker JA, Kooistra T, Lindeman JH (2016) Defective postreperfusion metabolic recovery directly associates with incident delayed graft function. Kidney Int 90:181-91.
Wuest 2016 Cardiovasc Res	2016	Wüst RC, de Vries HJ, Wintjes LT, Rodenburg RJ, Niessen HW, Stienen GJ (2016) Mitochondrial complex I dysfunction and altered NAD(P)H kinetics in rat myocardium in cardiac right ventricular hypertrophy and failure. Cardiovasc Res 111:362-72.
Wijermars 2016 Am J Transplant	2016	Wijermars LG, Schaapherder AF, Kostidis S, Wüst RC, Lindeman JH (2016) Succinate accumulation and ischemia reperfusion injury: of mice but not men - A study in renal ischemia reperfusion. Am J Transplant 16:2741-6.
Wuest 2015 J Physiol	2015	Wüst RC, Helmes M, Stienen GJ (2015) Rapid changes in NADH and flavin autofluorescence in rat cardiac trabeculae reveal large mitochondrial complex II reserve capacity. J Physiol 593:1829-40.
Wuest 2012 Am J Physiol Heart Circ Physiol	2012	Wuest RC, Myers DS, Stones R, Benoist D, Robinson PA, Boyle JP, Peers C, White E, Rossiter HB (2012) Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure. Am J Physiol Heart Circ Physiol 302: H402-H411.

O2k-Abstracts

	Published	Reference
Doerrier 2020 PaduaMuscleDays Poster	2020	Doerrier C, Gama-Perez P, Chabi B, Ost M, Distefano G, Pesta D, Dahdah N, Lemieux H, Holody C, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Calabria E, Casado M, Fernandez-Ortiz M, Acuna-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wuest R, Dayanidhi S, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen PM, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Commitment to reproducibility in mitochondrial respiration studies with permeabilized muscle fibers. PaduaMuscleDays.
Chabi 2019 MiP2019	2019	Generating reference values on mitochondrial respiration in permeabilized muscle fibers.
Wuest 2019 MiPschool Coimbra	2019	Altered mitochondrial metabolism in the diabetic heart.
Nollet 2018 IOC130	2018	Mitochondrial dysfunction in hypertrophic cardiomyopathy.
Wuest 2018 MiP2018b	2018	The antibiotic doxycycline impairs cardiac mitochondrial and contractile function.
De Goede 2018 MiP2018	2018	Timing of feeding behavior affects daily rhythms in body temperature and muscle mitochondrial metabolism.
Wuest 2017 Abstract MITOEAGLE Barcelona	2017	Mitochondrial Complex I function in heart failure: different angles to analyze mitochondrial function.