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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
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Pamenter 2018 PLoS One | 2018 | Pamenter ME, Lau GY, Richards JG (2018) Effects of cold on murine brain mitochondrial function. PLoS One 13:e0208453. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Mouse | Nervous system |
Pamenter 2021 Biol Lett | 2021 | Pamenter ME, Gomez CR, Richards JG, Milsom WK (2021) Mitochondrial responses to prolonged anoxia in brain of red-eared slider turtles. Biol Lett 12:20150797. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized cells | Reptiles | Nervous system |
Paradis 2019 Antioxidants (Basel) | 2019 | Paradis S, Charles AL, Georg I, Goupilleau F, Meyer A, Kindo M, Laverny G, Metzger D, Geny B (2019) Aging exacerbates ischemia-reperfusion-induced mitochondrial respiration impairment in skeletal muscle. Antioxidants (Basel) 8:E168. | LEAK OXPHOS | N S CIV | Permeabilized tissue | Mouse | Skeletal muscle |
Parajuli 2012 PLoS One | 2012 | Parajuli N, Campbell LH, Marine A, Brockbank KG, Macmillan-Crow LA (2012) MitoQ blunts mitochondrial and renal damage during cold preservation of porcine kidneys. PLoS One 7:e48590. | OXPHOS | N S CIV | Permeabilized tissue | Pig | Kidney |
Parker 2020 Thesis | 2020 | Parker EP (2020) The effect of isoleucine supplementation of peripheral blood mononuclear cell metabolism in subjects with type 2 diabetes. URS Thesis 31. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
Patil 2014 Am J Physiol Renal Physiol | 2014 | Patil NK, Parajuli N, Macmillan-Crow LA, Mayeux PR (2014) Inactivation of renal mitochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria targeted antioxidant mitigates injury. Am J Physiol Renal Physiol 306:F734-43. | LEAK OXPHOS | N S CIV | Permeabilized tissue | Mouse | Kidney |
Patyal 2022 Int J Mol Sci | 2022 | Patyal P, Nguyen B, Zhang X, Azhar G, Ameer FS, Verma A, Crane J, Kc G, Che Y, Wei JY (2022) Rho/SRF inhibitor modulates mitochondrial functions. https://doi.org/10.3390/ijms231911536 | LEAK ROUTINE OXPHOS ET | N S CIV ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle |
Pecina 2003 Biochim Biophys Acta | 2003 | Pecina P, Capkova M, Chowdhury SK, Drahota Z, Dubot A, Vojtiskova A, Hansikova H, Houstekova H, Zeman J, Godinot C, Houstek J (2003) Functional alteration of cytochrome c oxidase by SURF1 mutations in Leigh syndrome. Biochim Biophys Acta 1639:53-63. | LEAK OXPHOS ET | S CIV | Intact cells Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Pecina 2014 Abstract MiP2014 | Manifestation of mitochondrial disorders of nuclear origin in lymphocytes. | OXPHOS | N S Gp CIV | Permeabilized cells | Human | Blood cells Lymphocyte | |
Pecina 2014 Biochim Biophys Acta Clinical | 2014 | Pecina P, Houstkova H, Mracek T, Pecinova A, Nuskova H.Tesarova M, Hansikova H, Janota J, Zemanc J, Houstek J (2014) Noninvasive diagnostics of mitochondrial disorders in isolated lymphocytes with high resolution respirometry. Biochim Biophys Acta Clinical 2:62–71. | LEAK OXPHOS | N Gp CIV Other combinations ROX | Permeabilized cells | Human | Blood cells Lymphocyte |
