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Mayan MD

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Mayan MD


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1

COST WG3: WG3 COST WG4: WG4


Name Mayán María D., PhD

CellCOM Group Head

Institution
María D. Mayán

Instituto de Investigación Biomédica de A Coruña (INIBIC)

CH-Universitario de A Coruña (CHUAC - XXIAC) SERGAS

Address C/ As Xubias 84, 15006
City A Coruña
State/Province
Country Spain
Email [email protected]
Weblink http://www.mayan-lab.com
O2k-Network Lab


MitoEAGLE Feedback

We investigate connexins function on the process of diseases. We have recently started a project in order to find and design new molecules to target Cx43 and Cx26. We have access to human samples and animal models to test those molecules. We focus our research on the pathophysiology and treatment options for osteoarthritis, wound healing, melanoma and breast cancer. It has been demonstrated that localization of connexin43 (Cx43) is pivotal for mitochondrial function. It has been reported that mitochondrial Cx43 is required for optimal mitochondrial ATP-production. In fact, mitochondrial Cx43 is essential for the ischemic preconditioning which offers potent protection against repercussion injury. The existence of mitochondrial Cx43 raises a number of new questions. - Maria D. Mayan (2016).


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