Pedersen 2022 Nat Commun | 2022 | Pedersen JS, Rygg MO, Chrøis K, Sustarsic EG, Gerhart-Hines Z, Wever Albrechtsen NJ, Serizawa RR, Kristiansen VB, Basse AL, Boilesen AEB, Olsen BH, Hansen T, Gluud LL, Madsbad S, Larsen S, Bendtsen F, Dela F (2022) Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration. https://doi.org/10.1038/s41467-022-30629-5 | LEAK OXPHOS ET | F N S CIV NS | Permeabilized tissue | Human | Liver Fat |
Pelster 2020 PLoS One | 2020 | Pelster B, Wood CM, Campos DF, Val AL (2020) Cellular oxygen consumption, ROS production and ROS defense in two different size-classes of an Amazonian obligate air-breathing fish (Arapaima gigas). PLoS One 15:e0236507. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Fishes | Kidney Lung;gill |
Permer 2017 Bachelor Thesis | 2017 | Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Intact cells | Human | Other cell lines HEK |
Peruzzotti-Jametti 2020 bioRxiv | 2020 | Peruzzotti-Jametti L, Bernstock JD, Manferrari G, Rogall R, Fernandez-Vizarra E, Williamson JC, Braga A, van den Bosch A, Leonardi T, Kittel A, Benincá C, Vicario N, Tan S, Bastos C, Bicci I, Iraci N, Smith JA, Lehner PJ, Buzas EI, Faria N, Zeviani M, Frezza C, Brisson A, Matheson NJ, Viscomi C, Pluchino S (2020) Neural stem cells traffic functional mitochondria via extracellular vesicles to correct mitochondrial dysfunction in target cells. bioRxiv doi: https://doi.org/10.1101/2020.01.29.923441 . | LEAK | N S Gp CIV ROX | Permeabilized cells | Mouse | Stem cells |
Peruzzotti-Jametti 2021 PLoS Biol | 2021 | Peruzzotti-Jametti L, Bernstock JD, Willis CM, Manferrari G, Rogall R, Fernandez-Vizarra E, Williamson JC, Braga A, van den Bosch A, Leonardi T, Krzak G, Kittel A, Beninca C, Vicario N, Tan S, Bastos C, Bicci I, Iraci N, Smith JA, Peacock B, Muller KH, Lehner PJ, Buzas EI, Faria N, Zeviani M, Frezza C, Brisson A, Matheson NJ, Viscomi C, Pluchino S (2021) Neural stem cells traffic functional mitochondria via extracellular vesicles. PLoS Biol 19:3001166. | LEAK OXPHOS | N S Gp CIV ROX | Permeabilized cells | Mouse | Nervous system Stem cells |
Petry 2022 Antioxidants (Basel) | 2022 | Petry SF, Römer A, Rawat D, Brunner L, Lerch N, Zhou M, Grewal R, Sharifpanah F, Sauer H, Eckert GP, Linn T (2022) Loss and recovery of glutaredoxin 5 is inducible by diet in a murine model of diabesity and mediated by free fatty acids in vitro. https://doi.org/10.3390/antiox11040788 | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Mouse | Islet cell;pancreas;thymus |
Peyta 2016 Biochim Biophys Acta | 2016 | Peyta L, Jarnouen K, Pinault M, Guimaraes C, Pais de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S (2016) Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells. Biochim Biophys Acta 1857:443-53. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells | Human | Liver Other cell lines |
Pham 2020 Eur J Appl Physiol | 2020 | Pham T, MacRae CL, Broome SC, D'souza RF, Narang R, Wang HW, Mori TA, Hickey AJR, Mitchell CJ, Merry TL (2020) MitoQ and CoQ10 supplementation mildly suppresses skeletal muscle mitochondrial hydrogen peroxide levels without impacting mitochondrial function in middle-aged men. Eur J Appl Physiol 120:1657-69. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Pharaoh 2019 Mol Neurobiol | 2019 | Pharaoh G, Owen D, Yeganeh A, Premkumar P, Farley J, Bhaskaran S, Ashpole N, Kinter M, Van Remmen H, Logan S (2019) Disparate central and peripheral effects of circulating IGF-1 deficiency on tissue mitochondrial function. Mol Neurobiol 57:1317-31. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue Isolated mitochondria Intact cells | Mouse | Skeletal muscle Nervous system Fat |
Pharaoh 2021 JCSM Rapid Commun | 2021 | Pharaoh G, Brown J, Ranjit R, Ungvari Z, Van Remmen H (2021) Reduced adenosine diphosphate sensitivity in skeletal muscle mitochondria increases reactive oxygen species production in mouse models of aging and oxidative stress but not denervation. https://doi.org/10.1002/rco2.29 | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Picard 2012 PLoS One | 2012 | Picard M, Wright KJ, Ritchie D, Thomas MM, Hepple RT (2012) Mitochondrial function in permeabilized cardiomyocytes is largely preserved in the senescent rat myocardium. PLoS One 7:e43003. | LEAK OXPHOS | N CIV NS | Permeabilized tissue | Rat | Heart |
Pichaud 2013 Abstract MiP2013 | Pichaud N, Blier PU(2013) Importance of mitochondrial haplotypes in the expression of metabolic phenotypes under different conditions. Mitochondr Physiol Network 18.08. | LEAK OXPHOS ET | N S Gp CIV NS ROX | Permeabilized tissue | Drosophila Hexapods | Skeletal muscle | |
Pichaud 2019 Front Genet | 2019 | Pichaud N, Bérubé R, Côté G, Belzile C, Dufresne F, Morrow G, Tanguay RM, Rand DM, Blier PU (2019) Age dependent dysfunction of mitochondrial and ROS metabolism induced by mitonuclear mismatch. Front Genet 10:130. | LEAK OXPHOS ET | N Gp CIV ROX | Permeabilized tissue | Drosophila | Skeletal muscle |
Piel 2014 Acta Physiol (Oxf) | 2014 | Piel S, Ehinger JK, Elmér E, Hansson Magnus J (2014) Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial Complex I inhibition. Acta Physiol (Oxf) 213:171-80. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Blood cells Other cell lines Platelet |
Ping 2015 Oxid Med Cell Longev | 2015 | Ping Z, Zhang LF, Cui YJ, Chang YM, Jiang CW, Meng ZZ, Xu P, Liu HY, Wang DY, Cao XB (2015) The protective effects of Salidroside from exhaustive exercise-induced heart injury by enhancing the PGC-1𝛼–NRF1/NRF2 pathway and mitochondrial respiratory function in rats. Oxid Med Cell Longev Article ID 876825. | OXPHOS ET | N S CIV ROX | Permeabilized tissue | Rat | Heart |
Plecita-Hlavata 2015 Am J Respir Cell Mol Biol | 2015 | Plecitá-Hlavatá L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'alessandro A, El Kasmi KC, Ježek P, Stenmark KR (2015) Constitutive reprogramming of fibroblast mitochondrial metabolism in pulmonary hypertension. Am J Respir Cell Mol Biol 55:47-57. | LEAK ROUTINE OXPHOS ET | N CIV Other combinations | Isolated mitochondria Intact cells | Human Bovines | Endothelial;epithelial;mesothelial cell Fibroblast |
Pohland 2016 Neurochem Res | 2016 | Pohland M, Hagl S, Pellowska M, Wurglics M, Schubert-Zsilavecz M, Eckert GP (2016) MH84: a novel γ-secretase modulator/PPARγ agonist-improves mitochondrial dysfunction in a cellular model of Alzheimer's disease. Neurochem Res 41:231-42. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Kidney HEK |
Porplycia 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | Porplycia D, Lau GY, McDonald J, Chen Z, Richards JG, Moyes CD (2017) Subfunctionalization of COX4 paralogs in fish. Am J Physiol Regul Integr Comp Physiol 312:R671-R680. | LEAK | CIV ROX | Isolated mitochondria | Fishes | Skeletal muscle |
Power 2016 Am J Physiol Heart Circ Physiol | 2016 | Power AS, Pham T, Loiselle DS, Crossman DH, Ward ML, Hickey AJ (2016) Impaired ADP channeling to mitochondria and elevated reactive oxygen species in hypertensive hearts. https://doi.org/10.1152/ajpheart.00050.2016 | LEAK OXPHOS ET | N CIV NS | Permeabilized tissue Homogenate | Rat | Heart |
Powers 2019 Neurourol Urodyn | 2019 | Powers SA, Ryan TE, Pak ES, Fraser MO, McClung JM, Hannan JL (2019) Chronic high-fat diet decreased detrusor mitochondrial respiration and increased nerve-mediated contractions. Neurourol Urodyn 38:1524-32. | LEAK OXPHOS | N S CIV NS | Homogenate | Mouse | Other cell lines |
Price 2016 J Thermal Biol | 2016 | Price ER, Sirsat TS, Sirsat SKG, Kang G, Keereetaweep J, Aziz M, Chapman KD, Dzialowski EM (2016) Thermal acclimation in American alligators: Effects of temperature regime on growth rate, mitochondrial function, and membrane composition. J Thermal Biol p11. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Reptiles | Heart Skeletal muscle |
Prouteau-Angebault 2013 Abstract IOC75 | Prouteau-Angebault C (2013) Are cardiolipins involved in the mitochondrial respiratory chain defect in OPA1 mouse model? Mitochondr Physiol Network 18.03. | OXPHOS | N S CIV | Permeabilized cells Homogenate Isolated mitochondria | Mouse | Skeletal muscle Nervous system | |
Pruett 2022 Biol Sex Differ | 2022 | Pruett JE, Everman SJ, Hoang NH, Salau F, Taylor LC, Edwards KS, Hosler JP, Huffman AM, Romero DG, Yanes Cardozo LL (2022) Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition. https://doi.org/10.1186/s13293-022-00455-x | CIV | Homogenate | Rat | Fat | |
Qi 2017 Ann Allergy Asthma Immunol | 2017 | Qi S, Cindy Barnig C, Charles AL, Poirot A, Meyer A, Clere-Jehl R, de Blay F, Geny B (2017) Nasal allergen challenge in allergic rhinitis induces mitochondrial dysfunction of peripheral blood mononuclear cells. Ann Allergy Asthma Immunol 118:367-9. | OXPHOS LEAK | N S CIV | Permeabilized cells | Human | Blood cells Lymphocyte |
Qu 2018 FASEB J | 2018 | Qu C, Zhang S, Wang W, Li M, Wang Y, van der Heijde-Mulder M, Shokrollahi E, Hakim MS, Raat NJH, Peppelenbosch MP, Pan Q (2018) Mitochondrial electron transport chain complex III sustains hepatitis E virus replication and represents an antiviral target. FASEB J 33:1008-19. | LEAK ROUTINE | CIV ROX | Intact cells | Human | Liver |
Quemeneur 2022 Sci Rep | 2022 | Quéméneur JB, Danion M, Cabon J, Collet S, Zambonino-Infante JL, Salin K (2022) The relationships between growth rate and mitochondrial metabolism varies over time. https://doi.org/10.1038/s41598-022-20428-9 | LEAK OXPHOS | N CIV NS ROX | Homogenate | Fishes | Skeletal muscle |
Rackham 2016 Cell Rep | 2016 | Rackham O, Busch JD, Matic S, Siira SJ, Kuznetsova I, Atanassov I, Ermer JA, Shearwood AM, Richman TR, Stewart JB, Mourier A, Milenkovic D, Larsson NG, Filipovska A (2016) Hierarchical RNA processing is required for mitochondrial ribosome assembly. Cell Rep 16:1874-90. | LEAK OXPHOS ET | N S CIV NS Other combinations | Isolated mitochondria | Mouse | Heart |
Radenkovic 2017 Biochem Pharmacol | 2017 | Radenkovic F, Holland OJ, Vanderlelie JJ, Perkins AV (2017) Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation. Biochem Pharmacol 146:42-52. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Other cell lines |
Rajasekaran 2018 FASEB J | 2018 | Rajasekaran R, Felser A, Nuoffer JM, Dufour JF, St-Pierre MV (2018) The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metabolism. FASEB J 32:5143-61. | LEAK OXPHOS ET | N S CIV ROX | Isolated mitochondria | Mouse | Liver |
Rajendran 2019 EMBO Mol Med | 2019 | Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Auvinen P, Mervaala E, Jacobs HT, Szibor M, Fellman V, Kallijärvi J (2019) Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy. EMBO Mol Med 11:e9456. | LEAK OXPHOS ET | N S CIV NS | Isolated mitochondria | Mouse | Liver Kidney Heart |
Rajkumar 2018 Metabolism | 2018 | Rajkumar A, Liaghati A, Chan J, Lamothe G, Dent R, Doucet É, Rabasa-Lhoret R, Prud'homme D, Harper ME, Tesson F (2018) ACSL5 genotype influence on fatty acid metabolism: a cellular, tissue, and whole-body study. Metabolism 83:271-9. | OXPHOS ET | F N CIV NS | Permeabilized cells | Human Mouse | Skeletal muscle Other cell lines |
Rampello 2018 Microb Cell | 2018 | Rampello NG, Stenger M, Westermann B, Osiewacz HD (2018) Impact of F1Fo-ATP-synthase dimer assembly factors on mitochondrial function and organismic aging. Microb Cell 5:198–207. | OXPHOS | N CIV | Isolated mitochondria | Fungi | |
Rasmussen 1996 Biochem J | 1996 | Rasmussen UF, Rasmussen HN, Andersen AJ, Fogd Jørgensen P, Quistorff B. (1996) Characterization of mitochondria from pig muscle: higher activity of exo-NADH oxidase in animals suffering from malignant hyperthermia. Biochem J 315:659-63. | LEAK OXPHOS | N S CIV NS | Isolated mitochondria | Pig | Skeletal muscle |
Rawat 2019 J Mol Biol | 2019 | Rawat S, Anusha V, Jha M, Sreedurgalakshmi K, Raychaudhuri S (2019) Aggregation of respiratory complex subunits marks the onset of proteotoxicity in proteasome inhibited cells. J Mol Biol 431:996-1015. | OXPHOS LEAK | N S CIV ROX | Permeabilized cells | Mouse | Nervous system Other cell lines |
Reda 2019 Sci Rep | 2019 | Reda A, Refaat A, Abd-Rabou AA, Mahmoud AM, Adel M, Sabet S, Ali SS (2019) Role of mitochondria in rescuing glycolytically inhibited subpopulation of triple negative but not hormone-responsive breast cancer cells. Sci Rep 9:13748. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
Regueira 2009 Liver Int | 2009 | Regueira T, Lepper PM, Brandt S, Ochs M, Vuda M, Takala J, Jakob SM, Djafarzadeh S (2009) Hypoxia inducible factor-1alpha induction by tumour necrosis factor-alpha, but not by toll-like receptor agonists, modulates cellular respiration in cultured human hepatocytes. Liver Int 10:1582-92. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Liver |
Reich 2016 Thesis | 2016 | Reich V (2016) Pathophysiologie und Verfahrensentwicklung: Mechanismen der Metabolisierung von Schwefelwasserstoff im mitochondrialen Atmungskreislauf von Lungenalveolarmakrophagen. Dissertation p91. | LEAK OXPHOS ET | N S CIV NS ROX | Intact cells Permeabilized cells | Mouse | Macrophage-derived |
Repp 2019 Thesis | 2019 | Repp BM (2019) Identification and verification of novel disease-causing genes and therapy options for patients with mitochondrial disorders – Focus on ACAD9. PhD Thesis 178. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | HEK |
Reutzel 2018 Oxid Med Cell Longev | 2018 | Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Reutzel 2020 Oxid Med Cell Longev | 2020 | Reutzel M, Grewal R, Dilberger B, Silaidos C, Joppe A, Eckert GP (2020) Cerebral mitochondrial function and cognitive performance during aging: A longitudinal study in NMRI mice. Oxid Med Cell Longev 2020:4060769. | LEAK ET OXPHOS | N S CIV ROX | Isolated mitochondria | Mouse | Nervous system |